9 completed, 2 unknown. 11 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 9, Unknown 2 |
| Phase 2 | 4 | Completed 4 |
Follow Placebo cream: new trials by email Literature Review of Placebo cream trials Research Report on Placebo cream
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar AK3280 Cream, Placebo cream - Hypertrophic Scar | Phase 1 / Phase 2 | Completed | Shanghai Ark Biopharmaceutical Co., Ltd. | 30 | 2022-07-08 | 2026-06-22 |
| Phase I Study of GN-037 Cream for Psoriasis GN037, Placebo - Psoriasis | Phase 1 | Completed | TC Erciyes University | 24 | 2022-03-28 | 2023-06-13 |
| Effectivity and Safety of Combination of Spent Grain Wax, Argan Oil, Shea Butter and Saccharide Isomerate Combination cream, Placebo cream - Acne Vulgaris | Phase 1 | Unknown | Dr.dr.Irma Bernadette, SpKK (K) | 20 | 2021-12-20 | 2022-01-11 |
| A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome SXR1096 cream, Placebo cream - Netherton Syndrome | Phase 1 / Phase 2 | Completed | Sixera Pharma | 9 | 2021-12-07 | 2025-12-16 |
| Topical Sm29 in Combination With Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis. Sm29 Protein, Schistosoma Mansoni, Pentavalent antimony (Sbv) - Cutaneous Leishmaniasis, American | Phase 1 / Phase 2 | Completed | Hospital Universitário Professor Edgard Santos | 20 | 2019-01-17 | 2023-08-21 |
| Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm Clarithromycin (Not used as of 4/2020), Placebo (Not used as of 4/2020), Transdermal flumazenil (Added 4/2020) - Parkinson Disease | Phase 1 / Phase 2 | Completed | Nicolaas Bohnen, MD, PhD | 34 | 2018-01-29 | 2023-01-10 |
| Trial of Mannitol Cream for Pain Relief After a Long Run Mannitol cream, Placebo Cream - Pain | Phase 1 | Completed | University of British Columbia | 170 | 2013-05-01 | 2013-10-11 |
| A Physiological Study on Downregulation of EGF-receptors in the Skin by Topical Exposition With EGF Human recombinant epidermal growth factor, Placebo cream - Plaque Psoriasis | Phase 1 | Unknown | Ennar Pharmaceuticals AF | 24 | 2012-04-01 | 2012-08-03 |
| Safety, Tolerability and Pharmacokinetics of MK-0873 Following Patch Application in Healthy Participants and Psoriasis Participants (MK-0873-020) MK-0873 Patch, MK-0873 Cream, Placebo Patch - Plaque Psoriasis | Phase 1 | Completed | Merck Sharp & Dohme LLC | 42 | 2010-05-01 | 2019-02-08 |
| Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon placebo cream, Glyceryl Trinitrate - Raynaud's Phenomenon | Phase 1 | Completed | Procris Pharmaceuticals | 10 | 2008-06-01 | 2008-12-30 |
| The Role of Arnica on Muscle Pain Following Eccentric Exercise Arnica Montana, placebo cream - Muscles, Exercise | Phase 1 | Completed | The University of Texas Health Science Center, Houston | 55 | 2007-08-01 | 2009-01-07 |
Motor Activity (2) · Acne Vulgaris (1) · Cicatrix, Hypertrophic (1) · Leishmaniasis, Cutaneous (1) · Leishmaniasis, Mucocutaneous (1) · Myalgia (1) · Netherton Syndrome (1) · Pain (1) · Parkinson Disease (1) · Psoriasis (1) · Raynaud Disease (1)
Dr.dr.Irma Bernadette, SpKK (K) (1) · Ennar Pharmaceuticals AF (1) · Hospital Universitário Professor Edgard Santos (1) · Merck Sharp & Dohme LLC (1) · Nicolaas Bohnen, MD, PhD (1) · Procris Pharmaceuticals (1) · Shanghai Ark Biopharmaceutical Co., Ltd. (1) · Sixera Pharma (1) · TC Erciyes University (1) · The University of Texas Health Science Center, Houston (1) · University of British Columbia (1)
United States (3) · Austria (1) · Brazil (1) · Canada (1) · China (1) · France (1) · Germany (1) · Indonesia (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1)
David W Bauer, MD (1) · Helene Bertrand, MD, CCFP (1) · Irma BS Sitohang, MD (1) · Jihong Liu (1) · Maarten de Chateau, MD PhD (1) · Nicolaas I Bohnen, MD, PhD (1) · Yan Wu (1)
PMID 22236612, PMID 37300792, PMID 39147194
R01NS099535 (1)