4 completed, 2 terminated. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 2 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Terameprocol in Treating Patients With Recurrent High Grade Glioma Terameprocol, Pharmacological Study - High Grade Glioma (III or IV) | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 20 | 2018-05-03 | 2023-10-06 |
| Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia Terameprocol (EM-1421) - Leukemias, Acute Myeloid Leukemia (AML) | Phase 1 | Terminated | Erimos Pharmaceuticals | 16 | 2007-08-01 | 2016-02-23 |
| A Phase 1 Continuous Intravenous Infusion Study of Terameprocol (EM-1421) in Subjects With Refractory Solid Tumors Terameprocol (EM-1421) - Refractory Solid Tumors, Lymphoma | Phase 1 | Terminated | Erimos Pharmaceuticals | 21 | 2007-05-01 | 2016-02-23 |
| Dose Escalation Study of EM-1421 for the Treatment of Recurrent or Refractory Solid Tumors EM-1421 - Cancer | Phase 1 | Completed | Erimos Pharmaceuticals | 30 | 2005-12-01 | 2008-01-24 |
| A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia EM-1421 - Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Completed | Erimos Pharmaceuticals | 8 | 2004-11-01 | 2016-02-23 |
| Study of Intralesional Injection of M4N in Patients With Refractory Malignant Tumors of the Head and Neck M4N - Head and Neck Neoplasms | Phase 1 | Completed | Erimos Pharmaceuticals | 9 | 2003-01-01 | 2016-02-23 |
Glioma (1) · Head and Neck Neoplasms (1) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Leukemia, Myelomonocytic, Chronic (1) · Lymphoma (1) · Myelodysplastic Syndromes (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Uterine Cervical Dysplasia (1)
terameprocol (6)
United States (6)
Neil Frazer, MB, ChB (2) · Manmeet Ahluwalia, MD (1) · Neil Frazer, MB (1)
UM1CA137443 (1)