2 recruiting, 2 terminated, 1 completed. 4 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 2, Terminated 2 |
| Early Phase 1 | 1 | Completed 1 |
Follow Td vaccine: new trials by email Literature Review of Td vaccine trials Research Report on Td vaccine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma TTRNA-DC vaccines with GM-CSF, TTRNA-xALT, Td vaccine - Recurrent Group 3 Medulloblastoma, Recurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma | Phase 1 | Recruiting | University of Florida | 12 | 2025-05-05 | 2026-08-07 |
| ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients TTRNA-DC vaccines with GM-CSF, Autologous Hematopoietic Stem cells (HSCs), TTRNA-xALT - Recurrent Oligodendroglioma, Progressive Oligodendroglioma | Phase 1 | Recruiting | University of Florida | 12 | 2024-09-19 | 2026-05-27 |
| Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas TTRNA-DC vaccines with GM-CSF, Dose-intensified TMZ, Autologous Hematopoietic Stem cells (HSCs) - Malignant Glioma, High Grade Glioma | Phase 1 | Terminated | University of Florida | 18 | 2018-08-27 | 2026-04-23 |
| Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) TTRNA-DC vaccines with GM-CSF, TTRNA-xALT, Cyclophosphamide + Fludarabine Lymphodepletive Conditioning - Diffuse Intrinsic Pontine Glioma (DIPG), Brain Stem Glioma | Phase 1 | Terminated | University of Florida | 11 | 2018-07-17 | 2025-10-29 |
| Entolimod, an Adjuvant for Vaccine Augmentation Entolimod, Td Vaccine - Substance Use Disorders | Early Phase 1 | Completed | Baylor College of Medicine | 40 | 2017-12-08 | 2020-09-01 |
Brain Neoplasms (2) · Diffuse Intrinsic Pontine Glioma (1) · Glioma (1) · Influenza, Human (1) · Medulloblastoma (1) · Oligodendroglioma (1) · Substance-Related Disorders (1) · Xanthomatosis, Cerebrotendinous (1)
University of Florida (4) · Baylor College of Medicine (1)
United States (5)
Duane Mitchell, MD, PhD (3) · Elias Sayour, MD, PhD (2) · Ashley Ghiaseddin, MD (1) · John Ligon, MD (1) · Thomas Kosten, MD (1)
R01CA195563 (1)