5 completed, 3 recruiting, 2 active not recruiting, 2 withdrawn. 5 Not applicable, 4 Phase 2, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Active not recruiting 2, Completed 2, Recruiting 1 |
| Phase 2 | 4 | Completed 1, Suspended 1, Unknown 1, Withdrawn 1 |
| Early Phase 1 | 1 | Withdrawn 1 |
| Phase 1 | 1 | Suspended 1 |
Follow pimonidazole: new trials by email Literature Review of pimonidazole trials Research Report on pimonidazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Hypoxia in Primary Melanoma Pimonidazole - Melanoma | Recruiting | Yana Najjar | 50 | 2025-04-09 | 2026-06-10 | |
| A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers fMRI, Oral Pimonidazole - Squamous Cell Carcinoma of Head and Neck | Not applicable | Recruiting | University Health Network, Toronto | 60 | 2024-01-29 | 2026-08-06 |
| Total Tumor Mapping (TTM) for Resectable Pancreatic Cancer Pimonidazole, Surgical Resection - Pancreatic Cancer, Resectable Pancreatic Cancer | Early Phase 1 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2021-04-01 | 2021-02-08 | |
| Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma Pimonidazole - Melanoma | Recruiting | Yana Najjar | 20 | 2021-02-24 | 2026-06-11 | |
| FAZA PET/MRI Sarcoma 18F-FAZA, Pimonidazole - Sarcoma | Not applicable | Active not recruiting | University Health Network, Toronto | 70 | 2018-03-27 | 2026-08-10 |
| Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer (18)F-Fluoroazomycin arabinoside, Pimonidazole - Tongue Cancer | Phase 1 / Phase 2 | Suspended | Sunnybrook Health Sciences Centre | 10 | 2018-01-25 | 2024-08-12 |
| Pimo Study: Extracellular Vesicle-based Liquid Biopsy to Detect Hypoxia in Tumours Hypoxia marker - Cancer | Not applicable | Completed | Institute of Cancer Research, United Kingdom | 21 | 2017-11-10 | 2019-12-23 |
| Hypoxia Analysis in Head and/or Neck Cancer Pimonidazole - Head and Neck Cancer | Phase 2 | Unknown | Marius Gustav Bredell | 10 | 2015-04-01 | 2016-06-17 |
| Biomarker Correlates of Hypoxia in Metastatic Melanoma Pimonidazole hydrochloride (Hypoxyprobe™-1), Optional 18F-FMISO PET scan (18F-fluoromisonidazole), Surgical Resection of Melanoma Metastases - Melanoma, Skin Cancer | Phase 2 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2014-10-01 | 2016-05-09 | |
| Prostate Hypoxia - TIC Pimonidazole - Prostate Cancer | Not applicable | Active not recruiting | University Health Network, Toronto | 39 | 2014-09-01 | 2026-06-23 |
| Novel Window of Opportunity Trial to Evaluate the Impact of Statins to Oppose Prostate Cancer Fluvastatin, Pimonidazole - Prostate Cancer | Phase 2 | Completed | University Health Network, Toronto | 33 | 2014-02-01 | 2017-10-26 |
| RHYTHM-I: Investigating Hypoxia in Rectal Tumours Pimonidazole, F-MISO PET, pCT - Hypoxia in Rectal Cancer | Not applicable | Completed | University of Oxford | 14 | 2013-10-01 | 2017-03-13 |
| Role of Nox2 in CNI-induced Renal Fibrosis Hypoxyprobe-1 - Kidney Disease | Completed | University of Wisconsin, Madison | 8 | 2012-11-30 | 2019-10-14 | |
| Study of Intratumoral Hypoxia Using Pre-operative Administration of Pimonidazole Pimonidazole hydrochloride - Pancreatic Cancer | Completed | University Health Network, Toronto | 200 | 2010-10-01 | 2026-07-10 |
Hypoxia (4) · Melanoma (3) · Pancreatic Neoplasms (2) · Prostatic Neoplasms (2) · Head and Neck Neoplasms (1) · Immune System Diseases (1) · Kidney Diseases (1) · Neoplasms (1) · Rectal Neoplasms (1) · Sarcoma (1) · Skin Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Tongue Neoplasms (1)
University Health Network, Toronto (5) · H. Lee Moffitt Cancer Center and Research Institute (2) · Yana Najjar (2) · Institute of Cancer Research, United Kingdom (1) · Marius Gustav Bredell (1) · Sunnybrook Health Sciences Centre (1) · University of Oxford (1) · University of Wisconsin, Madison (1)
Canada (6) · United States (4) · United Kingdom (2) · Switzerland (1)
Alejandro Berlin, MD. (1) · Arjang Djamali, MD,MS,FASN (1) · Ian Poon, MD, FRCPC (1) · Jonathan Zager, M.D. (1) · Marius Bredell (1) · Navita Somaiah (1) · Neesha Dhani, MD (1) · Sarah Hoffe, MD (1) · Tim Maughan (1) · Yana M Najjar, MD (1) · Yana Najjar, MD (1)
R01DK092454 (1)