5 completed, 1 recruiting, 1 terminated. 7 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
Follow Tirapazamine: new trials by email Literature Review of Tirapazamine trials Research Report on Tirapazamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluate the Effect of Tirazamine on Primary Liver Cancer. tirapazamine, Transarterial Embolization, TACE - Hepato Cellular Carcinoma (HCC) | Phase 1 / Phase 2 | Terminated | Zhejiang Raygene Pharmaceuticals Co., Ltd | 16 | 2021-05-14 | 2025-02-27 |
| Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer Tirapazamine, Conventional Transarterial Embolization (TAE) - Hepatocellular Carcinoma, Gastrointestinal Cancer Metastatic | Phase 1 / Phase 2 | Recruiting | Teclison Ltd. | 25 | 2014-09-01 | 2026-04-20 |
| Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer cisplatin, tirapazamine, brachytherapy - Cervical Cancer | Phase 1 | Completed | Peter MacCallum Cancer Centre, Australia | 22 | 2004-12-01 | 2013-06-26 |
| Chemotherapy, Tirapazamine, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer carboplatin, paclitaxel, tirapazamine - Lung Cancer | Phase 1 | Completed | California Cancer Consortium | 30 | 2002-03-01 | 2009-02-09 |
| S0004: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-stage Small Cell Lung Cancer cisplatin, etoposide, tirapazamine - Lung Cancer | Phase 1 | Completed | SWOG Cancer Research Network | 30 | 2000-10-01 | 2012-10-04 |
| Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors carboplatin, paclitaxel, tirapazamine - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | City of Hope Medical Center | 44 | 2000-03-01 | 2015-06-08 |
| Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors filgrastim, cyclophosphamide, tirapazamine - Unspecified Childhood Solid Tumor, Protocol Specific | Phase 1 | Completed | National Cancer Institute (NCI) | 12 | 1998-08-01 | 2013-02-05 |
Carcinoma, Hepatocellular (2) · Lung Neoplasms (2) · Adenocarcinoma of Lung (1) · Carcinoma, Non-Small-Cell Lung (1) · Hypoxia (1) · Neuroendocrine Tumors (1) · Uterine Cervical Neoplasms (1)
California Cancer Consortium (1) · City of Hope Medical Center (1) · National Cancer Institute (NCI) (1) · Peter MacCallum Cancer Centre, Australia (1) · SWOG Cancer Research Network (1) · Teclison Ltd. (1) · Zhejiang Raygene Pharmaceuticals Co., Ltd (1)
United States (5) · Canada (2) · Australia (1) · China (1)
Caifang Ni, M.D (1) · Danny Rischin, MD (1) · Derick H. Lau, MD (1) · Michael Soulen, MD (1) · Quynh-Thu X. Le, MD (1) · Stephen Shibata, MD (1) · Victor Aquino, MD (1)
P30CA033572 (1), U01CA062505 (1), U10CA032102 (1)