24 unknown, 16 completed, 14 terminated, 11 recruiting. 57 Not applicable, 10 Phase 2, 5 Phase 3, 4 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Value of Ultrasound-Guided Microwave Ablation for Breast Fibroadenoma microwave ablation - Breast Fibroadenoma | Not applicable | Not yet recruiting | Assiut University | 45 | 2026-08-01 | 2026-07-22 |
| Safety and Efficacy of Microwave Ablation Alone Versus Microwave Ablation Combined With Chemical Ablation in the Treatment of Uterine Fibroids: A Prospective, Multicenter Study Microwave ablation combined with chemical ablation, Microwave ablation - Uterine Fibroids (UF), Microwave Ablation | Not applicable | Not yet recruiting | Peking University Aerospace Center Hospital | 248 | 2026-08-01 | 2026-08-10 |
| Percutaneous Thermo-ablation for the Treatment of Prostate Cancer Oligometastatasis (TA-P-OLIM) Thermal ablation - Oligometastatic Prostate Cancer (OMPC), Prostate Cancer (Adenocarcinoma) | Withdrawn | University Hospital, Ghent | 2026-05-10 | 2026-05-13 | ||
| Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases 1.0% IP-001 for Injection, a 10 mg/mL solution of IP-001 in water, 1.0% IP-001 for Injection, a 1 mg/mL solution of IP-001 in water., Microwave (thermal) tumor ablation - Colorectal Cancer (CRC), Colon Cancer Liver Metastases | Phase 2 / Phase 3 | Not yet recruiting | Immunophotonics, Inc. | 717 | 2026-05-01 | 2026-01-07 |
| Microwave Ablation of Uterine Fibroids microwave ablation - Uterine Fibroids (Leiomyoma) | Active not recruiting | Turku University Hospital | 100 | 2026-05-01 | 2026-08-21 | |
| Microwave Ablation Plus Tislelizumab and Docetaxel in Advanced NSCLC After First-Line Immunotherapy Failure Tislelizumab, Docetaxel, Microwave ablation - NSCLC (Non-small Cell Lung Cancer), NSCLC (Advanced Non-small Cell Lung Cancer) | Phase 2 | Recruiting | Tianjin Medical University Cancer Institute and Hospital | 20 | 2026-05-01 | 2026-04-14 |
| Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety Microwave Ablation - Venous Malformations, Arteriovenous Malformations | Not applicable | Not yet recruiting | Chengdu University of Traditional Chinese Medicine | 150 | 2026-03-01 | 2026-02-11 |
| Efficacy of Ultrasound Guided Microwave Ablation in the Treatment of Uterine Fibroids. Ultrasound-Guided Percutaneous Microwave Thermal Ablation - Uterine Fibroids (Leiomyoma), Symptomatic Uterine Leiomyoma | Not applicable | Not yet recruiting | Jihad Hussien Mohamed Mahmoud | 20 | 2025-11-30 | 2025-11-19 |
| Clinical Investigation Evaluating the Performance, Safety and Clinical Benefit of the Endowave FlexAblate™ Microwave Ablation System in Patients Undergoing Lung Ablation Procedures. Microwave Ablation - Lung Cancer | Not applicable | Recruiting | Endowave Ltd. | 43 | 2025-10-24 | 2026-04-09 |
| Transbronchial MWA for Pulmonary Tumors Microwave ablation - Lung Cancer | Not applicable | Recruiting | Shanghai Chest Hospital | 15 | 2025-05-12 | 2025-07-18 |
| A Study of Microwave Ablation Combined With Immunotherapy ± Anti-angiogenic Drugs in the Treatment of Solid Tumors Adebrelimab, Apatinib, microwave ablation - Solid Tumor | Phase 2 | Not yet recruiting | Beidahuang Industry Group General Hospital | 60 | 2024-08-05 | 2024-08-05 |
| Clinical Effectiveness of Microwave Ablation Using Starwave Microwave Generator for Hepatic Malignancies Starwave Microwave Ablation System, Microwave Ablation, Ultrasound-CT fusion guidance system - Liver Malignant Tumors | Not applicable | Recruiting | Seoul National University Hospital | 128 | 2024-04-30 | 2026-04-13 |
| Microwave Ablation in the Treatment of Early-stage Unifocal Invasive Breast Cancer Microwave Ablation - Breast Cancer | Not applicable | Unknown | The First Affiliated Hospital with Nanjing Medical University | 77 | 2024-02-25 | 2024-03-01 |
| Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT Radiofrequency ablation alone, Microwave ablation - Ablation Techniques, RFA, Ablation Treatment | Not applicable | Active not recruiting | The University of Hong Kong | 50 | 2023-12-05 | 2026-09-21 |
| Prostate Resection After Microwave Ablation (PRAMA) Biospecimen Collection, Microwave Ablation, Multiparametric Magnetic Resonance Imaging - Prostate Carcinoma | Not applicable | Completed | University of Southern California | 1 | 2023-11-10 | 2025-11-28 |
| Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial Stereotactic Ablative Radiotherapy, Resection, Microwave Ablation - Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 | Phase 2 | Recruiting | Alliance for Clinical Trials in Oncology | 146 | 2023-10-09 | 2026-10-02 |
| Clinical Feasibility of Microwave Ablation Using Two Channel Microwave Generator and Two Antennas for Small Hepatocellular Carcinoma Microwave ablation - Hepatocellular Carcinoma | Not applicable | Completed | Seoul National University Hospital | 20 | 2023-09-18 | 2026-04-13 |
| 90Y Transarterial Radioembolization Versus Microwave Ablation in Small Hepatocellular Carcinoma With Hypoalbuminemia Therasphere 90Y, Microwave Ablation - Carcinoma, Hepatocellular | Not applicable | Recruiting | Ochsner Health System | 50 | 2023-08-08 | 2025-08-03 |
| Non Surgical Treatment (Microwave Ablation) of Breast Cancer Microwave ablation - Breast Cancer Stage I | Not applicable | Unknown | University Medical Center Groningen | 15 | 2023-07-01 | 2023-06-02 |
| Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal) Focal Therapy for Prostate Cancer - Prostate Cancer | Recruiting | Singapore General Hospital | 500 | 2023-05-06 | 2024-07-08 |
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Carcinoma, Hepatocellular (19) · Lung Neoplasms (11) · Carcinoma, Non-Small-Cell Lung (10) · Liver Neoplasms (10) · Breast Neoplasms (6) · Colorectal Neoplasms (6) · Neoplasm Metastasis (6) · Leiomyoma (4) · Neoplasms (4) · Prostatic Neoplasms (3) · Sarcoma (3) · Adenocarcinoma (1) · Arteriovenous Malformations (1) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma, Renal Cell (1)
Chinese PLA General Hospital (8) · Ethicon, Inc. (7) · Chinese University of Hong Kong (3) · Karolinska Institutet (3) · Amsterdam UMC, location VUmc (2) · Assiut University (2) · RenJi Hospital (2) · Seoul National University Hospital (2) · Shandong Provincial Hospital (2) · Shanghai Chest Hospital (2) · Shanghai Zhongshan Hospital (2) · The First Affiliated Hospital with Nanjing Medical University (2) · Wake Forest University Health Sciences (2) · Alliance for Clinical Trials in Oncology (1) · Aurimas Macionis (1)
China (34) · United States (17) · Netherlands (6) · South Korea (4) · Hong Kong (3) · Sweden (3) · Belgium (2) · Canada (2) · France (2) · Singapore (2) · United Kingdom (2) · Egypt (1) · Finland (1) · Germany (1) · Greece (1)
Ping Liang, Doctor (4) · Dionisios Vrochides, MD PhD (2) · Jacob Freedman, MD, PhD (2) · Andre Luis Abreu, MD (1) · Ari Cohen, MD (1) · Baki Topal, MD, PhD (1) · Bo Zhai, Doctor (1) · Bradley Pua, MD (1) · Brian Van Tine, M.D., Ph.D. (1) · Chang Chen, Dr (1) · Charing CN Chong, MBChB (1) · Constantinos Sofocleous, MD, PhD, FSIR, FCIRSE (1) · Derek L West, MD (1) · Diane M Beatty, PhD (1) · Errol Prens, MD, PhD (1)
PMID 29333159, PMID 10207464, PMID 12049862, PMID 12594571, PMID 12623635, PMID 12893895, PMID 16305946, PMID 17877488, PMID 18355796, PMID 18852074, PMID 19241423, PMID 19304921, PMID 19453695, PMID 19560026, PMID 19926229, PMID 20175033, PMID 20605397, PMID 21966941, PMID 22173160, PMID 22190656, PMID 22353262, PMID 22438360, PMID 22544225, PMID 22766484, PMID 23096937, PMID 23216261, PMID 23399463, PMID 23482806, PMID 24410841, PMID 24935203, PMID 25139639, PMID 25516662, PMID 25559415, PMID 25572816, PMID 26148053, PMID 28654336, PMID 28842651, PMID 28847194, PMID 29487221, PMID 29511672, PMID 29962870, PMID 30111304, PMID 31179781, PMID 31939434, PMID 32356159, PMID 32792427, PMID 33102398, PMID 33471820, PMID 33556187, PMID 33615957
2025 (1), P30CA014089 (1)