7 completed, 1 unknown. 6 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
Follow Theobromine: new trials by email Literature Review of Theobromine trials Research Report on Theobromine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Dentin Hypersensitivity Using Different Desensitizing Agents Theobromine, Remin Pro - Dentin Sensitivity | Not applicable | Unknown | Al-Azhar University | 30 | 2019-08-01 | 2020-04-10 |
| Theobromine, Vascular Function and Intestinal apoA-I Production Theobromine, Placebo drink - Cardiovascular Disease | Not applicable | Completed | Maastricht University Medical Center | 48 | 2014-06-01 | 2015-09-07 |
| The Effects of Fat and Theobromine on apoA-I Fat milkshake, Theobromine - Cardiovascular Diseases | Not applicable | Completed | Maastricht University Medical Center | 10 | 2014-02-01 | 2014-08-05 |
| Study of the Safety and Effectiveness of BC1036 Capsules to Treat Frequent Long-Term Cough BC1036 - Cough | Phase 3 | Completed | Respicopea Limited | 288 | 2012-07-01 | 2013-08-02 |
| The Acute Effect of 2 Different Serving Regimens of Theobromine on Physiological Effects Theobromine, Placebo - Cardiovascular Diseases | Not applicable | Completed | Unilever R&D | 12 | 2012-02-01 | 2012-12-03 |
| The Effect of Theobromine on Blood Lipid Parameters in Healthy Subjects Theobromine, Cocoa, Cocoa and theobromine - Cardiovascular Diseases | Not applicable | Completed | Unilever R&D | 152 | 2010-12-01 | 2012-09-18 |
| Clinical Trial to Evaluate the Safety and Efficacy of "Theobromine Capsule" as an Antitussive in Acute Cougher Theobromine 300mg, Levodropropizine 10mg - Acute Bronchitis | Phase 3 | Completed | Ahn-Gook Pharmaceuticals Co.,Ltd | 332 | 2010-05-01 | 2011-08-15 |
| Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure theobromine, Caffeine, caffeine + theobromine - Mood | Not applicable | Completed | Unilever R&D | 24 | 2008-05-01 | 2012-02-23 |
Cardiovascular Diseases (4) · Cough (2) · Atherosclerosis (1) · Bronchiolitis Obliterans Syndrome (1) · Bronchitis (1) · Dentin Sensitivity (1)
Unilever R&D (3) · Maastricht University Medical Center (2) · Ahn-Gook Pharmaceuticals Co.,Ltd (1) · Al-Azhar University (1) · Respicopea Limited (1)
Netherlands (3) · France (2) · Egypt (1) · South Korea (1) · United Kingdom (1)
Wieneke Koppenol, MSc (2) · Alan Jackson, MB, BS (1) · Alun George, MA MBBS, DRCOG, DCH, MRCGP (1) · Alyn Morice, BA(Hons) MB.B.Chir MA FRCP (1) · Bernard Higgins, MB ChB, MRCP, MD (1) · Chris Strang, MB BS, D. Obst, RCOG M (1) · Damien McNally, MB,BCh,BAO,DRCOG,DMH,MRCGP (1) · Fan Chung, MB, BS, MD, FRCP, DSc (PI) (1) · Ian Pavord, MB BS, MRCP, FRCP, DM (1) · J Plat, Prof (1) · Jae Yeol Kim, M.D. (1) · Jogchum Plat, Prof (1) · Ki-Suck Jung, M.D. (1) · Kwan Ho Lee, M.D. (1)
PMID 23595874, PMID 28645636, PMID 28839984, PMID 29330660, PMID 42834376