4 completed, 3 recruiting, 2 terminated. 4 Phase 1, 3 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 2, Completed 1, Terminated 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 2 | Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Zavegepant: new trials by email Literature Review of Zavegepant trials Research Report on Zavegepant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department Rimegepant, Zavegepant - Migraine, Migraine Disease | Phase 1 | Recruiting | University of South Florida | 100 | 2026-09-15 | 2026-10-27 |
| Acute Migraine Treatment in the ED With Gepants Rimegepant, Zavegepant - Migraine Headaches | Phase 4 | Terminated | Icahn School of Medicine at Mount Sinai | 9 | 2025-06-05 | 2026-04-29 |
| A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine Zavegepant - Acute Treatment of Migraine | Phase 1 | Recruiting | Pfizer | 16 | 2025-05-16 | 2026-09-28 |
| Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications Zavegepant - Migraine | Phase 4 | Recruiting | Mayo Clinic | 200 | 2024-03-22 | 2026-09-17 |
| A Study to Learn About Zavegepant as the Acute Treatment of Migraine in Asian Adults Zavegepant, Placebo - Migraine | Phase 3 | Completed | Pfizer | 1414 | 2023-11-29 | 2026-05-22 |
| A Study to Learn About the Study Medicine Called Zavegepant in Healthy Chinese Adult Participants Zavegepant - Healthy | Phase 1 | Completed | Pfizer | 13 | 2023-10-23 | 2025-01-06 |
| Safety and Efficacy Active Drug vs. Placebo in Subjects With Asthma Zavegepant, Placebo - Asthma | Phase 1 | Terminated | Pfizer | 45 | 2021-10-18 | 2024-07-19 |
| Randomized Trial in Adult Participants With Acute Migraines Zavegepant, Placebo - Migraine | Phase 3 | Completed | Pfizer | 1978 | 2020-10-27 | 2023-04-24 |
| Acute Treatment Trial in Adult Subjects With Migraines Zavegepant, Zavegepant matching placebo, Intranasal Aptar Pharma Unit Dose System - Migraine | Phase 2 / Phase 3 | Completed | Pfizer | 2154 | 2019-03-25 | 2023-09-25 |
Migraine Disorders (7) · Hyperacusis (2) · Nausea (2) · Photophobia (2) · Asthma (1) · Emergencies (1) · Hypersensitivity (1) · Migraine with Aura (1) · Migraine without Aura (1)
Pfizer (6) · Icahn School of Medicine at Mount Sinai (1) · Mayo Clinic (1) · University of South Florida (1)
United States (6) · China (2) · Canada (1) · South Korea (1) · Taiwan (1)
Jonathan Schimmel (1) · Todd Schwedt, MD (1)