4 completed, 3 active not recruiting, 1 unknown. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 4, Active not recruiting 3, Unknown 1 |
Follow XIAFLEX: new trials by email Literature Review of XIAFLEX trials Research Report on XIAFLEX
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease Collagenase Clostridium Histolyticum, RestoreX, Sildenafil - Peyronie Disease | Phase 4 | Active not recruiting | Charitable Union for the Research and Education of Peyronie's Disease | 40 | 2024-10-11 | 2026-08-26 |
| Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease Collagenase Clostridium Histolyticum (CCH) - Peyronie Disease, Sexual Dysfunctions, Psychological | Phase 4 | Active not recruiting | University of Miami | 12 | 2023-10-02 | 2026-06-04 |
| Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery - Peyronie's Disease | Phase 4 | Active not recruiting | Charitable Union for the Research and Education of Peyronie's Disease | 40 | 2020-12-30 | 2026-08-26 |
| Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's Disease Percutaneous Needle Aponeurotomy, XIAFLEX - Dupuytren Contracture, Dupuytren's Disease of Finger | Phase 4 | Unknown | University of Calgary | 334 | 2016-01-01 | 2016-12-21 |
| Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF Xiapex, Needle aponeurotomy - Dupuytren Contracture | Phase 4 | Completed | University Hospital, Akershus | 80 | 2013-10-01 | 2022-04-26 |
| Retreatment of Recurrent Dupuytren's Contractures Collagenase clostridium histolyticum - Dupuytren's Disease | Phase 4 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 52 | 2012-03-01 | 2017-10-05 |
| MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex XIAFLEX - Dupuytren's Disease | Phase 4 | Completed | Hospital for Special Surgery, New York | 5 | 2011-03-01 | 2017-04-17 |
| Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb Injectable clostridial collagenase - Dupuytren's Contracture | Phase 4 | Completed | Indiana Hand to Shoulder Center | 7 | 2010-12-01 | 2015-04-30 |
Dupuytren Contracture (5) · Penile Induration (3) · Contracture (1) · Genital Diseases, Male (1) · Sexual Dysfunctions, Psychological (1) · Surgical Wound (1)
Charitable Union for the Research and Education of Peyronie's Disease (2) · Endo USA Inc., a Keenova Therapeutics Company (1) · Hospital for Special Surgery, New York (1) · Indiana Hand to Shoulder Center (1) · University Hospital, Akershus (1) · University of Calgary (1) · University of Miami (1)
United States (6) · Australia (1) · Canada (1) · Norway (1) · Sweden (1) · United Kingdom (1)
Justin Yeung, MD (1) · Landon Trost, MD (1) · Per-Henrik Randsborg, PhD (1) · Scott W Wolfe, MD (1) · Thomas Masterson, MD (1) · Veronica Urdaneta, MD, MPPH (1)