297 completed, 60 unknown, 40 active not recruiting, 24 terminated. 218 Phase 2, 168 Phase 3, 68 Phase 1, 20 Not applicable, 4 Early Phase 1.
Follow Vincristine Sulfate: new trials by email Literature Review of Vincristine Sulfate trials Research Report on Vincristine Sulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large B-Cell Lymphoma (The "Glofit-RCHOP Study") Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - AIDS-Related Diffuse Large B-cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 1 | Not yet recruiting | National Cancer Institute (NCI) | 15 | 2026-10-09 | 2026-08-13 |
| A Study of BL-M08D1 in Combination With Immunochemotherapy in Patients With Diffuse Large B-Cell Lymphoma BL-M08D1, Rituximab, Gemcitabine Hydrochloride - Diffuse Large B-Cell Lymphoma | Phase 1 / Phase 2 | Not yet recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 204 | 2026-09-01 | 2026-09-14 |
| Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | Children's Oncology Group | 1708 | 2026-08-28 | 2026-07-30 |
| A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Rhabdomyosarcoma | Phase 3 | Recruiting | Children's Oncology Group | 342 | 2026-07-14 | 2026-08-25 |
| Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration - CIC-Rearranged Sarcoma, Metastatic Ewing Sarcoma | Phase 2 / Phase 3 | Terminated | Children's Oncology Group | 2 | 2025-11-10 | 2026-10-05 |
| Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic Lymphoma | Phase 2 | Recruiting | City of Hope Medical Center | 53 | 2025-10-10 | 2026-10-13 |
| Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma Dexamethasone, Vincristine, Inotuzumab - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 128 | 2025-01-23 | 2026-07-16 |
| Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) Dexamethasone, Vincristine, Daunorubicin - T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma | Phase 2 | Recruiting | St. Jude Children's Research Hospital | 100 | 2024-12-27 | 2026-08-10 |
| Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma Dexamethasone, Vincristine, Daunorubicin - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 4 | Recruiting | St. Jude Children's Research Hospital | 850 | 2024-12-26 | 2026-07-14 |
| A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia Biospecimen Collection, Bone Marrow Aspiration, Calaspargase Pegol - Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | Children's Oncology Group | 78 | 2024-01-08 | 2026-08-25 |
| A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin - Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 | Phase 3 | Recruiting | National Cancer Institute (NCI) | 1875 | 2023-05-11 | 2026-10-22 |
| Venetoclax Basket Trial for High Risk Hematologic Malignancies Venetoclax, Azacitidine, Cytarabine - Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary | Phase 1 | Recruiting | Andrew E. Place, MD | 30 | 2023-03-29 | 2026-03-12 |
| Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax Venetoclax, Navitoclax, Dexamethasone - Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 35 | 2022-08-25 | 2026-10-15 |
| Nivolumab 40 mg in Combination With Chemo-Immunotherapy for Newly Diagnosed Primary Mediastinal B-Cell Lymphoma Cyclophosphamide, Doxorubicin Hydrochloride, Etoposide Phosphate - Primary Mediastinal Lymphoma | Phase 3 | Active not recruiting | National Research Center for Hematology, Russia | 60 | 2022-04-01 | 2026-10-08 |
| Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia Cyclophosphamide, Cytarabine, Daunorubicin Hydrochloride - B Acute Lymphoblastic Leukemia, Ph-Like Acute Lymphoblastic Leukemia | Phase 1 | Active not recruiting | City of Hope Medical Center | 24 | 2022-03-17 | 2026-05-28 |
| Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma Cyclophosphamide, Doxorubicin Hydrochloride, Prednisone - Diffuse Large B-Cell Lymphoma, Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Phase 1 | Active not recruiting | Yazeed Sawalha | 38 | 2021-11-16 | 2026-07-02 |
| Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Primary Mediastinal Large B-Cell Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 244 | 2021-10-05 | 2026-10-01 |
| A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Alveolar Rhabdomyosarcoma, Botryoid-Type Embryonal Rhabdomyosarcoma | Phase 3 | Active not recruiting | Children's Oncology Group | 113 | 2021-09-14 | 2026-07-30 |
| Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL) Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Acute Adult T-Cell Leukemia/Lymphoma, Adult T-Cell Leukemia/Lymphoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 30 | 2021-08-31 | 2026-10-15 |
| A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma Cyclophosphamide, Daratumumab, Doxorubicin - Plasmablastic Lymphoma, Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Early Phase 1 | Recruiting | AIDS Malignancy Consortium | 15 | 2021-05-24 | 2026-06-01 |
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Lymphoma (140) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (82) · Lymphoma, Large B-Cell, Diffuse (77) · Leukemia (66) · Burkitt Lymphoma (54) · Lymphoma, Follicular (41) · Central Nervous System Neoplasms (37) · Lymphoma, Non-Hodgkin (35) · Neuroblastoma (35) · Lymphoma, Mantle-Cell (32) · Lymphoma, Large-Cell, Immunoblastic (27) · Sarcoma (25) · Hodgkin Disease (24) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (20) · Lymphoma, Large-Cell, Anaplastic (18)
Children's Oncology Group (93) · National Cancer Institute (NCI) (58) · M.D. Anderson Cancer Center (18) · Children's Cancer and Leukaemia Group (17) · Memorial Sloan Kettering Cancer Center (17) · SWOG Cancer Research Network (15) · Alliance for Clinical Trials in Oncology (12) · European Organisation for Research and Treatment of Cancer - EORTC (11) · St. Jude Children's Research Hospital (9) · Eastern Cooperative Oncology Group (8) · Medical Research Council (8) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · AIDS Malignancy Consortium (6) · Societe Internationale d'Oncologie Pediatrique (6) · German High-Grade Non-Hodgkin's Lymphoma Study Group (5)
United States (313) · Canada (108) · Australia (83) · United Kingdom (69) · Puerto Rico (64) · Switzerland (61) · New Zealand (38) · Netherlands (37) · Germany (32) · France (28) · Italy (27) · Belgium (23) · Sweden (16) · Ireland (15) · Austria (14)
Elias Jabbour (6) · Frank Berthold, MD (5) · Ann Barrett (4) · Lode J. Swinnen, MD (4) · Mary P. Gerrard, MBChB, FRCP, FRCPCH (4) · Oliver W. Press, MD, PhD (4) · Andrew David J. Pearson, MD, FRCP, DCh (3) · Dieter Koerholz, MD (3) · Janice A. Kohler, MD, FRCP (3) · Jonathan L. Finlay, MB, ChB (3) · Leo I. Gordon, MD (3) · Michael G.M. Pfreundschuh, MD (3) · Pierre Soubeyran, MD, PhD (3) · Ruth Pettengell, MD (3) · Sandra J. Horning, MD (3)
PMID 41671463, PMID 37505794, PMID 37890117, PMID 38603649, PMID 39121442, PMID 23007406, PMID 33242441, PMID 35622074, PMID 38446568, PMID 22337718, PMID 23233662, PMID 24970932, PMID 26590194, PMID 26913693, PMID 27465021, PMID 29284596, PMID 32589970, PMID 33395032, PMID 33496745, PMID 34028986, PMID 34048072, PMID 34634256, PMID 35731991, PMID 36603187, PMID 39058968, PMID 40135712, PMID 40315406, PMID 42085640, PMID 10463285, PMID 10499612, PMID 10820362, PMID 11426549, PMID 11464889, PMID 11586105, PMID 11600602, PMID 11835236, PMID 11857322, PMID 11904735, PMID 12101494, PMID 12111109, PMID 12153596, PMID 12239143, PMID 12525516, PMID 12694250, PMID 12697884, PMID 12738671, PMID 12780755, PMID 12932669, PMID 14508361, PMID 15001263
U10CA098543 (44), U10CA180886 (42), U10CA032102 (19), U10CA031946 (9), U10CA021115 (8), U10CA180888 (6), U01CA070019 (5), UM1CA121947 (5), P30CA016672 (4), P30CA036727 (4), U10CA180820 (4), P30CA015704 (3), P30CA060553 (3), U10CA180821 (3), 2004 (2)