2 active not recruiting, 1 not yet recruiting, 1 no longer available, 1 recruiting. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 2, Recruiting 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma APG-157, Surgery, Radiation/Chemotherapy - Head and Neck Cancer, Head and Neck (HNSCC) | Phase 3 | Not yet recruiting | Aveta Biomics, Inc. | 826 | 2026-07-01 | 2026-07-01 |
| Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab APG-157 - Glioma, Glioblastoma Multiforme | Phase 1 / Phase 2 | Active not recruiting | Aveta Biomics, Inc. | 30 | 2023-12-13 | 2026-10-05 |
| A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia APG-157 - Oropharyngeal Dysplasia, Oral Cavity Dysplasia | Phase 2 | Recruiting | Elizabeth J Franzmann | 32 | 2023-05-24 | 2026-01-14 |
| Safety and Efficacy of APG-157 in Head and Neck Cancer APG-157 - Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity | Phase 2 | Active not recruiting | Aveta Biomics, Inc. | 24 | 2022-04-22 | 2026-01-16 |
| Treatment of Recurrent GBM With APG-157 Via Expanded Access APG-157 - Glioblastoma, Glioblastoma Multiforme | No longer available | Aveta Biomics, Inc. | 2024-08-09 |
Glioblastoma (2) · Head and Neck Neoplasms (2) · Mouth Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Disease Progression (1) · Glioma (1) · Oropharyngeal Neoplasms (1)
Drug Therapy (1) · Radiation (1) · Surgical Procedures, Operative (1)
United States (3)
Elizabeth Franzmann, MD (1) · Elizabeth J Franzmann, MD (1) · Joon Uhm, MD (1) · Marilene B Wang, MD (1) · Nicole Shonka, MD (1)