9 completed, 3 terminated. 10 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 8, Terminated 2 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
Follow talampanel: new trials by email Literature Review of talampanel trials Research Report on talampanel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1 Study to Investigate the Effects of Talampanel on the Heart Rhythm Talampanel, Moxifloxacin, Placebo - Healthy | Phase 1 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 135 | 2009-10-01 | 2010-04-07 |
| Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS) Talampanel - Amyotrophic Lateral Sclerosis | Phase 2 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 446 | 2009-09-01 | 2013-08-26 |
| A Study to Investigate the Absorption, Metabolism and Excretion of Talampanel Talampanel (non-radiolabeled), [14C] Talampanel - Healthy | Phase 1 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 10 | 2009-05-01 | 2009-09-16 |
| Talampanel for Amyotrophic Lateral Sclerosis (ALS) Talampanel, placebo - ALS | Phase 2 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 559 | 2008-09-01 | 2011-10-21 |
| Effects of Talampanel on Patients With Advanced Parkinson's Disease talampanel - Dyskinesias, Parkinson Disease | Phase 1 / Phase 2 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 22 | 2006-12-01 | 2011-04-13 |
| Safety and Efficacy of Talampanel in Glioblastoma Multiforme Talampanel, Radiation Therapy (RT) 5 days a week +, temozolomide(TMZ) 75mg - Glioblastoma Multiforme | Phase 2 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 72 | 2005-12-01 | 2016-05-19 |
| Talampanel to Treat Parkinson's Disease IV Levodopa, Talampanel - Parkinson Disease | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 40 | 2005-04-01 | 2008-03-04 |
| Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas Talampanel - Glioblastoma Multiforme, Anaplastic Astrocytoma | Phase 2 | Terminated | Teva Branded Pharmaceutical Products R&D, Inc. | 30 | 2003-07-01 | 2011-05-23 |
| Talampanel in Treating Patients With Recurrent High-Grade Glioma talampanel - Brain and Central Nervous System Tumors | Phase 2 | Completed | National Institutes of Health Clinical Center (CC) | 2003-06-01 | 2012-03-08 | |
| Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity Talampanel - Healthy | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 25 | 2003-04-01 | 2008-03-04 |
| Multicenter Trial for Adults With Partial Seizures Talampanel, Placebo - Epilepsy | Phase 2 | Completed | Teva Branded Pharmaceutical Products R&D, Inc. | 190 | 2002-01-01 | 2011-03-17 |
| Study of LY300164 for the Treatment of Parkinson's Disease LY300164 - Dyskinesias, Parkinson Disease | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 20 | 2000-02-01 | 2008-03-04 |
Dyskinesias (3) · Glioblastoma (3) · Parkinson Disease (3) · Astrocytoma (2) · Epilepsy (2) · Oligodendroglioma (2) · Amyotrophic Lateral Sclerosis (1) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Glioma (1) · Gliosarcoma (1) · Movement Disorders (1)
Teva Branded Pharmaceutical Products R&D, Inc. (8) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · National Institutes of Health Clinical Center (CC) (1)
United States (7) · Belgium (1) · Canada (1) · France (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · Netherlands (1) · Spain (1)
Craig R Sprenger, MD (1) · Howard A. Fine, MD (1) · Nicholas M Siebers, MD (1)