7 unknown, 3 completed, 3 not yet recruiting, 3 recruiting. 5 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Not yet recruiting 2, Completed 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Sequence Analysis, RNA: new trials by email Literature Review of Sequence Analysis, RNA trials Research Report on Sequence Analysis, RNA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetic Investigation of Cancer Predisposition DNA or RNA Sequencing - Genetic Predisposition, Cancer | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 100 | 2026-10-01 | 2026-01-06 | |
| The NorCUP Trial: Improving Prognosis and Personalized Treatment in Cancer of Unknown Primary (CUP) Comprehensive molecular profiling - Cancer of Unknown Primary Site | Not applicable | Not yet recruiting | Haukeland University Hospital | 350 | 2026-01-01 | 2026-01-26 |
| Characterization of EVs (Extracellular Vesicles)/miRNAs (microRNAs) From Human Follicular Fluid Isolation of EVs + RNA sequencing - Extracellular Vesicles | Not applicable | Not yet recruiting | University Hospital, Ghent | 14 | 2025-09-01 | 2025-08-29 |
| RNA to the RESCUE: Evaluation to Assess the Clinical Utility of RNA Sequencing in Establishing a Genetic Diagnosis or Adjudicating a Previously Established Genetic Diagnosis. RNA sequencing - Genetic Conditions, Genetic Disorders | Enrolling by invitation | University of California, San Francisco | 100 | 2025-08-06 | 2026-10-02 | |
| Understanding the Transition from Normal Melanocytes to Nevus to Melanoma Methylomics, RNA sequencing, Spatial transcriptomics - Congenital Melanocytic Nevi, Melanoma, Skin | Recruiting | Fundacion Clinic per a la Recerca Biomédica | 100 | 2024-01-01 | 2025-02-27 | |
| Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis RNA sequencing - Amyotrophic Lateral Sclerosis | Recruiting | Centre Hospitalier Universitaire de Nīmes | 192 | 2023-11-22 | 2025-05-20 | |
| Biomarker Analysis of Tislelizumab Combined With Chemotherapy for Perioperative Treatment of G/GEJ Adenocarcinoma DNA panel and RNA Sequencing - Locally Advanced Gastric Adenocarcinoma, PD-1 | Completed | Xijing Hospital | 28 | 2022-07-18 | 2025-12-04 | |
| Gene Expression Changes of Brain Tissue in Human Temporal Lobe Epilepsy With Hippocampal Sclerosis RNA sequencing - Epilepsy, Hippocampal Sclerosis | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 10 | 2021-04-19 | 2026-04-27 | |
| Guided Treatment Based on Mini-PDX in Metastatic Triple Negative Breast Cancer Personalized treatment guided by mini-PDX and RNA sequencing, Nab paclitaxel, Eribulin - Triple Negative Breast Cancer | Phase 2 | Unknown | Fudan University | 100 | 2021-02-01 | 2022-04-20 |
| Molecular Analysis of Diabetic Kidney Disease Biopsies RNA sequencing - Diabetic Nephropathies, Kidney Disease, Chronic | Unknown | Unity Health Toronto | 500 | 2019-07-01 | 2021-04-30 | |
| Interest of High-throughput Sequencing of RNAs for the Diagnosis of Heterogeneous Genetic Diseases RNA sequencing - DNA Sequencing, Diagnosis of Genetic Diseases of Heterogeneous Origin | Unknown | University Hospital, Strasbourg, France | 15 | 2019-06-01 | 2019-06-03 | |
| Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial, Spirometry, RNA Sequencing - Sarcoidosis, Pulmonary, Sarcoidosis Lung | Phase 1 | Completed | Oregon Health and Science University | 5 | 2019-05-15 | 2022-02-18 |
| RNA Sequencing Analysis in Large Vessel Occlusion Stroke DATA Bank mechanical thrombectomy - Stroke, Acute, Thrombosis | Not applicable | Unknown | Society of Minimally Invasive Neurological Therapeutic Procedures | 370 | 2018-01-01 | 2018-04-06 |
| Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy RNA sequencing, Transcriptome analysis, target drug with the score above 0,1 - Cancer | Unknown | OmicsWay Corp. | 200 | 2017-10-17 | 2021-09-14 | |
| Molecular Pathway Activation Markers Predicting Efficacy of Trastuzumab Therapy for HER2-positive Breast Cancer RNA sequencing, Transcriptome analysis, Trastuzumab - HER2-positive Breast Cancer | Unknown | OmicsWay Corp. | 40 | 2017-10-01 | 2021-09-14 | |
| Genomic and Proteomic Study of Richter Syndrome (CGPSR) Whole exome sequencing., RNA sequencing, Mass spectrometry - Richter Syndrome | Unknown | Central Hospital, Nancy, France | 170 | 2017-09-06 | 2023-03-24 | |
| TOlerance MOlecular and Genome-wide Studies With Renal Allograft Recipient Material High throughput DNA and RNA sequencing - Kidney Transplantation | Not applicable | Completed | Université Libre de Bruxelles | 18 | 2015-08-22 | 2021-11-18 |
| Multi-layer Data to Improve Diagnosis, Predict Therapy Resistance and Suggest Targeted Therapies in HGSOC WGS and RNA sequencing, circulating tumor DNA (ctDNA), FDG PET/CT imaging - High Grade Ovarian Serous Adenocarcinoma, High Grade Serous Carcinoma | Not applicable | Recruiting | Turku University Hospital | 200 | 2012-02-01 | 2025-01-16 |
Neoplasms (2) · Amyotrophic Lateral Sclerosis (1) · Breast Neoplasms (1) · Diabetic Nephropathies (1) · Disease (1) · Epilepsy (1) · Genetic Diseases, Inborn (1) · Genetic Predisposition to Disease (1) · Hippocampal Sclerosis (1) · Melanoma (1) · Neoplasms, Unknown Primary (1) · Nevi and Melanomas (1) · Ovarian Neoplasms (1) · Renal Insufficiency, Chronic (1) · Sarcoidosis (1)
OmicsWay Corp. (2) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire de Nīmes (1) · Fudan University (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Haukeland University Hospital (1) · Oregon Health and Science University (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Society of Minimally Invasive Neurological Therapeutic Procedures (1) · The University of Texas Health Science Center at San Antonio (1) · Turku University Hospital (1) · Unity Health Toronto (1) · University Hospital, Ghent (1) · University Hospital, Strasbourg, France (1) · University of California, San Francisco (1)
United States (5) · France (4) · China (3) · Russia (2) · Belgium (1) · Canada (1) · Egypt (1) · Finland (1) · Norway (1) · Spain (1)
Anton A Buzdin, Ph.D., D.Sc (1) · Claire Guissart (1) · Jim Rosenbaum, MD (1) · Johanna Hynninen, MD, PhD (1) · Julien Broseus, MD, PhD (1) · Kanika Bhardwaj (1) · Patricia L Dahia, MD, PhD (1) · Pierre Feugier, MD, PhD (1) · Reva Frankel (1) · Sampsa Hautaniemi, DTech, Prof (1) · Xichun Hu, M.D. (1)
PMID 10676951, PMID 18492108, PMID 20014148, PMID 21266718, PMID 21417856, PMID 21670202, PMID 22571487, PMID 23841899, PMID 24004666, PMID 24127483, PMID 33825964, PMID 34000073, PMID 37207655, PMID 37265662, PMID 40885189