5 terminated, 4 completed, 2 unknown, 1 recruiting. 5 Phase 2, 4 Not applicable, 2 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 3, Completed 1, Recruiting 1 |
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Vit C: new trials by email Literature Review of Vit C trials Research Report on Vit C
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery Vit C, Standard Preparation - Vasoplegia Syndrome | Not applicable | Completed | Southeast University, China | 40 | 2024-07-01 | 2026-09-16 |
| Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype Vit C, injectable PRF - Thin Gingival Biotype | Phase 4 | Unknown | Cairo University | 13 | 2023-07-01 | 2023-05-03 |
| Effectiveness of Vitamin C Supplementation in Treatment of Rickets Vit C - Nutritional Rickets, Bone Turnover Rate Disorder | Phase 2 / Phase 3 | Completed | Cairo University | 88 | 2022-03-01 | 2023-03-08 |
| Efficacy of Vitamin C on AKI Outcomes in Critically Ill Cirrhotics With Multidrug-resistant Bacterial Infections. Vit C, Standard medical Treatment - Liver Cirrhosis | Not applicable | Completed | Institute of Liver and Biliary Sciences, India | 100 | 2021-09-15 | 2023-11-03 |
| Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia Ascorbic Acid, Carboplatin, Cisplatin - Clonal Cytopenia of Undetermined Significance, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Phase 2 | Recruiting | Mayo Clinic | 80 | 2018-03-23 | 2026-09-28 |
| Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery Ascorbic Acid, Pazopanib Hydrochloride - Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma | Phase 2 | Terminated | Academic and Community Cancer Research United | 5 | 2018-02-16 | 2022-03-31 |
| Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer Ascorbic Acid, Docetaxel, Laboratory Biomarker Analysis - Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma | Phase 2 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 50 | 2016-06-20 | 2023-06-07 |
| Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma Ascorbic Acid, Bevacizumab, Laboratory Biomarker Analysis - Glioblastoma, Glioma | Phase 1 | Terminated | University of Nebraska | 9 | 2016-03-01 | 2023-10-24 |
| High Dose Vitamin C in the Critically Ill Patient Ascorbic Acid, Ringers Lactate or Normal Saline - Shock | Phase 2 | Terminated | Rutgers, The State University of New Jersey | 11 | 2013-02-01 | 2017-05-11 |
| Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis Arsenic Trioxide, Ascorbic Acid, Laboratory Biomarker Analysis - Essential Thrombocythemia, Polycythemia Vera | Phase 1 | Terminated | Roswell Park Cancer Institute | 5 | 2010-04-01 | 2022-07-22 |
| Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins 5% dextrose, Vitamin C, Simvastatin - Hyperglycemia | Not applicable | Completed | US Department of Veterans Affairs | 59 | 2010-03-01 | 2015-03-17 |
| The Effects of Post-Conditioning and Administration of Vitamin C on Intramuscular High Energy Phosphate Levels Vit C, Postconditioning, no intervention - Ischemia Reperfusion Injury | Not applicable | Unknown | Medical University of Vienna | 2007-08-01 | 2007-09-26 |
Carcinoma, Renal Cell (1) · Clear-cell metastatic renal cell carcinoma (1) · Glioblastoma (1) · Glioma (1) · Hodgkin Disease (1) · Hyperglycemia (1) · Hypovolemia (1) · Leukemia, Myelomonocytic, Chronic (1) · Liver Cirrhosis (1) · Lymphoma (1) · Lymphoma, Large B-Cell, Diffuse (1) · Polycythemia Vera (1) · Primary Myelofibrosis (1) · Prostatic Neoplasms (1) · Reperfusion Injury (1)
Cairo University (2) · Academic and Community Cancer Research United (1) · Institute of Liver and Biliary Sciences, India (1) · Mayo Clinic (1) · Medical University of Vienna (1) · Roswell Park Cancer Institute (1) · Rutgers, The State University of New Jersey (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Southeast University, China (1) · US Department of Veterans Affairs (1) · University of Nebraska (1)
United States (7) · Egypt (2) · Austria (1) · China (1) · India (1)
Channing Paller, MD (1) · Eunice Wang, MD (1) · Fatina Fadel, Prof (1) · Jingyuan Xu, M.D. (1) · Lance C Pagliaro (1) · Michael Wolzt, MD, Prof. (1) · Nicole A Shonka, MD (1) · Riham M. Omar, Professor (1) · Thomas E Witzig, M.D. (1) · Thomas J Ebert, MD PhD (1) · Vicente Gracias, MD (1)
P30CA006973 (1), P30CA015083 (1), P30CA036727 (1), P50CA097274 (1)