7 completed, 2 withdrawn, 1 active not recruiting, 1 terminated. 4 Phase 2, 3 Phase 1, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Zestril: new trials by email Literature Review of Zestril trials Research Report on Zestril
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OptiZ: Real World Evidence Study Zestril - Hypertension | Withdrawn | Closed Loop Medicine | 2025-03-01 | 2026-03-20 | ||
| Personalised Dose Optimisation of Zestril Supported by the Digital Blood Pressure Diary in a Primary Care Environment in England: Pragmatic Observational Pilot Study for Remote Hypertension Treatment Zestril - Uncomplicated Hypertension | Completed | Closed Loop Medicine | 20 | 2024-04-15 | 2026-03-20 | |
| A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026) Warfarin, Enlicitide Decanoate, Lisinopril - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 36 | 2024-04-01 | 2025-01-15 |
| Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study Biospecimen Collection, Lisinopril, Liver Ultrasonographic Elastography - Hepatocellular Carcinoma, Nonalcoholic Steatohepatitis | Phase 2 | Active not recruiting | Northwestern University | 35 | 2021-05-11 | 2026-08-14 |
| Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial Carvedilol, Lisinopril, Pravastatin - Breast Carcinoma, Hematopoietic and Lymphoid Cell Neoplasm | Phase 2 | Withdrawn | Mayo Clinic | 2020-09-01 | 2023-05-24 | |
| Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery ACEI continuation, ACEI omission - Hypotension on Induction | Phase 4 | Completed | University of Nebraska | 291 | 2015-06-01 | 2023-09-25 |
| Modulation of Heme Oxygenase 1 by Nizatidine and Lisinopril in Healthy Subjects Nizatidine, Lisinopril, Placebo - Gastroparesis | Phase 1 | Completed | Adil Bharucha | 24 | 2014-07-01 | 2015-04-30 |
| Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer lisinopril, placebo - Dyspnea, Non-small Cell Lung Cancer | Phase 2 | Completed | Mayo Clinic | 23 | 2013-05-31 | 2020-01-02 |
| Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors lisinopril, losartan potassium, laboratory biomarker analysis - Hypertension, Unspecified Adult Solid Tumor, Protocol Specific | Phase 2 | Terminated | Wake Forest University Health Sciences | 6 | 2011-02-01 | 2018-08-28 |
| Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril Lisinopril, Hydrochlorothiazide - Hypertension, Grade 1, Hypertension Treatment | Not applicable | Completed | Scripps Translational Science Institute | 2 | 2010-11-01 | 2015-05-20 |
| Comparative Bioavailability Study of Lisinopril Tablets, 10 mg Lisinopril, Zestril - Healthy | Phase 1 | Completed | Par Pharmaceutical, Inc. | 36 | 1999-06-01 | 2011-06-17 |
Hypertension (3) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Dyspnea (1) · Fasting (1) · Gastroparesis (1) · Hematologic Neoplasms (1) · Lymphoma (1) · Lymphoma, Follicular (1) · Non-alcoholic Fatty Liver Disease (1) · Sarcoma (1) · Small Cell Lung Carcinoma (1)
Closed Loop Medicine (2) · Mayo Clinic (2) · Adil Bharucha (1) · Merck Sharp & Dohme LLC (1) · Northwestern University (1) · Par Pharmaceutical, Inc. (1) · Scripps Translational Science Institute (1) · University of Nebraska (1) · Wake Forest University Health Sciences (1)
United States (8) · United Kingdom (2)
Adil Bharucha, MBBS, MD (1) · Bradley Patay, MD (1) · Clifford L Ferguson, MD (1) · Jason F Shiffermiller, MD, MPH (1) · Joerg Herrmann (1) · Ju Dong Yang (1) · Robert Miller, M.D. (1) · Serge Engamba, MD (1) · William Petty (1)
P01DK068055 (1), P30CA015083 (1), P30CA060553 (1), UG1CA242643 (1), UL1RR024150 (1)