14 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 5 Phase 2, 3 Phase 1, 3 Phase 3, 3 Phase 4, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 3 | Active not recruiting 1, Completed 1, Recruiting 1 |
| Not applicable | 2 | Completed 2 |
Follow Pneumococcal conjugate vaccine: new trials by email Literature Review of Pneumococcal conjugate vaccine trials Research Report on Pneumococcal conjugate vaccine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Opportunistic Pneumococcal Immunisation Trial in MALnutrition Pneumococcal conjugate vaccine, Typhoid conjugate vaccine - Severe Acute Malnutrition in Childhood, Pneumococcal Disease | Phase 4 | Recruiting | Nick Fancourt | 214 | 2026-01-16 | 2026-10-08 |
| Evaluating the Effectiveness of a Pneumococcal Immunisation Campaign in a Camp for Internally Displaced People Pneumococcal conjugate vaccine - Pneumococcal Infections | Phase 4 | Active not recruiting | London School of Hygiene and Tropical Medicine | 2882 | 2022-11-27 | 2025-06-04 |
| Safety and Immunogenicity of a Pneumococcal Conjugate Vaccine Candidate in Healthy Adults (19-49 Years) Pneumococcal Conjugate Vaccine, Prevnar 13® - Pneumococcal Immunization | Phase 1 | Completed | Sanofi Pasteur, a Sanofi Company | 175 | 2018-12-03 | 2024-11-20 |
| Study to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine Given With Prevnar 13 in Healthy Infants Multivalent, Prevnar 13 - Pneumococcal Infections | Phase 2 | Terminated | Pfizer | 565 | 2018-06-01 | 2021-11-30 |
| Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine in Healthy Infants Multivalent, 13vPnC - Pneumococcal Infections | Phase 2 | Completed | Pfizer | 460 | 2018-04-16 | 2021-03-02 |
| Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine (Bio Farma) in Adults and Children (Phase I) Vi-DT (Bio Farma), Vi polysaccharide vaccine, Influenzae vaccine - Safety Issues | Phase 1 | Completed | PT Bio Farma | 100 | 2017-04-18 | 2018-03-06 |
| A Phase I Clinical Trial of a 13-valent Pneumococcal Conjugate Vaccine and 14-valent Pneumococcal Conjugate Vaccine in Adults Pneumococcal conjugate vaccine - Pneumococcal Infections | Phase 1 | Completed | LG Life Sciences | 63 | 2016-09-01 | 2017-06-26 |
| Vaccination Against Pneumococcal in Naïve Abatacept Rheumatoid Arthritis Patients pneumococcal polysaccharide vaccine, pneumococcal conjugate vaccine, Abatacept - Rheumatoid Arthritis | Not applicable | Completed | University Hospital, Montpellier | 80 | 2016-03-03 | 2022-01-03 |
| Exploration of Immune Response to Early PCV13 Vaccination in Conjunction With Autologous Transplant PCV 13 - Multiple Myeloma | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 8 | 2013-02-01 | 2017-02-02 |
| Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Children, Older Infants and Infants Vi-CRM197 vaccine, Pneumococcal conjugate vaccine, Vi Polysaccharide (PS) vaccine - Typhoid Fever | Phase 2 | Completed | Novartis | 120 | 2011-10-01 | 2014-04-10 |
| Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adults, Children, Older Infants and Infants Vi-CRM197 vaccine, Vi Polysaccharide (PS) vaccine, Pneumococcal conjugate vaccine - Typhoid Fever | Phase 2 | Completed | Novartis | 200 | 2011-03-01 | 2014-05-01 |
| Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants MenACWY-CRM197, DTaP (Diptheria, Tetanus, Pertussis) Vaccine, Hib (Haemophilus influenza b) Vaccine - Meningitis, Meningococcal Infection | Phase 3 | Completed | Novartis | 7744 | 2008-12-01 | 2013-07-09 |
| Pneumococcal Vaccine Booster Study in Healthy Children 12-18 Mths Old Previously Primed With the Same Vaccines Synflorix, Tritanrix-HepB, Hiberix - Infections, Streptococcal | Phase 3 | Completed | GlaxoSmithKline | 756 | 2007-10-22 | 2019-01-14 |
| Safety and Local Tolerability of Prevenar in Indian Children pneumococcal conjugate vaccine - Pneumococcal Infections | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 1000 | 2006-07-01 | 2007-12-28 | |
| Targeting of Immune Response After Pneumococcal Vaccination Pneumococcal polysaccharide vaccine, pneumococcal conjugate vaccine - Pneumococcal Pneumonia | Phase 4 | Completed | Helsinki University Central Hospital | 42 | 2005-01-01 | 2011-07-26 |
| Evaluation of the Immunogenicity and Reactogenicity of a Pneumococcal Conjugate Vaccine in Healthy Adults pneumococcal conjugate vaccine - Streptococcus Pneumoniae | Phase 2 | Completed | Public Health England | 611 | 2004-01-01 | 2012-03-28 |
| Pneumococcal Conjugate Vaccination in HIV in Comparison to Polysaccharide Vaccine Boosting pneumococcal conjugate vaccine, pneumococcal polysaccharide vaccine - HIV Infections, Streptococcus Pneumoniae | Phase 3 | Completed | Henry M. Jackson Foundation for the Advancement of Military Medicine | 275 | 2002-12-01 | 2025-06-08 |
Pneumococcal Infections (7) · Pneumonia (2) · Typhoid Fever (2) · Arthritis, Rheumatoid (1) · HIV Infections (1) · Meningitis (1) · Meningococcal Infections (1) · Multiple Myeloma (1) · Pneumonia, Pneumococcal (1) · Streptococcal Infections (1)
Novartis (3) · Pfizer (2) · GlaxoSmithKline (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Helsinki University Central Hospital (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · LG Life Sciences (1) · London School of Hygiene and Tropical Medicine (1) · Nick Fancourt (1) · PT Bio Farma (1) · Public Health England (1) · Sanofi Pasteur, a Sanofi Company (1) · University Hospital, Montpellier (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
United States (6) · Philippines (2) · China (1) · Costa Rica (1) · Finland (1) · France (1) · Guatemala (1) · India (1) · Indonesia (1) · Monaco (1) · Pakistan (1) · Panama (1) · Peru (1) · Poland (1) · Somalia (1)
Anu Kantele, MD PhD (1) · Bernie Endyarni, MD (1) · Brian Agan, MD (1) · Elizabeth Miller, MBBS FRCPath (1) · Frederick L Locke, MD (1) · Jacques Morel, MD PhD (1) · Maria Rosario Z Capeding, MD (1) · Myoung-don Oh, M.D. (1)
PMID 24290843, PMID 19814624, PMID 20795819, PMID 20887830, PMID 34525007, PMID 37927075, PMID 39633426, PMID 41265006