4 completed. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
Follow Thymidine: new trials by email Literature Review of Thymidine trials Research Report on Thymidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study Irinotecan, Bevacizumab, Trifluridine and Tipiracil Hydrochloride - Advanced Colorectal Carcinoma, Metastatic Colon Adenocarcinoma | Phase 2 | Completed | Roswell Park Cancer Institute | 42 | 2019-12-27 | 2026-02-10 |
| Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma Trifluridine and Tipiracil Hydrochloride, Oxaliplatin - Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 | Completed | Roswell Park Cancer Institute | 22 | 2019-12-20 | 2025-04-29 |
| An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency doxecitine and doxribtimine - Thymidine Kinase 2 Deficiency | Phase 2 | Completed | UCB BIOSCIENCES, Inc. | 47 | 2019-07-05 | 2026-09-08 |
| Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity ribose, thymidine, uridine - 5'-Nucleotidase Syndrome | Phase 2 | Completed | National Center for Research Resources (NCRR) | 1995-03-01 | 2005-06-24 |
5-Nucleotidase syndrome (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Metabolism, Inborn Errors (1) · Mitochondrial Diseases (1) · Muscle Weakness (1) · Muscular Atrophy (1) · Rare Diseases (1) · Rectal Neoplasms (1)
Roswell Park Cancer Institute (2) · National Center for Research Resources (NCRR) (1) · UCB BIOSCIENCES, Inc. (1)
United States (3) · Israel (1) · Spain (1)
Alice L. Yu (1) · Christos Fountilas, MD (1) · Christos Fountzilas, MD (1)
PMID 33246973, PMID 39244627, PMID 40200573
2018 (1), 2023 (1)