6 completed, 1 active not recruiting, 1 not yet recruiting, 1 recruiting. 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Qsymia: new trials by email Literature Review of Qsymia trials Research Report on Qsymia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma Phentermine/Topiramate ER, Health Behavior and Lifestyle Counseling - Acute Lymphoblastic Leukemia in Remission, Hodgkin Lymphoma in Remission | Phase 2 | Not yet recruiting | St. Jude Children's Research Hospital | 100 | 2026-10-01 | 2026-09-23 |
| Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity Phentermine / Topiramate Extended Release Oral Capsule [Qsymia], Placebo - Hypothalamic Obesity, Hypothalamic Tumor | Phase 2 | Active not recruiting | Seattle Children's Hospital | 24 | 2025-03-01 | 2026-10-16 |
| Phentermine/Topiramate as Preventive Pharmacotherapy for Obesity Qsymia and lifestyle management therapy, Placebo and lifestyle management therapy - Obesity, Adolescent | Phase 2 | Withdrawn | University of Minnesota | 2023-10-17 | 2023-10-26 | |
| Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity Phentermine-Topiramate, Meal Replacement Therapy, Placebo - Obesity | Phase 2 | Completed | University of Minnesota | 100 | 2021-08-04 | 2026-05-26 |
| Phentermine/Topiramate for Uric Acid Stones Phentermine / Topiramate Oral Product, Citrate Salts, Allopurinol, Diet - Obesity, Uric Acid Stones | Phase 2 | Completed | University of Florida | 19 | 2021-03-31 | 2026-06-15 |
| Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients Phentermine-Topiramate, Placebo - Colitis, Ulcerative, Obesity | Phase 2 | Recruiting | University of California, San Diego | 40 | 2020-12-18 | 2023-05-16 |
| Phentermine/Topiramate Extended Release in Binge Eating Disorder (BED) PHEN/TPM ER (Qsymia®) - Binge Eating Disorder | Phase 2 | Completed | Lindner Center of HOPE | 10 | 2015-09-01 | 2016-09-20 |
| Qsymia as an Adjunct to Surgical Therapy in the Superobese Phentermine/topiramate, low calorie diet - Obesity, Metabolic Surgery | Phase 2 | Completed | Wake Forest University Health Sciences | 25 | 2014-12-01 | 2019-09-04 |
| Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate Propranolol, Pindolol, Dantrolene - Healthy Volunteers | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 47 | 2014-02-07 | 2024-10-16 |
| A VI-0521 Study to Evaluate the Long-term Safety and Efficacy in Type 2 Diabetic Adults Phentermine/Topiramate, Placebo - Diabetes | Phase 2 | Completed | VIVUS LLC | 130 | 2008-01-01 | 2012-09-10 |
Obesity (4) · Binge-Eating Disorder (1) · Colitis, Ulcerative (1) · Craniopharyngioma (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Glucose Intolerance (1) · Glucose Metabolism Disorders (1) · Hypothalamic Neoplasms (1) · Metabolic Diseases (1) · Pediatric Obesity (1) · Sexual Infantilism (1) · Weight Loss (1)
University of Minnesota (2) · Lindner Center of HOPE (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Seattle Children's Hospital (1) · St. Jude Children's Research Hospital (1) · University of California, San Diego (1) · University of Florida (1) · VIVUS LLC (1) · Wake Forest University Health Sciences (1)
United States (10)
Aaron Kelly, PhD (1) · Anna Guerdjikova, PhD,LISW (1) · Barbara Troupin, MD, MBA (1) · Benjamin Canales, MD (1) · Christian L Roth, MD (1) · Jamy D Ard, MD (1) · Kong Y Chen, Ph.D. (1) · Shana E McCormack, MD (1) · Stephanie Dixon, MD, MPH (1)
PMID 25249652, PMID 29980535, PMID 30013815
R21DK122317 (1)