6 completed, 3 unknown, 1 not yet recruiting. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 6, Unknown 3, Not yet recruiting 1 |
Follow Mitoxantrone: new trials by email Literature Review of Mitoxantrone trials Research Report on Mitoxantrone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery mitoxantrone hydrochloride injection - Papillary Thyroid Cancer | Phase 4 | Not yet recruiting | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 114 | 2026-02-01 | 2026-01-21 |
| A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia ATO, RIF, ATRA - Childhood Acute Promyelocytic Leukemia | Phase 4 | Completed | South China Children's Leukemia Group | 176 | 2011-09-01 | 2022-05-10 |
| 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia high dose ARA-C, standard dose ARA-C - Acute Myeloid Leukemia | Phase 4 | Unknown | National Research Center for Hematology, Russia | 245 | 2010-01-01 | 2014-04-07 |
| Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Mitoxantrone - Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorders | Phase 4 | Unknown | Xuanwu Hospital, Beijing | 50 | 2009-03-01 | 2013-12-27 |
| Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005) ATRA, Idarubicina, Mitoxantrone - Acute Promyelocytic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 300 | 2005-07-01 | 2014-10-28 |
| Treatment of High Risk Adult Acute Lymphoblastic Leukemia Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2003-01-01 | 2020-04-07 |
| A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease) Mitoxantrone - Neuromyelitis Optica, Myelitis, Transverse | Phase 4 | Completed | State University of New York at Buffalo | 5 | 2001-08-01 | 2020-12-28 |
| AIDA2000 - Risk-Adapted Therapy for Patients With Acute Promyelocytic Leukemia all-trans retinoid acid, idarubicin, mitoxantrone - Leukemia, Promyelocytic, Acute | Phase 4 | Unknown | Technische Universität Dresden | 80 | 2000-01-01 | 2011-07-11 |
| LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2000-01-01 | 2010-01-05 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) Asparaginase, Vincristine, Daunorubicin, Adriamycin - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 720 | 1993-04-01 | 2023-03-17 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Leukemia, Promyelocytic, Acute (2) · Neuromyelitis Optica (2) · Autoimmune Diseases of the Nervous System (1) · Demyelinating Autoimmune Diseases, CNS (1) · Leukemia, Myeloid, Acute (1) · Myelitis, Transverse (1) · Recurrence (1) · Thyroid Cancer, Papillary (1)
PETHEMA Foundation (3) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (1) · Goethe University (1) · National Research Center for Hematology, Russia (1) · South China Children's Leukemia Group (1) · State University of New York at Buffalo (1) · Technische Universität Dresden (1) · Xuanwu Hospital, Beijing (1)
China (3) · Spain (3) · Germany (2) · Poland (1) · Russia (1) · United States (1) · Uruguay (1)
Bianca Weinstock-Guttman, M.D. (1) · Dieter Hoelzer, MD, PhD (1) · Gerhard Ehninger, MD (1) · Huiqing Dong, Doctor (1) · Lowenberg Bob, Dr (1) · San Miguel Miguel Angel, Dr (1) · Valeriy G Savchenko (1) · Vellenga Edo, Dr (1) · Xue-Qun Luo, professor (1)
PMID 16831964, PMID 20393132, PMID 21148082, PMID 24752047, PMID 25314773, PMID 25975975, PMID 28584252, PMID 35760920, PMID 39781038