8 completed, 2 terminated, 1 unknown. 4 Phase 1, 4 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Terminated 2 |
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow sodium stibogluconate: new trials by email Literature Review of sodium stibogluconate trials Research Report on sodium stibogluconate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study LXE408, sodium stibogluconate, Paromomycin - Primary Visceral Leishmaniasis | Phase 2 | Completed | Drugs for Neglected Diseases | 52 | 2024-03-29 | 2025-12-18 |
| Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations Sodium stibogluconate - Myelodysplastic Syndromes, Acute Myeloid Leukemia | Phase 2 | Unknown | First Affiliated Hospital of Jinan University | 5 | 2020-06-01 | 2021-06-09 |
| Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa Miltefosine, Paromomycin, Sodium stibogluconate - Visceral Leishmaniasis | Phase 3 | Completed | Drugs for Neglected Diseases | 439 | 2018-01-24 | 2024-02-29 |
| Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients Electro-thermo-coagulation, Sodium Stibogluconate, DAC N-055 - Wound Healing | Phase 2 | Completed | Waisenmedizin e. V. Promoting Access to Essential Medicine | 63 | 2010-01-01 | 2011-03-28 |
| A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis LEISH-F2 + MPL-SE, Sodium stibogluconate - Cutaneous Leishmaniasis | Phase 2 | Completed | Access to Advanced Health Institute (AAHI) | 45 | 2009-10-01 | 2013-12-11 |
| Efficacy of Radio-frequency Induced Heat (RFH)Therapy in Treatment of Cutaneous Leishmaniasis in India RFH therapy, Sodium stibogluconate - Cutaneous Leishmaniasis | Phase 4 | Completed | Sarder Patel Medical College | 100 | 2009-08-01 | 2012-09-03 |
| Phase I/II Trial of Sodium Stibogluconate in Myelodysplastic Syndrome sodium stibogluconate - Myelodysplastic Syndromes | Phase 1 | Terminated | Northwestern University | 1 | 2009-07-01 | 2013-11-08 |
| Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers recombinant interferon alfa-2b, cisplatin, sodium stibogluconate - Stage IV Melanoma | Phase 1 | Completed | Case Comprehensive Cancer Center | 22 | 2007-05-01 | 2020-07-24 |
| Sodium Stibogluconate With Interferon Alpha-2b for Patients With Advanced Malignancies Sodium Stibogluconate, Interferon Alpha-2b - Advanced Cancer, Solid Tumors | Phase 1 | Completed | M.D. Anderson Cancer Center | 33 | 2006-09-13 | 2018-11-15 |
| Sodium Stibogluconate and Interferon in Treating Patients With Advanced Solid Tumors, Lymphoma, or Myeloma recombinant interferon alfa-2b, sodium stibogluconate, SSG & interferon - Cancer | Phase 1 | Terminated | The Cleveland Clinic | 18 | 2005-10-01 | 2018-01-26 |
| Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis Sodium Stibogluconate, Paromomycin sulphate, SSG and Paromomycin sulphate - Visceral Leishmaniasis | Phase 3 | Completed | Drugs for Neglected Diseases | 1142 | 2004-11-01 | 2016-03-22 |
Melanoma (3) · Leishmaniasis, Cutaneous (2) · Leishmaniasis, Visceral (2) · Myelodysplastic Syndromes (2) · Astrocytoma (1) · Brain Neoplasms (1) · Carcinoma, Renal Cell (1) · Ependymoma (1) · Glioblastoma (1) · Glioma (1) · Glioma, Subependymal (1) · Gliosarcoma (1) · Hyperthermia (1) · Leishmaniasis (1) · Leukemia, Myeloid, Acute (1)
Drugs for Neglected Diseases (3) · Access to Advanced Health Institute (AAHI) (1) · Case Comprehensive Cancer Center (1) · First Affiliated Hospital of Jinan University (1) · M.D. Anderson Cancer Center (1) · Northwestern University (1) · Sarder Patel Medical College (1) · The Cleveland Clinic (1) · Waisenmedizin e. V. Promoting Access to Essential Medicine (1)
United States (4) · Ethiopia (3) · Kenya (2) · Sudan (2) · Uganda (2) · Afghanistan (1) · China (1) · India (1) · Peru (1)
Ernest C. Borden, MD (2) · Ahmed M Musa, MD, Prof (1) · Aung Naing, MD (1) · Elizabeth Eklund, MD (1) · Franco Piazza, MD, MPH (1) · Jane Mbui, MD (1) · Joseph Olobo, MD, Prof (1) · Manica Balasegaram (1) · Mezgebu Silamsaw, Dr (1) · Min Lu, PHD (1) · Ram A Bumb, MD (1) · Rezika Mohammed, MD (1)
PMID 21049063, PMID 22724029, PMID 25420793, PMID 35417717, PMID 36164254
P30CA043703 (1)