4 completed, 1 terminated, 1 unknown. 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Randomised Study of Azacitidine Versus Azacitidine With Vorinostat in Patients With AML or High Risk MDS Azacitidine, Vorinostat - Leukemia, Myeloid, Acute | Phase 2 | Completed | University of Birmingham | 260 | 2012-09-01 | 2021-05-05 |
| WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation p.DOM-WT1-37 DNA Vaccine and p.DOM-WT1-126 DNA Vaccine - Leukaemia (Acute), Leukaemia (Chronic) | Phase 2 | Completed | University Hospital Southampton NHS Foundation Trust | 23 | 2011-02-01 | 2018-09-07 |
| RESPeCT: Revlimid Early Stage Poor Prognosis Chronic Lymphocytic Leukaemia (CLL) Trial Lenalidomide - Chronic Lymphocytic Leukaemia | Phase 2 | Terminated | The Christie NHS Foundation Trust | 1 | 2010-05-01 | 2011-12-05 |
| Lentivirus Transduced Acute Myeloid Leukaemia Blasts Expressing B7.1 (CD80) and IL-2 RFUSIN2-AML1, Donor leukocyte infusion (DLI), RFUSIN2-AML1 and donor leukocyte infusion - Leukemia, Myeloid, Acute | Phase 1 | Unknown | King's College Hospital NHS Trust | 24 | 2008-05-01 | 2008-07-18 |
| Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia chlorambucil, cyclophosphamide, doxorubicin hydrochloride - Leukemia | Phase 3 | Completed | Leukemia Research Fund | 1999-10-01 | 2013-12-18 | |
| Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome cytarabine, daunorubicin hydrochloride, etoposide - Leukemia, Myelodysplastic Syndromes | Phase 3 | Completed | Leukemia Research Fund | 2000 | 1998-12-01 | 2013-12-18 |
Leukemia, Myeloid, Acute (4) · Leukemia (3) · Anemia, Refractory, with Excess of Blasts (1) · Bronchiolitis Obliterans Syndrome (1) · Congenital Abnormalities (1) · Leukemia, B-Cell (1) · Leukemia, Erythroblastic, Acute (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Megakaryoblastic, Acute (1) · Leukemia, Monocytic, Acute (1) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (1) · Leukemia, Myelomonocytic, Acute (1) · Leukemia, Myelomonocytic, Chronic (1) · Myelodysplastic Syndromes (1) · Myelodysplastic-Myeloproliferative Diseases (1)
Azacitidine (1) · Chlorambucil (1) · Cyclophosphamide (1) · Cytarabine (1) · Daunorubicin (1) · Doxorubicin (1) · Etoposide (1) · Hydroxyurea (1) · Idarubicin (1) · Lenalidomide (1) · Mitoxantrone (1) · Prednisolone (1) · Thioguanine (1) · Tretinoin (1) · Vincristine (1)
United Kingdom (6) · Argentina (1) · Croatia (1) · Greece (1) · Ireland (1) · Italy (1) · New Zealand (1) · Russia (1)
Adrian Bloor (1) · Alan K. Burnett, MD, FRCP (1) · Charles F Craddock, Professor (1) · Daniel Catovsky, MD (1) · Ghulam J Mufti (1)
PMID 17315155, PMID 17658394, PMID 18219306, PMID 18502835, PMID 19016733, PMID 19291085, PMID 20511662, PMID 21483000, PMID 21659360, PMID 22168274, PMID 23091097
2009 (2)