1 active not recruiting, 1 completed, 1 recruiting, 1 unknown. 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard Treatment physician-selected treatment, Regorafenib + Envafolimab - GIST - Gastrointestinal Stromal Tumor, KIT Gene Mutation | Phase 2 | Recruiting | Jian Li | 100 | 2025-07-14 | 2026-04-30 |
| JAB-21822 Combined With Chemotherapy and Bevacizumab in Second-line KRAS G12C CRC JAB-21822, standard second-line chemotherapy, Bevacizumab - Colorectal Cancer | Phase 1 | Active not recruiting | Jian Li | 30 | 2025-03-20 | 2026-01-08 |
| Screening for Monoclonal Gammopathy in Individuals Undergoing Physical Examinations Using iMS-LC Assay Technology. M protein detection by iMS-LC Assay - M Protein, Monoclonal Gammopathy | Unknown | Jian Li | 15600 | 2024-07-01 | 2024-07-09 | |
| BCD With or Without Doxycycline in Mayo Stage II-III Light Chain Amyloidosis Patients Doxycycline, Bortezomib, Cyclophosphamide - Amyloidosis; Systemic | Not applicable | Completed | Jian Li | 140 | 2018-04-21 | 2021-02-23 |
Colorectal Neoplasms (1) · Gastrointestinal Stromal Tumors (1) · Immunoglobulin Light-chain Amyloidosis (1) · Monoclonal Gammopathy of Undetermined Significance (1) · Paraproteinemias (1) · Piebaldism (1)
Bevacizumab (1) · Bortezomib (1) · Cyclophosphamide (1) · Dexamethasone (1) · Doxycycline (1) · Folfox protocol (1) · envafolimab (1) · regorafenib (1)
China (4)
PMID 15365071, PMID 22331188, PMID 25027514, PMID 25580702, PMID 26117060, PMID 28279033, PMID 34503349