3 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 3, Not yet recruiting 1, Recruiting 1, Terminated 1, Unknown 1 |
Follow Nitrofurantoin: new trials by email Literature Review of Nitrofurantoin trials Research Report on Nitrofurantoin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries Oral nitrofurantoin monohydrate/macrocrystals, Placebo - Preterm Birth, Small for Gestational Age (SGA) | Phase 3 | Recruiting | NICHD Global Network for Women's and Children's Health | 1134 | 2025-12-08 | 2026-01-22 |
| An Open Clinical Trial of the Safety and Efficacy of the Drug Fluorothiazinone, 300 Mg Tablets with the Participation of Adult Patients with Chronic Bacterial Cystitis" Fluorothiazinone, tablets 300 mg, Nitrofurantoin 100 MG - P. Aeruginosa, Baumannii | Phase 3 | Not yet recruiting | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 280 | 2025-02-17 | 2025-02-07 |
| A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis) Gepotidacin, Nitrofurantoin, Placebo - Urinary Tract Infections | Phase 3 | Completed | GlaxoSmithKline | 380 | 2023-01-11 | 2025-03-17 |
| EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care Fosfomycin, Nitrofurantoin - Urinary Tract Infections | Phase 3 | Terminated | MJM Bonten | 13 | 2021-09-06 | 2022-03-15 |
| Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) Gepotidacin, Placebo matching nitrofurantoin, Nitrofurantoin - Urinary Tract Infections | Phase 3 | Completed | GlaxoSmithKline | 1606 | 2020-04-23 | 2023-07-18 |
| A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) Gepotidacin, Placebo matching nitrofurantoin, Nitrofurantoin - Urinary Tract Infections | Phase 3 | Completed | GlaxoSmithKline | 1531 | 2019-10-17 | 2023-06-22 |
| Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract nitrofurantoin, No prophylaxis, Amoxicillin-Potassium Clavulanate Combination - Vesicoureteral Reflux, Renal Hypodysplasia, Nonsyndromic, 1 | Phase 3 | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 292 | 2013-12-01 | 2023-09-28 |
Urinary Tract Infections (4) · Bacteriuria (1) · Premature Birth (1) · Renal Hypodysplasia, Nonsyndromic, 1 (1) · Renal Insufficiency, Chronic (1) · Stillbirth (1) · Vesico-Ureteral Reflux (1)
GlaxoSmithKline (3) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation (1) · MJM Bonten (1) · NICHD Global Network for Women's and Children's Health (1)
India (3) · Bulgaria (2) · United States (2) · Australia (1) · Bangladesh (1) · Czechia (1) · Democratic Republic of the Congo (1) · Germany (1) · Greece (1) · Guatemala (1) · Hungary (1) · Italy (1) · Japan (1) · Mexico (1) · Netherlands (1)
Aleksandra M Zurowska, Professor (1) · Enrico Verrina, MD (1) · Esra Baskin, Professor (1) · Fatos Yalcinkaya, Professor (1) · Franz Schaefer, Professor (1) · Giovanni Montini, MD (1) · Lutz T. Weber, Professor (1) · Marc Bonten, Prof. (1) · Otto Mehls, Professor (1) · Piotr Czarniak, MD (1) · William Morello, MD (1)
PMID 34978887, PMID 36255258, PMID 36271314, PMID 38342126, PMID 40372095, PMID 40924001, PMID 40924012, PMID 41399629, PMID 41495938, PMID 42682990, PMID 37702442
2018 (1)