6 unknown, 4 completed, 1 terminated. 3 Phase 2, 3 Phase 3, 3 Phase 4, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 3 | Unknown 2, Terminated 1 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
Follow Prostaglandin E1: new trials by email Literature Review of Prostaglandin E1 trials Research Report on Prostaglandin E1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Dexamethasone for Inducing Labor in Women With Term Pregnancy and Pre-Labour Rupture of Membranes Dexamethasone, Prostaglandin E1, Normal Saline - Rupture of Membranes Prior to Onset of Labor, Induction of Labor | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-31 |
| Letrozole in Induction of Abortion of Anembryonic Pregnancy Letrozole tablets, Misoprostol Tabets, Placebo tablets - Anembryonic Pregnancy | Not applicable | Completed | Cairo University | 96 | 2022-04-03 | 2023-09-11 |
| To Study the Efficacy and Safety of Misoprostol by Sublingual Routes for Induction of Labour Misoprostol - Induction of Labour | Not applicable | Unknown | Ministry of Health, Bhutan | 500 | 2021-06-01 | 2021-05-17 |
| Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage misoprostol - Miscarriage, Misoprostol | Phase 2 | Completed | Islamabad Medical and Dental College | 120 | 2020-11-02 | 2022-05-24 |
| Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section Misoprostol, Placebo - Transient Tachypnea of the Newborn, Neonatal Respiratory Distress | Phase 3 | Unknown | Ain Shams University | 210 | 2020-09-01 | 2021-03-03 |
| Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns Prostaglandin E1 - Pyloric Stenosis;Acquired, Congenital Heart Disease | Unknown | Hacettepe University | 20 | 2019-05-06 | 2020-08-03 | |
| Labor Induction and Maternal BMI, Comparison of Different Pre-induction Cervical Ripening Methods Cook double balloon catheter, PGE1 tablet - Obesity, Labor Complications | Phase 2 / Phase 3 | Unknown | Hillel Yaffe Medical Center | 624 | 2014-10-01 | 2014-08-22 |
| Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy Alprostadil ﹠control - Kidney Diseases, Diabetes Mellitus | Phase 4 | Unknown | Shanghai 10th People's Hospital | 150 | 2012-11-01 | 2012-11-07 |
| The Use of Prostaglandin E1 in Head and Neck Microsurgery Prostaglandin E1, Saline - Microsurgery, Head and Neck | Phase 4 | Unknown | National Taiwan University Hospital | 242 | 2008-07-01 | 2009-10-27 |
| ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted Prostatectomy for Prostate Cancer sildenafil citrate, alprostadil, robotic-assisted laparoscopic surgery - Prostate Cancer, Male Erectile Disorder | Phase 3 | Terminated | City of Hope Medical Center | 110 | 2006-01-01 | 2019-01-02 |
| Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer Alprostadil (E1), Papaverine, Phentolamine mesylate - Prostate Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 111 | 2001-08-01 | 2012-07-30 |
Prostatic Neoplasms (2) · Abortion, Spontaneous (1) · Acute Kidney Injury (1) · Diabetes Mellitus (1) · Erectile Dysfunction (1) · Fetal Membranes, Premature Rupture (1) · Heart Defects, Congenital (1) · Infertility (1) · Kidney Diseases (1) · Kidney Failure, Chronic (1) · Obesity (1) · Obstetric Labor Complications (1) · Postoperative Complications (1) · Pulmonary Atelectasis (1) · Renal Insufficiency (1)
Ain Shams University (1) · Cairo University (1) · City of Hope Medical Center (1) · Hacettepe University (1) · Hillel Yaffe Medical Center (1) · Islamabad Medical and Dental College (1) · M.D. Anderson Cancer Center (1) · Ministry of Health, Bhutan (1) · National Taiwan University Hospital (1) · Nishtar Medical University (1) · Shanghai 10th People's Hospital (1)
Egypt (2) · Pakistan (2) · United States (2) · Bhutan (1) · China (1) · Israel (1) · Taiwan (1) · Turkey (Türkiye) (1)
Asnat Walfisch, MD (1) · Christopher G. Wood, MD (1) · Hasan T Celik, Ass Prof. (1) · Laura Crocitto (1) · Marwa M Abdalla, MD (1) · Saja Murra Anabosy, MD (1) · Samar A. Kandeel (1) · Syeda A Professor, FCPS (1) · Ya-Wei Xu, MD, FACC (1) · Yeshey Dorjey (1) · Yueh-Bih Tang, MD, PhD (1)
PMID 10607766, PMID 18783876, PMID 36856877, PMID 36996264
P30CA016672 (1), P50CA090270 (1)