Tranexamic acid injection: Clinical Trials

39 trials of Tranexamic acid injection, newest first

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21 completed, 12 unknown, 3 recruiting, 1 not yet recruiting. 17 Not applicable, 10 Phase 4, 6 Phase 3, 4 Early Phase 1, 1 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable17Completed 9, Unknown 7, Recruiting 1
Phase 410Completed 7, Recruiting 2, Unknown 1
Phase 36Completed 3, Not yet recruiting 1, Unknown 1, Withdrawn 1
Early Phase 14Unknown 3, Terminated 1
Phase 11Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study
Tranexamic acid injection - Brain Injuries, Traumatic, Wounds and Injury
Phase 3Not yet recruitingDaniel Nishijima, MD, MAS20002026-10-012025-12-15
The Effect of Local and Systemic Tranexamic Acid on Edema and Ecchymosis in Orbital Surgery
Tranexamic acid injection, Tranexamic Acid in NaCl,Iso-Os 1,000 Mg/100 mL (10 Mg/mL) INTRAVEN INTRAVENOUS SOLUTION, PIGGYBACK (ML), normal saline - injection - Orbital Edema, Orbital Ecchymosis
Phase 4RecruitingMontefiore Medical Center1502024-10-072025-12-16
Comparing Intramyometrial Tranexamic Acid and Oxytocin for Blood Loss in Cesarean Section
Tranexamic acid injection, Oxytocin - Cesarean Section Complications, Tranexamic Acid
Phase 3UnknownCairo University1502024-10-012024-09-05
Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery.
Tranexamic acid injection, Placebo - Post Partum Hemorrhage
Not applicableRecruitingAligarh Muslim University3002024-10-012024-10-24
Different Methods of Tranexamic Acid Application in Controlling Peri Operative Bleeding in Gynecomastia Surgery
Tranexamic acid injection - Pharmacological-Aggravated Urticaria
Early Phase 1UnknownAssiut University502024-07-202024-07-19
Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid
Tranexamic acid injection - Refractory Melasma
Not applicableUnknownEgymedicalpedia452024-06-012024-07-26
Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy
Concentrated secretome Injection 2mL, Tranexamic acid injection, Triple Combination Cream - Melasma
Not applicableUnknownDr.dr.Irma Bernadette, SpKK (K)902024-02-132024-07-24
Tranexamic Acid in Patients for Caesarian Delivery.
Tranexamic acid injection - Postpartum Hemorrhage, Cesarean Section Complications
Not applicableCompletedDow University of Health Sciences5722023-03-202025-02-04
Effect on Post-operative Pain of Tranexamic Acid Injection During Shoulder Surgery
Tranexamic acid injection, Placebo - Shoulder Disease
Phase 3CompletedElsan2202023-02-242026-04-23
Tranexamic Acid as an Intervention in Abruptio Placenta
Tranexamic acid injection, Dextrose 5% in water - Vaginal Bleeding, Prolonged Pregnancy
Not applicableCompletedHawler Medical University1162023-01-102025-11-19
TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality
Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane - Rhinosinusitis Chronic, Sinus Cancer
Not applicableUnknownOur Lady of the Lake Hospital1002023-01-012023-03-23
Tranexamic Acid as an Intervention in Placenta Previa
Tranexamic acid injection, Glucose water 5% - Interventional Drug in Placenta Previa
Not applicableCompletedHawler Medical University1462022-12-102025-01-27
Indian Trial of Tranexamic Acid in Spontaneous Intracerebral Haemorrhage
Tranexamic acid injection - Intracerebral Hemorrhagic Stroke
Phase 4RecruitingChristian Medical College and Hospital, Ludhiana, India34002022-08-302026-01-22
A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery
Tranexamic acid injection, No additional irrigation - Hematoma Postoperative
Phase 4CompletedUniversity of Michigan1072022-08-152025-11-26
Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient
Tranexamic acid injection, normal saline - Blood Loss, Surgical
Early Phase 1UnknownShaukat Khanum Memorial Cancer Hospital & Research Centre422022-04-062023-03-28
Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty
Tranexamic acid injection, apply the QCG, apply surgical gauze - Total Blood Loss, Arthropathy of Knee Joint
Phase 4CompletedChang Gung Memorial Hospital1402022-03-162026-07-22
Effectiveness Of Tranexamic Acıd Application Wıth Different Doses On Bleeding, Edema And Physician Comfort In Orthognathıc Surgery Patients
Tranexamic acid injection, Saline - Tranexamic Acid, Orthognathic Surgery
Not applicableCompletedBezmialem Vakif University602022-03-012024-03-08
A Randomized Comparison of Two Doses of Tranexamic Acid in Open-Heart Surgery
Tranexamic acid injection - Drug Use
Not applicableCompletedShahid Gangalal National Heart Centre1202022-02-012023-04-25
Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.
Tranexamic acid injection, Saline - Ewing Sarcoma of Bone, Osteosarcoma
Phase 3CompletedChildren's Cancer Hospital Egypt 57357482021-08-022024-02-07
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery
Tranexamic acid injection, Local anesthetic control - Edema, Ecchymosis; Eyelid
Phase 4UnknownConsultants in Ophthalmic and Facial Plastics Surgery502021-08-012021-07-06

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Conditions studied

Postpartum Hemorrhage (6)  ·  Melanosis (4)  ·  Hemorrhage (3)  ·  Postoperative Hemorrhage (3)  ·  Blood Loss, Surgical (2)  ·  Edema (2)  ·  Exsanguination (2)  ·  Pain, Postoperative (2)  ·  Wounds and Injuries (2)  ·  Abruptio Placentae (1)  ·  Accidental Injuries (1)  ·  Brain Injuries (1)  ·  Brain Injuries, Traumatic (1)  ·  Contusions (1)  ·  Ecchymosis (1)

Sponsors

Hawler Medical University (3)  ·  Assiut University (2)  ·  Cairo University (2)  ·  Universitas Indonesia (2)  ·  Aligarh Muslim University (1)  ·  Benha University (1)  ·  Bezmialem Vakif University (1)  ·  Chang Gung Memorial Hospital (1)  ·  Children's Cancer Hospital Egypt 57357 (1)  ·  Christian Medical College and Hospital, Ludhiana, India (1)  ·  Combined Military Hospital Abbottabad (1)  ·  Consultants in Ophthalmic and Facial Plastics Surgery (1)  ·  Daniel Nishijima, MD, MAS (1)  ·  Dow University of Health Sciences (1)  ·  Dr.dr.Irma Bernadette, SpKK (K) (1)

Countries

Egypt (6)  ·  United States (6)  ·  India (3)  ·  Indonesia (3)  ·  Iraq (3)  ·  Pakistan (3)  ·  China (2)  ·  Belgium (1)  ·  France (1)  ·  Malaysia (1)  ·  Nepal (1)  ·  Poland (1)  ·  Taiwan (1)  ·  Turkey (Türkiye) (1)  ·  Zimbabwe (1)

Top investigators

Ahmed N Afifi, MD (1)  ·  Ahmed N Shaker, MD (1)  ·  Anne Barmettler (1)  ·  Ari F Syam, Dr, MD (1)  ·  Ariana Jawad, professor (1)  ·  Chipo Gwanzura, MD (1)  ·  Chro S. Hassan, MBChB (1)  ·  Daniel K Nishijima, MD, MAS (1)  ·  Diaa Eldin Taha, MD (1)  ·  Edwin Wilkins, MD (1)  ·  Gurleen Kaur, MD (1)  ·  Haisong Lu (1)  ·  Hongwen Ji, MD (1)  ·  Jeyaraj D Pandian, MD DM (1)

Results publications

PMID 21215592, PMID 21439633, PMID 26985786, PMID 30233155, PMID 30322584, PMID 31271691, PMID 31299040, PMID 31870749, PMID 31962259, PMID 32278572, PMID 33475421, PMID 37106343, PMID 37882229, PMID 3791738, PMID 38214552, PMID 39633570, PMID 41180854

NIH funding

D43TW009343 (1)