simtuzumab: Clinical Trials

13 trials of simtuzumab, newest first

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

8 completed, 5 terminated. 11 Phase 2, 2 Phase 1.

By phase and status

Phase	Trials	Status
Phase 2	11	Completed 6, Terminated 5
Phase 1	2	Completed 2

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3 SEL, SIM - Non-Alcoholic Steatohepatitis (NASH)	Phase 2	Completed	Gilead Sciences	72	2015-06-08	2019-06-26
Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC) Simtuzumab, Placebo - Primary Sclerosing Cholangitis (PSC)	Phase 2	Completed	Gilead Sciences	235	2013-03-04	2019-10-22
Study to Assess the Efficacy and Safety of Simtuzumab (GS-6624) in Adults With Idiopathic Pulmonary Fibrosis (IPF) Simtuzumab, Simtuzumab placebo - Idiopathic Pulmonary Fibrosis	Phase 2	Terminated	Gilead Sciences	544	2013-01-31	2017-05-30
Safety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH) Placebo, SIM - Liver Fibrosis Due to NASH	Phase 2	Terminated	Gilead Sciences	222	2012-12-05	2019-03-27
Simtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASH Placebo, SIM - Liver Fibrosis Due to NASH	Phase 2	Terminated	Gilead Sciences	259	2012-10-29	2019-03-27
Long-Term Safety Study of GS-6624 in Adults With Idiopathic Pulmonary Fibrosis (IPF) Simtuzumab - Idiopathic Pulmonary Fibrosis	Phase 2	Terminated	Gilead Sciences	34	2012-10-18	2017-04-04
Study of Simtuzumab in HIV and/or Hepatitis C- Infected Adults With Liver Fibrosis Simtuzumab - Liver Fibrosis, Hepatitis C	Phase 2	Completed	Gilead Sciences	18	2012-10-04	2019-11-05
Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma Simtuzumab, Placebo to match SIM, Leucovorin - Colorectal Cancer	Phase 2	Terminated	Gilead Sciences	266	2011-12-01	2019-04-17
Pilot Study of Simtuzumab in the Treatment of Liver Fibrosis Simtuzumab - Liver Fibrosis	Phase 2	Completed	Gilead Sciences	20	2011-11-01	2014-02-03
A Study to Evaluate the Efficacy and Safety of Simtuzumab Combined With Gemcitabine for Metastatic Pancreatic Adenocarcinoma Simtuzumab, Gemcitabine, Placebo to match simtuzumab - Pancreatic Cancer	Phase 2	Completed	Gilead Sciences	250	2011-11-01	2015-03-10
Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia Myelofibrosis Simtuzumab, Ruxolitinib - Myelofibrosis	Phase 2	Completed	Gilead Sciences	54	2011-06-30	2020-07-01
A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis GS-6624 - Idiopathic Pulmonary Fibrosis	Phase 1	Completed	Gilead Sciences	48	2010-12-01	2015-07-09
First-in-human Study of AB0024 to Evaluate Safety and Tolerability in Adults With Advanced Solid Tumors AB0024 - Neoplasms	Phase 1	Completed	Gilead Sciences	32	2010-06-01	2012-05-03

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