5 completed, 3 recruiting, 1 not yet recruiting. 3 Not applicable, 3 Phase 3, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 3 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Metfomin: new trials by email Literature Review of Metfomin trials Research Report on Metfomin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity Metformin, Placebo - Osteoarthritis (OA) of the Knee | Early Phase 1 | Recruiting | The University of Hong Kong | 100 | 2026-08-30 | 2026-08-18 |
| Metformin Treatment for Children With Obesity-associated Asthma Metfomin, Placebo - Obesity-associated Asthma | Phase 3 | Not yet recruiting | Prof Ibrahim Janahi | 182 | 2026-06-01 | 2026-06-03 |
| Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients Myo-inositol, Folic Acid, Alpha Lipoic Acid - Poly Cystic Ovary Syndrome | Phase 3 | Recruiting | Beni-Suef University | 180 | 2026-03-10 | 2026-06-05 |
| Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis Metfomin - Knee Arthritis Osteoarthritis | Not applicable | Completed | Horus University | 80 | 2026-01-01 | 2026-07-31 |
| The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment Metfomin - Mild Cognitive Impairment, Overweight or Obesity | Phase 1 / Phase 2 | Recruiting | Fudan University | 54 | 2025-09-01 | 2026-02-09 |
| The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity Empagliflozin (oral), Dapagliflozin (DAPA), Metfomin - Type 2 Diabetes, Obese Diabetics | Phase 4 | Completed | Erbil Polytechnic University | 260 | 2025-07-15 | 2026-03-17 |
| The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients N-acetyl cysteine, Metfomin - Polycystic Ovary Syndrome | Phase 3 | Completed | Cairo University | 102 | 2025-03-01 | 2026-10-21 |
| Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen Metfomin, tamoxifen, Placebo matching Metformin - Breast Cancer, Endometrial Hyperplasia and Endometrial Cancers | Not applicable | Completed | Uruk University | 60 | 2024-01-02 | 2025-09-12 |
| Preservation of Beta-cell Function in Type 2 Diabetes Mellitus Metformin, Insulin, Metfomin - Type 2 Diabetes Mellitus | Not applicable | Completed | University of Texas Southwestern Medical Center | 58 | 2003-11-01 | 2017-12-14 |
Diabetes Mellitus, Type 2 (2) · Breast Neoplasms (1) · Cognitive Dysfunction (1) · Endometrial Hyperplasia (1) · Endometrial Neoplasms (1) · Obesity (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Overweight (1) · Polycystic Ovary Syndrome (1)
Beni-Suef University (1) · Cairo University (1) · Erbil Polytechnic University (1) · Fudan University (1) · Horus University (1) · Prof Ibrahim Janahi (1) · The University of Hong Kong (1) · University of Texas Southwestern Medical Center (1) · Uruk University (1)
Egypt (3) · Iraq (2) · China (1) · Hong Kong (1) · Qatar (1) · United States (1)
Amr Z Abdelhamid, PhD (1) · Eglal A Mostafa Bassiouny, PhD (1) · Ghasak Kais Abdulhussain, BSc, MSc, PhD (Pharmacology) (1) · Ibrahim Janahi, MD, FCCP, FRCPCH (1) · Ildiko Lingvay, MD (1) · Philip Raskin, MD (1) · Samar F Farid, PhD (1) · Xiaoming Tao (1)
PMID 17362692, PMID 19592630, PMID 22723578, PMID 23897684, PMID 26981941, PMID 27440829, PMID 30067158, PMID 30311716, PMID 31018107, PMID 32855502, PMID 34575958