11 completed, 1 unknown, 1 withdrawn. 6 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 6 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Silicon Dioxide: new trials by email Literature Review of Silicon Dioxide trials Research Report on Silicon Dioxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NBMI Treatment in Patients With Mercury Toxicity (N1, N3-bis(2- mercaptoethyl)isophthalamide), Excipients microcrystalline cellulose, silica and magnesium stearate - Mercury Poisoning | Phase 2 / Phase 3 | Unknown | EmeraMed | 116 | 2023-11-22 | 2024-03-12 |
| Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men, Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men - Body Composition, Lean Body Mass | Not applicable | Completed | University of Southern Denmark | 80 | 2023-09-15 | 2026-05-05 |
| A Clinical Study to Assess the Safety and Effectiveness of Plant-based Biotin and Plant Based Biotin with Silica in Healthy Human Subjects with Complaints of Hair Fall, Thin, Dry, & Brittle Hair, and Dry Skin Placebo, Botanical extract of standardized biotin, Botanical extract of standardised biotin with silica - Hair Falling, Thin Hair | Not applicable | Completed | NovoBliss Research Pvt Ltd | 105 | 2023-08-22 | 2025-03-03 |
| A Study to Evaluate the Efficacy and Safety of ORMD-0801 (Oral Insulin) in Patients With Type 2 Diabetes Mellitus Cohort A: ORMD-0801, Placebo oral capsule, Cohort B: ORMD-0801 - T2DM (Type 2 Diabetes Mellitus) | Phase 2 | Completed | Oramed, Ltd. | 373 | 2018-05-29 | 2022-11-08 |
| Impact of Oral Probiotic Blend on Pregnancy Outcome capsule containing a probiotic blend of 5 different Lactobacilli, capsule containing Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, but no probiotics. - Gestational Diabetes Mellitus in Pregnancy | Not applicable | Completed | i-Health, Inc. | 170 | 2018-04-05 | 2021-02-09 |
| Probiotics for Quality of Life in Autism Spectrum Disorders Maltose (placebo), Visbiome Extra Strength - Autism Spectrum Disorders, Anxiety | Early Phase 1 | Completed | Ohio State University | 13 | 2016-08-01 | 2020-02-05 |
| Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme arginine in powder form, Silica and cellulose placebo powder - Glioblastoma Multiforme | Phase 1 | Completed | Inova Health Care Services | 1 | 2014-03-01 | 2019-09-16 |
| Investigation of the Acute Cognitive, Mood and Autonomic Effects of Hops in Healthy Participants Hops Extract, Placebo (silica) - Mood Modulation, Modulation of Cognition | Not applicable | Completed | Northumbria University | 150 | 2011-06-01 | 2012-06-25 |
| Cerebral Blood Flow Effects of Resveratrol and Piperine in Humans Trans- resveratrol, Placebo (silica) - Healthy | Not applicable | Completed | Northumbria University | 23 | 2010-04-01 | 2011-04-08 |
| To Investigate the Clinical Efficacy of an Experimental Toothpaste isopropylmethylphenol and Fluoride, Fluoride and Silica - Gingivitis | Phase 1 | Withdrawn | GlaxoSmithKline | 2009-12-09 | 2018-07-16 | |
| Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Sodium fluoride / silica and carbopol, 0.5g, Sodium fluoride / silica and carbopol, 1.5g, Fluoride free dentifrice - Dental Caries | Phase 4 | Completed | GlaxoSmithKline | 65 | 2009-01-01 | 2018-02-07 |
| The Efficacy of a Toothpaste to Reduce Sensitivity Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride - Dentin Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 626 | 2008-09-01 | 2012-03-07 |
| The Cognitive and Cerebral Blood Flow Effects of Resveratrol Trans- resveratrol, Placebo (silica) - Cognitive and Cerebral Blood Flow Effects of Resveratrol | Not applicable | Completed | Northumbria University | 24 | 2008-06-01 | 2012-05-23 |
Alopecia (1) · Anxiety Disorders (1) · Autism Spectrum Disorder (1) · Dental Caries (1) · Dentin Sensitivity (1) · Diabetes Mellitus, Type 2 (1) · Gingivitis (1) · Glioblastoma (1) · Mercury Poisoning (1) · Plaque, Amyloid (1)
Northumbria University (3) · GlaxoSmithKline (2) · Colgate Palmolive (1) · EmeraMed (1) · Inova Health Care Services (1) · NovoBliss Research Pvt Ltd (1) · Ohio State University (1) · Oramed, Ltd. (1) · University of Southern Denmark (1) · i-Health, Inc. (1)
United States (5) · United Kingdom (3) · Colombia (1) · Denmark (1) · Germany (1) · India (1)
Crystal Haskell (2) · Allen Waziri, MD (1) · Andres Cadena-Bonfanti, MD (1) · Augusto Elias, DDS (1) · Christiane Laue, MD (1) · Dr Nayan K Patel (1) · Emma L Wightman (1) · Eugene Arnold, MD (1) · Joel M Neutel, M. D. (1)