9 completed, 1 terminated. 6 Phase 3, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow this drug Literature Review of Succinic Acid trials Research Report on Succinic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cytoflavin in the Complex Rehabilitation of Stroke Patients Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid), Placebo - Stroke | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 240 | 2023-06-30 | 2026-04-14 |
| Comparative Study of REMAXA®, Enteric-coated Tablets and REMAXOL®, Solution for Infusions, in Intrahepatic Cholestasis Remaxa, enteric-coated tablets, Remaxol, Placebo - Cholestasis, Intrahepatic | Phase 2 / Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 328 | 2023-05-27 | 2025-04-29 |
| Cytoflavin in Combination With Reperfusion in Stroke Patients Cytoflavin (succinic acid + inosine + nicotinamide + riboflavin), Control - Acute Stroke | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 200 | 2022-04-10 | 2023-03-20 | |
| Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid), Placebo - Diabetic Neuropathies | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 216 | 2020-11-25 | 2023-01-27 |
| International Trial of Efficacy of Cytoflavin in Head Trauma Cytoflavin ((Inosine + Nicotinamide + Riboflavin + Succinic Acid), Placebo - Head Trauma,Closed | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 166 | 2020-11-22 | 2025-04-18 |
| Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities Cabozantinib S-malate, Radiation Therapy - Sarcoma of the Extremity, Stage I Soft Tissue Sarcoma of the Trunk and Extremities | Phase 1 / Phase 2 | Terminated | University of Washington | 6 | 2020-06-01 | 2025-07-17 |
| Remaxol® in Mechanical Jaundice of Non-malignant Origin Remaxol (succinate + methionine + inosine + nicotinamide), Ringer's Solution - Jaundice, Obstructive | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 342 | 2017-04-03 | 2020-07-14 |
| Remaxol® in Malignant Mechanical Jaundice Remaxol®, Ringer's Solution - Jaundice; Malignant | Phase 3 | Completed | POLYSAN Scientific & Technological Pharmaceutical Company | 240 | 2017-04-03 | 2020-07-10 |
| A Pooled Analysis of the Data From Two Studies of Ammonium Succinate for Menopausal Symptoms Ammonium succinate, Placebo - Menopause Related Conditions | Completed | I.M. Sechenov First Moscow State Medical University | 227 | 2017-02-11 | 2017-10-20 | |
| Ixabepilone and Sunitinib Malate in Treating Patients With Progressive Advanced Solid Tumors Ixabepilone, Sunitinib - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | Jaime Merchan | 36 | 2008-11-01 | 2015-10-09 |
Jaundice, Obstructive (2) · Stroke (2) · Brain Concussion (1) · Brain Injuries, Traumatic (1) · Cerebral Infarction (1) · Cholestasis, Intrahepatic (1) · Craniocerebral Trauma (1) · Diabetes Mellitus (1) · Diabetic Neuropathies (1) · Head Injuries, Closed (1) · Jaundice (1) · Peripheral Nervous System Diseases (1)
POLYSAN Scientific & Technological Pharmaceutical Company (7) · I.M. Sechenov First Moscow State Medical University (1) · Jaime Merchan (1) · University of Washington (1)
Russia (8) · United States (2) · Kazakhstan (1)
Mikhail S. Bogomolov, MD, PhD (2) · Alexander V Savello, Prof (1) · Alexey Shmonin, Prof (1) · Dina R Khasanova, prof. (1) · Igor A Strokov, Prof. (1) · Irina V Kuznetsova (1) · Jaime R. Merchan, MD (1) · Lee Cranmer, MD, PhD (1) · Taras A Skoromets, Prof (1) · Tatiana V Kharitonova, MD PhD (1)