4 recruiting, 2 completed, 2 unknown, 1 enrolling by invitation. 4 Phase 2, 1 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Enrolling by invitation 1, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Salvage Surgery: new trials by email Literature Review of Salvage Surgery trials Research Report on Salvage Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer Biospecimen Collection, Carboplatin, Cemiplimab - Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 180 | 2026-04-24 | 2026-10-26 |
| BRIDGE Study: Neoadjuvant Finotonlimab, Cetuximab, and Docetaxel in Resectable Recurrent HNSCC After Immunotherapy Progression Finotonlimab, Cetuximab, Docetaxel - Recurrent Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer | Phase 2 | Enrolling by invitation | Sun Yat-sen University | 42 | 2026-04-20 | 2026-06-01 |
| TC as Adjuvant Therapy After Surgery for Locally Recurrent Resectable Nasopharyngeal Carcinoma: a Single-arm Clinical Trial Toripalimab, Capecitabine, salvage surgery - Nasopharyngeal Carcinoma (NPC) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 62 | 2025-05-18 | 2025-05-23 |
| The Efficacy of Salvage Surgery in Patients With Residual Tumor After Concurrent Chemoradiation for Locally Advanced Cervical Cancer. salvage surgery - Cervical Cancer | Not applicable | Recruiting | Chongqing University Cancer Hospital | 188 | 2023-08-25 | 2023-10-10 |
| Surgical Treatment and Molecular Marker Exploration of Locally Recurrent Colorectal Cancer salvage surgery - Locally Recurrent Colorectal Cancer | Unknown | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 500 | 2023-01-30 | 2023-11-02 | |
| Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer External Beam Radiation Therapy, Intraoperative Radiation Therapy, Pembrolizumab - Head and Neck Carcinoma of Unknown Primary, Locally Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | Ohio State University Comprehensive Cancer Center | 45 | 2022-05-12 | 2026-07-24 |
| Tirelizumab Plus Surgery vs Surgery Alone for Recurrent Nasopharyngeal Carcinoma Tirelizumab, salvage surgery - Nasopharyngeal Carcinoma | Phase 2 | Unknown | Eye & ENT Hospital of Fudan University | 80 | 2021-10-20 | 2021-10-25 |
| Toripalimab Plus Surgery vs Surgery Alone for Resectable Recurrent Nasopharyngeal Carcinoma Toripalimab, salvage surgery - Nasopharyngeal Carcinoma, PD-1 | Phase 3 | Recruiting | Sun Yat-sen University | 218 | 2021-03-03 | 2021-03-04 |
| Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma salvage surgery - Recurrent Laryngeal Carcinoma | Completed | First Affiliated Hospital, Sun Yat-Sen University | 54 | 2016-06-01 | 2018-07-27 | |
| Induction Chemotherapy, Chemoradiotherapy and Surgery in Locally Advanced Gastric Cancer Patients Induction chemotherapy, Radiotherapy with concurrent chemotherapy, Salvage surgery - Gastric Cancer, Adenocarcinoma | Completed | Clinica Universidad de Navarra, Universidad de Navarra | 46 | 2013-09-01 | 2015-05-28 |
Nasopharyngeal Carcinoma (3) · Laryngeal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Adenocarcinoma (1) · Carcinoma (1) · Gastrointestinal Neoplasms (1) · Head and Neck Neoplasms (1) · Mouth Neoplasms (1) · Oropharyngeal Neoplasms (1) · Recurrence (1) · Stomach Neoplasms (1) · Uterine Cervical Neoplasms (1)
Sun Yat-sen University (3) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Chongqing University Cancer Hospital (1) · Clinica Universidad de Navarra, Universidad de Navarra (1) · Eye & ENT Hospital of Fudan University (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · National Cancer Institute (NCI) (1) · Ohio State University Comprehensive Cancer Center (1)
China (4) · United States (2) · Spain (1)
Chunyan Chen, MD, PhD (1) · Dongling Zou, PH.D (1) · Dukagjin M Blakaj, MD, PhD (1) · Genglong Liu (1) · Ming-Yuan Chen, MD, PhD (1) · Nabil F Saba (1) · Xuekui Liu, MD, PhD (1) · Zhaoxu Zheng, M.D. (1)
PMID 16971718, PMID 17008704, PMID 40413023
U10CA180868 (1)