3 completed, 3 terminated. 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Terminated 3 |
Follow RRx-001: new trials by email Literature Review of RRx-001 trials Research Report on RRx-001
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors RRx-001, Temozolomide, Irinotecan - Brain Tumor, Recurrent, Brain Tumor, Pediatric | Phase 1 | Terminated | EpicentRx, Inc. | 2 | 2023-01-26 | 2024-10-31 |
| RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) RRx-001, Irinotecan - Malignant Solid Tumor, Metastatic Cancer | Phase 1 | Terminated | EpicentRx, Inc. | 28 | 2016-08-30 | 2022-05-17 |
| A Phase I, Open-Label, Multiple Ascending Dose Study of RRx-001 and Nivolumab RRx-001, Nivolumab - Malignant Solid Tumor, Lymphoma | Phase 1 | Completed | EpicentRx, Inc. | 12 | 2015-07-21 | 2019-11-18 |
| Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases RRx-001 + WBRT - Brain Metastases | Phase 1 | Completed | EpicentRx, Inc. | 29 | 2015-02-06 | 2021-11-03 |
| A Phase 1 Pilot Study of the Subcutaneous (s.c.) Route to Facilitate the Administration of RRx-001 RRx-001 - Malignant Solid Tumor, Lymphomas | Phase 1 | Terminated | EpicentRx, Inc. | 2 | 2014-04-01 | 2016-01-21 |
| Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects RRx-001 - Malignant Solid Tumor, Lymphomas | Phase 1 | Completed | EpicentRx, Inc. | 26 | 2011-09-01 | 2024-11-01 |
Lymphoma (3) · Brain Neoplasms (2) · Neoplasms (2) · Central Nervous System Neoplasms (1) · Neoplasm Metastasis (1) · Spinal Cord Neoplasms (1)
EpicentRx, Inc. (6)
United States (6)
Bryan Oronsky, MD (3) · Jeffrey Infante, MD (2) · Michelle Kim, MD (1) · Stephanie Fetzko, MD (1) · Tony Reid, MD (1)