6 completed, 2 recruiting, 2 unknown. 6 Not applicable, 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Unknown 2, Recruiting 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 2 |
Follow piperine: new trials by email Literature Review of piperine trials Research Report on piperine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Curcumin-Piperine Supplementation in STEMI - SPICE STEMI Trial Curcumin plus Piperine, Placebo capsules - ST Elevation Myocardial Infarction (STEMI), Malondialdehyde | Not applicable | Completed | Universitas Diponegoro | 50 | 2025-02-05 | 2025-09-02 |
| Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Clonal Cytopenia of Undetermined Significance, Essential Thrombocythemia | Phase 2 | Recruiting | University of Southern California | 30 | 2024-03-01 | 2026-03-27 |
| Effects of 6-month of Treatment With TRPV1 and TRPA1 Agonists in Older Patients With OD Capsaicin, Piperine, Placebo - Oropharyngeal Dysphagia, Swallowing Disorder | Not applicable | Unknown | Hospital de Mataró | 150 | 2023-09-01 | 2023-07-24 |
| Curcumin Supplementation in Cervical Cancer Curcumin, Curcumin + Piperine - Locally Advanced Cervical Cancer | Not applicable | Recruiting | National Institute of Cancerología | 30 | 2023-04-19 | 2025-05-25 |
| Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer Curcumin plus Piperine - Prostate Cancer, Multiple Myeloma | Phase 2 | Completed | University of Rochester | 30 | 2021-12-14 | 2026-05-12 |
| Treatment of Acute Post-stroke Oropharyngeal Dysphagia With Paired Stimulation Piperine 150μM + tDCS 2mA, Piperine 1mM + tDCS 2mA, Capsaicin 10μM + tDCS 2mA - Stroke, Stroke, Acute | Not applicable | Unknown | Hospital de Mataró | 60 | 2021-07-01 | 2023-02-21 |
| Effects of Curcumin in Patients in Chronic Kidney Disease Active Comparator: Supplement A, Placebo Comparator: Supplement B - Chronic Kidney Diseases | Not applicable | Completed | Denise Mafra | 30 | 2018-02-22 | 2023-12-15 |
| Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer Curcumin, Laboratory Biomarker Analysis, Piperine Extract (Standardized) - Bladder Spasm, Malignant Neoplasm | Phase 1 | Completed | Mayo Clinic | 9 | 2016-03-01 | 2025-04-22 |
| Effect Of Piperine In Patients With Oropharyngeal Dysphagia Piperine - Deglutition Disorders | Phase 1 / Phase 2 | Completed | Hospital de Mataró | 40 | 2011-06-01 | 2015-03-03 |
| Resveratrol With or Without Piperine to Enhance Plasma Levels of Resveratrol Resveratrol, Resveratrol 2.5 grams x 1 dose and Piperine 5 mg x 1 dose, Resveratrol 2.5 grams x 1 dose and Piperine 25 mg x 1 dose - Focus of the Study: Normal Volunteers | Not applicable | Completed | University of Wisconsin, Madison | 24 | 2011-03-01 | 2019-12-13 |
Deglutition Disorders (3) · Inflammation (1) · Monoclonal Gammopathy of Undetermined Significance (1) · Multiple Myeloma (1) · Myelodysplastic Syndromes (1) · Neoplasms (1) · Pain (1) · Polycythemia Vera (1) · Primary Myelofibrosis (1) · Prostatic Neoplasms (1) · Renal Insufficiency, Chronic (1) · ST Elevation Myocardial Infarction (1) · Smoldering Multiple Myeloma (1) · Stroke (1) · Thrombocythemia, Essential (1)
Hospital de Mataró (3) · Denise Mafra (1) · Mayo Clinic (1) · National Institute of Cancerología (1) · Universitas Diponegoro (1) · University of Rochester (1) · University of Southern California (1) · University of Wisconsin, Madison (1)
United States (4) · Spain (3) · Brazil (1) · Indonesia (1) · Mexico (1)
Aminah Jatoi, M.D. (1) · Brea Lipe (1) · Casey L O'Connell, MD (1) · Denisse Castro, RDN, PhD (1) · Fahri Husaini Alkaf, M.D. (1) · Howard H Bailey, MD (1)
PMID 10051376, PMID 11376301, PMID 1291482, PMID 16371925, PMID 16545122, PMID 17569205, PMID 21441148, PMID 22481014, PMID 23514412, PMID 24191240, PMID 24326980, PMID 25068024, PMID 25618800, PMID 25639761, PMID 26942997, PMID 27398981, PMID 28819546, PMID 29445400, PMID 30496103, PMID 30956054, PMID 32204978, PMID 33799960, PMID 35460440, PMID 36142680, PMID 36712505, PMID 37760934, PMID 38082237, PMID 38092508, PMID 38792942, PMID 40171210, PMID 8827060, PMID 9291902, PMID 9619120
P30CA014089 (1), R21CA149560 (1), UG1CA189823 (1)