9 recruiting, 5 active not recruiting, 1 completed, 1 unknown. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Recruiting 9, Active not recruiting 5, Completed 1, Unknown 1 |
| Phase 2 | 2 | Active not recruiting 1, Unknown 1 |
Follow SABR: new trials by email Literature Review of SABR trials Research Report on SABR
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 562 | 2027-03-09 | 2026-10-13 |
| Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial Atezolizumab, Bevacizumab, Biospecimen Collection - Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 226 | 2026-02-26 | 2026-08-17 |
| Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial Best Practice, Biospecimen Collection, Bone Metastases Treatment - Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm | Phase 3 | Active not recruiting | NRG Oncology | 280 | 2025-05-07 | 2026-08-17 |
| Total RadIoTherapy of Oligometastatic caNcerS stereotactic ablative radiotherapy - Oligometastatic Malignant Solid Neoplasm | Phase 3 | Recruiting | University of California, San Diego | 300 | 2024-11-12 | 2026-10-16 |
| SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma Antiandrogen Therapy, Biospecimen Collection, Hypofractionated Radiation Therapy - Biochemically Recurrent Prostate Carcinoma, Oligometastatic Prostate Carcinoma | Phase 3 | Active not recruiting | Mayo Clinic | 118 | 2024-04-04 | 2026-09-17 |
| Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer Biospecimen Collection, Bone Scan, Computed Tomography - Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 1500 | 2023-12-14 | 2026-10-23 |
| Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer Carboplatin, Cisplatin, Computed Tomography - Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 474 | 2023-07-12 | 2026-08-17 |
| Stereotactic Ablative Radiotherapy for OligoMetastatic Breast Cancer SABR - Breast Cancer Stage IV, Oligometastatic Disease | Phase 3 | Recruiting | Vastra Gotaland Region | 345 | 2022-09-19 | 2026-09-21 |
| A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT SBRT - Prostate Cancer | Phase 3 | Recruiting | Institute of Cancer Research, United Kingdom | 1128 | 2022-09-09 | 2024-09-19 |
| Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography - Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 804 | 2020-10-08 | 2026-08-19 |
| Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer Atezolizumab, Biospecimen Collection, Computed Tomography - Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 417 | 2020-08-13 | 2026-10-27 |
| Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration - Stage II Prostate Adenocarcinoma AJCC v7 | Phase 3 | Active not recruiting | NRG Oncology | 698 | 2018-02-01 | 2026-10-29 |
| Stereotactic Body Radiotherapy for the Treatment of OPD SBRT, TKI - NSCLC | Phase 2 / Phase 3 | Active not recruiting | Institute of Cancer Research, United Kingdom | 113 | 2017-11-27 | 2026-11-05 |
| Conventional Care Versus Radioablation (Stereotactic Body Radiotherapy) for Extracranial Oligometastases SBRT, Standard of Care - Prostate Cancer, Breast Cancer | Phase 2 / Phase 3 | Unknown | Royal Marsden NHS Foundation Trust | 245 | 2016-11-01 | 2019-08-21 |
| JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer Lung Surgery, Radiation therapy - Non-Small Cell Lung Cancer | Phase 3 | Recruiting | University of Texas Southwestern Medical Center | 272 | 2015-07-01 | 2026-04-16 |
| Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer Sorafenib, stereotactic body radiation therapy - Adult Primary Hepatocellular Carcinoma, Advanced Adult Primary Liver Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 193 | 2013-04-01 | 2026-01-28 |
Prostatic Neoplasms (5) · Carcinoma, Non-Small-Cell Lung (3) · Breast Neoplasms (2) · Carcinoma, Hepatocellular (2) · Lung Neoplasms (2) · Neoplasm Metastasis (1)
NRG Oncology (5) · Institute of Cancer Research, United Kingdom (2) · ECOG-ACRIN Cancer Research Group (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · Radiation Therapy Oncology Group (1) · Royal Marsden NHS Foundation Trust (1) · SWOG Cancer Research Network (1) · University of California, San Diego (1) · University of Texas Southwestern Medical Center (1) · Vastra Gotaland Region (1)
United States (12) · Canada (7) · United Kingdom (4) · Australia (3) · Hong Kong (3) · Ireland (3) · Switzerland (3) · Italy (2) · France (1) · India (1) · Israel (1) · New Zealand (1) · Norway (1) · Singapore (1) · Slovenia (1)
Barbro K Linderholm, MD, PhD (1) · Carlos E. Vargas, MD (1) · Charles B Simone (1) · Erin F Gillespie (1) · Fiona McDonald, MD (1) · Jennifer Y Wo (1) · Karen E Hoffman (1) · Laura Dawson (1) · Mariya Rozenblit (1) · Megan E Daly (1) · Neha Vapiwala (1) · Robert Timmerman, MD (1) · Rodney J Ellis (1) · Tyler Seibert (1) · Vincent Khoo, MD (1)
PMID 32736936, PMID 34903471, PMID 36223780, PMID 38421243, PMID 39615497, PMID 39699905, PMID 41063518, PMID 41732215, PMID 41825136, PMID 42593775, PMID 42702214
U10CA180868 (4), U10CA180888 (2), U10CA021661 (1), U10CA180820 (1), UG1CA189867 (1)