8 completed, 1 terminated. 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 8, Terminated 1 |
Follow nepafenac: new trials by email Literature Review of nepafenac trials Research Report on nepafenac
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PGE2 Levels in Patient Treated With NSAIDs Placebo, Dicloftil, Nevanac - Ocular Inflammation | Phase 3 | Completed | University of Trieste | 104 | 2018-04-25 | 2018-07-24 |
| Clinical Endpoint Study of Nepafenac 0.3% Opthalmic Suspension Nepafenac 0.3% Oph Susp, Placebos, Nepafenac 0.3% Oph Susp (reference) - Cataract | Phase 3 | Completed | Actavis Inc. | 448 | 2018-03-28 | 2021-02-16 |
| NSAIDs and PGE2 Levels in Vitrectomy Patients Ketorolac 0.5% eyedrops, Indomethacin 0.5% eyedrops, Bromfenac 0.09% eyedrops - Vitreous Inflammation | Phase 3 | Completed | Università degli Studi di Brescia | 70 | 2014-03-01 | 2015-02-12 |
| Nepafenac Once Daily for Macular Edema - Study 1 Nepafenac Ophthalmic Suspension, 0.3%, Nepafenac vehicle, Prednisolone acetate - Non-Proliferative Diabetic Retinopathy, Cataract | Phase 3 | Completed | Alcon Research | 881 | 2013-06-01 | 2016-08-03 |
| Nepafenac Once Daily for Macular Edema - Study 2 Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate - Non-Proliferative Diabetic Retinopathy, Cataract | Phase 3 | Completed | Alcon Research | 819 | 2013-06-01 | 2016-08-02 |
| Confirmatory Study Nepafenac 0.3% Nepafenac Ophthalmic Suspension, 0.3%, Nepafenac Ophthalmic Suspension, 0.1%, Nepafenac Ophthalmic Suspension 0.3% Vehicle - Cataract | Phase 3 | Completed | Alcon Research | 2120 | 2010-06-01 | 2012-11-30 |
| Macular Edema Incidence/Severity Reduction With Nevanac Nepafenac ophthalmic suspension, 0.1% (NEVANAC®), Nepafenac ophthalmic suspension vehicle - Diabetic Retinopathy | Phase 3 | Terminated | Alcon Research | 175 | 2009-08-01 | 2012-10-23 |
| Efficacy Study of Triamcinolone Associated With Nepafenac for Treatment of Diabetic Macular Edema Triamcinolone + Nepafenac, triamcinolone intravitreal injection - Diabetic Macular Edema | Phase 3 | Completed | Federal University of São Paulo | 40 | 2007-07-01 | 2018-03-20 |
| Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo Nepafenac 1mg/ml eye drops, suspension, Ketorolac Trometamol 5 mg/ml eye drops, solution, Nepafenac vehicle eye drops - Cataracts | Phase 3 | Completed | Alcon Research | 227 | 2005-11-01 | 2016-11-18 |
Cataract (5) · Macular Edema (4) · Diabetes Mellitus, Type 1 (2) · Diabetes Mellitus, Type 2 (2) · Diabetic Retinopathy (1) · Epiretinal Membrane (1) · Retinal Perforations (1)
Alcon Research (5) · Actavis Inc. (1) · Federal University of São Paulo (1) · University of Trieste (1) · Università degli Studi di Brescia (1)
United States (3) · Brazil (1) · France (1) · Italy (1)
Dana Sager, MS (1) · Marco R Pastore, MD (1) · Rubens Belfort Jr, MD (1)
PMID 19668532, PMID 27388251, PMID 33595256
2005 (1)