4 completed, 4 not yet recruiting, 2 recruiting. 3 Phase 2, 3 Phase 4, 2 Phase 1, 2 Phase 3, 1 Not applicable.
Follow Normal (0.9%) saline: new trials by email Literature Review of Normal (0.9%) saline trials Research Report on Normal (0.9%) saline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Controlled Trial Evaluating the Efficacy of Soaking Endotracheal Tube in Dexamethasone Solution for Prevention of Postoperative Sore Throat After Laparoscopic Cholecystectomy Steroid Drug, Normal (0.9%) saline - Post Operative Sore Throat | Phase 2 | Not yet recruiting | KRL Hospital, Islamabad | 64 | 2026-11-01 | 2026-09-16 |
| Hypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar. Normal (0.9%) saline, Hypertonic 3% saline - Symptomatic Irreversible Pulpitis (SIP) | Phase 4 | Not yet recruiting | Cairo University | 40 | 2026-08-01 | 2026-07-14 |
| Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological Surgery Esmolol hydrochloride, Dexmedetomidine, Normal (0.9%) saline - Pain, Acute Post-Operative, Dexmedetomidine | Not applicable | Recruiting | Vasiliki Samartzi | 90 | 2026-07-15 | 2026-09-29 |
| Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUH tranexamic acid (1 g diluted in 100 mL of 0.9% saline, Normal (0.9%) saline - Post Partum Haemorrhage | Phase 3 | Not yet recruiting | Sultan Qaboos University | 88 | 2026-05-01 | 2026-04-01 |
| Effect of Acetylcysteine Inhalation on Incidence and Time to Develop Ventilator Associated Pneumonia in Critically Ill Mechanically Ventilated Patients Acetyl cysteine, Normal (0.9%) saline - Ventilation Acquired Pneumonia | Phase 4 | Recruiting | Cairo University | 80 | 2026-03-01 | 2026-07-10 |
| Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction exosomes derived from human umbilical cord mesenchymal stem cells, Normal (0.9%) saline - Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus | Phase 2 | Not yet recruiting | Labbafinejad Medical Center | 70 | 2026-01-01 | 2026-01-06 |
| Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy Bupivacain (Postoperative), Normal (0.9%) saline - Laparoscopic Cholecystectomy, Post Operative Analgesia | Phase 4 | Completed | Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh | 60 | 2024-07-11 | 2025-08-01 |
| Use of Hydrogen Sulphide Donor (N-acetyl Cysteine) in Cases With Acute Ischemic Stroke N Acetyl cysteine 600mg, Normal (0.9%) saline - Ischemic Cerebral Infarction | Phase 3 | Completed | Helwan University | 121 | 2021-06-01 | 2026-08-06 |
| The Effect of Acute Lysine Administration on α-aminoadipic Acid L-Lysine, Normal (0.9%) Saline - Healthy, Pre-diabetic | Phase 1 | Completed | Vanderbilt University | 13 | 2016-05-01 | 2017-02-07 |
| Yoga and Bolus Lukewarm Saline as Rapid Colonoscopy Preparation Normal (0.9%) saline, HalfLytely - Colonic Neoplasms | Phase 1 / Phase 2 | Completed | Arya, Vijaypal, M.D., P.C. | 133 | 2008-05-01 | 2015-03-04 |
Pain, Postoperative (2) · Agnosia (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Erectile Dysfunction (1) · Gallstones (1) · Glucose Intolerance (1) · Ischemic Stroke (1) · Myocardial Ischemia (1) · Nociceptive Pain (1) · Postpartum Hemorrhage (1)
Cairo University (2) · Arya, Vijaypal, M.D., P.C. (1) · Helwan University (1) · KRL Hospital, Islamabad (1) · Labbafinejad Medical Center (1) · Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh (1) · Sultan Qaboos University (1) · Vanderbilt University (1) · Vasiliki Samartzi (1)
Egypt (2) · Pakistan (2) · Greece (1) · Iran (1) · United States (1)
Dr Ammar Ali Shah, MBBS DA FCPS MHPE Fellowship (1) · Jane F Ferguson, PhD (1) · Noman Yousaf, MBBS (1) · Vijaypal Arya, MD (1)