16 completed, 8 active not recruiting, 6 recruiting, 5 terminated. 42 Phase 3, 17 Phase 2.
Follow Stem Cell Transplantation: new trials by email Literature Review of Stem Cell Transplantation trials Research Report on Stem Cell Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection - Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma | Phase 2 / Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 374 | 2026-12-04 | 2026-07-08 |
| Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy Autologous Hematopoietic Stem Cell Transplantation, Best Practice, Biospecimen Collection - Anaplastic Large Cell Lymphoma, ALK-Negative, Follicular Helper T-Cell Lymphoma | Phase 3 | Recruiting | Eastern Cooperative Oncology Group | 294 | 2025-06-18 | 2026-09-14 |
| Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis Autologous Hematopoietic Stem Cell Transplantation, Biopsy, Biospecimen Collection - AL Amyloidosis | Phase 3 | Recruiting | SWOG Cancer Research Network | 338 | 2024-07-01 | 2026-05-06 |
| Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Ganglioneuroblastoma, Nodular, Neuroblastoma | Phase 3 | Recruiting | National Cancer Institute (NCI) | 478 | 2024-04-19 | 2026-10-27 |
| A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphoma Autologous Hematopoietic Stem Cell Transplantation, Bendamustine, Brentuximab Vedotin - Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma | Phase 3 | Withdrawn | National Cancer Institute (NCI) | 2023-08-10 | 2024-03-20 | |
| Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome Biospecimen Collection, Bone Marrow Aspiration, Busulfan - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 3 | Active not recruiting | Children's Oncology Group | 66 | 2023-03-15 | 2026-07-30 |
| Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS Busulfan, Cladribine, Fludarabine Phosphate - Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia | Phase 2 / Phase 3 | Recruiting | M.D. Anderson Cancer Center | 324 | 2021-10-21 | 2026-08-11 |
| A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations Allogeneic Hematopoietic Stem Cell Transplantation, Asparaginase Erwinia chrysanthemi, Biospecimen Collection - Acute Myeloid Leukemia | Phase 3 | Recruiting | Children's Oncology Group | 1400 | 2020-07-21 | 2026-09-17 |
| Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases Supportive Palliative Care, Clinical Management, Best Practice - Hematopoietic and Lymphoid Cell Neoplasm, Non-Neoplastic Hematologic and Lymphocytic Disorder | Phase 2 / Phase 3 | Terminated | Fred Hutchinson Cancer Center | 458 | 2019-08-15 | 2026-01-12 |
| Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular | Phase 3 | Recruiting | Children's Oncology Group | 750 | 2018-05-14 | 2026-08-25 |
| Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Lactobacillus plantarum strain 299, Lactobacillus plantarum strain 299v - Acute Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm | Phase 3 | Active not recruiting | Children's Oncology Group | 173 | 2018-04-30 | 2025-10-06 |
| Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspirate - Mantle Cell Lymphoma | Phase 3 | Active not recruiting | ECOG-ACRIN Cancer Research Group | 689 | 2017-11-27 | 2026-09-14 |
| Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen Hematopoietic stem cells transplantation - Acute Leukemia, Non Hodgkin Lymphoma | Phase 3 | Completed | Institut Paoli-Calmettes | 9 | 2017-09-19 | 2026-10-01 |
| Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Calaspargase Pegol, Cyclophosphamide - Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia | Phase 3 | Active not recruiting | Children's Oncology Group | 352 | 2017-08-08 | 2026-10-05 |
| Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma Autologous Bone Marrow Transplantation, Autologous Hematopoietic Stem Cell Transplantation, Carmustine - Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type, Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 94 | 2016-10-12 | 2026-07-31 |
| Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment Rituximab, Nelarabine, PEG-Asparaginase - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 3 | Completed | Goethe University | 1023 | 2016-08-01 | 2025-12-16 |
| Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Asparaginase, Blinatumomab - Recurrent B Acute Lymphoblastic Leukemia | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 669 | 2014-12-17 | 2026-10-21 |
| Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Blinatumomab - Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 488 | 2014-05-19 | 2026-09-21 |
| Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior Cytarabine consolidation, Allogeneic transplant - Acute Myeloid Leukemia | Phase 2 / Phase 3 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 10 | 2013-12-01 | 2018-08-14 |
| A Randomized Trial to Compare Busulfan + Melphalan 140 mg/m2 With Melphalan 200 mg/m2 as Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma Busulfan, Melphalan, Questionnaire - Myeloma | Phase 3 | Completed | M.D. Anderson Cancer Center | 205 | 2011-09-30 | 2020-04-21 |
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Leukemia, Myeloid, Acute (8) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Multiple Myeloma (4) · Burkitt Lymphoma (3) · Hematologic Neoplasms (3) · Myelodysplastic Syndromes (3) · Ganglioneuroblastoma (2) · Leukemia (2) · Leukemia, Biphenotypic, Acute (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Lymphohistiocytosis, Hemophagocytic (2) · Lymphoma (2) · Lymphoma, Non-Hodgkin (2) · Neuroblastoma (2) · Adrenoleukodystrophy (1)
Children's Oncology Group (8) · Masonic Cancer Center, University of Minnesota (7) · National Cancer Institute (NCI) (7) · M.D. Anderson Cancer Center (3) · Tehran University of Medical Sciences (3) · Azienda Ospedaliera San Giovanni Battista (1) · Dutch Childhood Oncology Group (1) · ECOG-ACRIN Cancer Research Group (1) · Eastern Cooperative Oncology Group (1) · European Society for Blood and Marrow Transplantation (1) · Fred Hutchinson Cancer Center (1) · Goethe University (1) · Institut Paoli-Calmettes (1) · Karolinska University Hospital (1) · National Heart Institute, Mexico (1)
United States (30) · Canada (11) · Australia (9) · Puerto Rico (7) · France (3) · Germany (3) · Iran (3) · Israel (3) · New Zealand (3) · Saudi Arabia (3) · Austria (2) · Belgium (2) · Italy (2) · Mexico (2) · Netherlands (2)
Amir Ali Hamidieh, MD (2) · Paul Orchard, MD (2) · Vaishalee P Kenkre (2) · Alyssa T Reddy (1) · Andrea Biondi (1) · Angela Smith, MD (1) · Charalambos B Andreadis (1) · Claire M Mazewski (1) · Claudio Brunstein, MD, PhD (1) · Didier Blaise (1) · Dietger Niederwieser, Prof (1) · Gregory A. Hale, M.D. (1) · Heather J Symons (1) · Ira J Dunkel (1)
PMID 20383216, PMID 21586746, PMID 22571201, PMID 22847303, PMID 28826616, PMID 28935695, PMID 30910541, PMID 32589970, PMID 32730180, PMID 32780845, PMID 33288485, PMID 33651090, PMID 33843815, PMID 34028986, PMID 35820112, PMID 36485104, PMID 37257143, PMID 38107263, PMID 38947228, PMID 39047240, PMID 39515374, PMID 40568722, PMID 42477805, PMID 42497367, PMID 42628036, PMID 42832396
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