10 completed, 8 recruiting, 2 not yet recruiting, 2 terminated. 10 Not applicable, 6 Phase 2, 4 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow mpMRI: new trials by email Literature Review of mpMRI trials Research Report on mpMRI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer ultiparametric Magnetic Resonance Imaging, Perflutren lipid microsphere, Transrectal Ultrasound - Prostate Carcinoma | Phase 3 | Not yet recruiting | Thomas Jefferson University | 300 | 2026-10-01 | 2026-08-25 |
| Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer Biopsy Procedure, Biospecimen Collection, High-Dose Rate Brachytherapy - Prostate Adenocarcinoma, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 45 | 2026-05-11 | 2026-05-22 |
| Early Prediction of Neoadjuvant Chemotherapy Response in Bladder Cancer Using Quantitative Multiparametric MRI Multiparametric Magnetic Resonance Imaging (mpMRI) - MIBC, mpMRI | Recruiting | Assiut University | 39 | 2025-08-29 | 2025-10-02 | |
| An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique Flotufolastat F-18 Gallium, Magnetic Resonance Imaging, Multiparametric Magnetic Resonance Imaging - Prostate Carcinoma | Phase 2 | Recruiting | Emory University | 90 | 2025-04-18 | 2026-07-14 |
| Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer hyperpolarized pyruvate +/-urea (13C/15N), Non-investigational External beam radiotherapy (EBRT), Radiotherapy (RT) - Prostate Cancer | Phase 2 | Recruiting | Robert Bok, MD, PhD | 161 | 2024-09-24 | 2026-01-07 |
| MRI and CT in Gastroesophageal Junction or Upper Gastric Adenocarcinoma mpMRI - Gastric Cancer, Gastroesophageal Junction Cancer | Active not recruiting | The First Affiliated Hospital with Nanjing Medical University | 100 | 2024-08-21 | 2024-10-15 | |
| Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial Apalutamide, Biospecimen Collection, Computed Tomography - Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 95 | 2024-03-28 | 2026-07-17 |
| Prostate Resection After Microwave Ablation (PRAMA) Biospecimen Collection, Microwave Ablation, Multiparametric Magnetic Resonance Imaging - Prostate Carcinoma | Not applicable | Completed | University of Southern California | 1 | 2023-11-10 | 2025-11-28 |
| Tumor Heterogeneity of Renal Tumors Assessed by Multiparametric MRI With Direct Radiological-histopathological Correlation: an Explorative Study mpMRI - Kidney Cancers | Not applicable | Completed | University of Zurich | 9 | 2023-08-02 | 2026-07-20 |
| Assessment of Renal Function by Multiparametric MRI mpMRI - Renal Impairment | Early Phase 1 | Completed | University of Zurich | 46 | 2023-07-25 | 2025-12-09 |
| PSMA-Targeted 18F-DCFPyL PET/MRI for the Detection of Prostate Cancer Fluorine F 18 DCFPyL, Gadobenate Dimeglumine, Gadobutrol - Prostate Carcinoma | Phase 2 | Withdrawn | Northwestern University | 2023-06-17 | 2025-10-21 | |
| Multicentric Evaluation of the True Negative Predictive Value of Multiparametric MRI for the Detection of Prostate Cancer Using Cystoprostatectomy Specimen as Reference mpMRI - Prostate Cancer | Not applicable | Completed | Institut Paoli-Calmettes | 12 | 2023-06-13 | 2026-10-14 |
| rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Early Phase 1 | Recruiting | Northwestern University | 40 | 2023-06-07 | 2026-07-02 |
| Prostate Cancer Prevention Clinic for Men With Risk of Familial Prostate Cancer Panel sequencing, whole exome sequencing, whole genome sequencing - Prostate Cancer, Familial Prostate Cancer | Not applicable | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 300 | 2023-02-01 | 2023-01-12 |
| Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer mpMRI - Prostate Cancer | Not applicable | Recruiting | National Cancer Institute (NCI) | 508 | 2022-11-18 | 2026-10-16 |
| MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer MRI-Guided Transurethral Ultrasound Ablation, Questionnaire Administration, Digital Rectal Examination - Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Recruiting | Mayo Clinic | 100 | 2022-04-06 | 2026-07-22 |
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases Computed Tomography, 18F-FMAU, Multiparametric Magnetic Resonance Imaging - Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | Early Phase 1 | Completed | University of Southern California | 10 | 2021-02-15 | 2024-05-24 |
| Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy PET Scan, [18F]PSMA-1007 Injection, Sodium MRI - Prostate Cancer, Prostate Adenocarcinoma | Phase 2 | Completed | Glenn Bauman | 16 | 2021-02-04 | 2026-09-18 |
| FDG and FDOPA PET Demonstration of Functional Brain Abnormalities Positron Emission Tomography, Computed Tomography, Multiparametric Magnetic Resonance Imaging Scan - Glioblastoma | Early Phase 1 | Unknown | University of Virginia | 5 | 2020-03-15 | 2020-03-24 |
| MRI and Blood Biomarkers for the Prediction of Neurocognitive Decline Following Brain Radiation Biospecimen Collection, Magnetic Resonance Imaging, Multiparametric Magnetic Resonance Imaging - Brain Neoplasm | Terminated | M.D. Anderson Cancer Center | 9 | 2019-08-22 | 2026-04-22 |
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Prostatic Neoplasms (17) · Brain Neoplasms (2) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Disease (1) · Disease Progression (1) · Driving Under the Influence (1) · Genetic Predisposition to Disease (1) · Glioblastoma (1) · Glioma (1) · Hypertension, Portal (1) · Kidney Neoplasms (1) · Liver Cirrhosis (1) · Lung Neoplasms (1)
National Cancer Institute (NCI) (3) · Jonsson Comprehensive Cancer Center (2) · Northwestern University (2) · University of Southern California (2) · University of Zurich (2) · Assiut University (1) · Emory University (1) · Glenn Bauman (1) · Heinrich-Heine University, Duesseldorf (1) · Icahn School of Medicine at Mount Sinai (1) · Institut Paoli-Calmettes (1) · Lille Catholic University (1) · M.D. Anderson Cancer Center (1) · Mansoura University (1) · Mayo Clinic (1)
United States (16) · Egypt (2) · Switzerland (2) · Canada (1) · China (1) · Denmark (1) · France (1) · Netherlands (1)
Ahmed Mosbah (1) · Alan C Lee (1) · Amar Kishan (1) · Amr Darwish, Lecturer (1) · Andre Luis Abreu, MD (1) · Ashley E Ross (1) · Bachir Taouli, MD (1) · Bijoy Kundu, PhD (1) · Caroline Chung (1) · Dagmar Wieczorek (1) · David A Woodrum, MD, PhD (1) · David M Schuster, MD, FACR (1) · Deborah E Citrin, M.D. (1) · Edward M Schaeffer, MD/PhD (1) · Fatima Karzai, M.D. (1)
PMID 31000430, PMID 33023952, PMID 39427924, PMID 40177325, PMID 40906535, PMID 41014103, PMID 41833067
P30CA014089 (2), P30CA060553 (2), P30CA138292 (1), R01CA238379 (1), R01DK113272 (1), U01CA113913 (1)