7 completed, 1 terminated, 1 unknown. 4 Phase 2, 2 Phase 1, 2 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
Follow Megestrol: new trials by email Literature Review of Megestrol trials Research Report on Megestrol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Megestrol Acetate in Grade 2 Endometrioid Endometrial Cancer Megestrol Acetate - Endometrial Cancer | Phase 1 | Terminated | Sunnybrook Health Sciences Centre | 5 | 2022-07-05 | 2023-11-03 |
| iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children Megestrol Acetate, iKanEat Behavioral Intervention - Feeding Behavior, Feeding Disorder of Infancy or Early Childhood | Phase 4 | Completed | University of Kansas Medical Center | 70 | 2019-08-15 | 2025-09-10 |
| Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care. Mirtazapine, Megestrol - Cachexia; Cancer, Anorexia | Phase 2 | Completed | University of Sao Paulo | 52 | 2019-03-26 | 2023-07-07 |
| the Efficacy and Safety of 5-HT3 Receptor Antagonist, Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy Megestrol, 5-HT3 receptor antagonist, dexamethasone - Tumor, Chemotherapy-induced Nausea and Vomiting | Phase 2 | Unknown | Henan Cancer Hospital | 120 | 2018-09-07 | 2020-06-12 |
| Phenytoin for Memory Impairment Secondary to Megestrol Phenytoin 200 mg capsule, Megestrol 800 mg liquid, Phenytoin-matched Placebo capsule - Cognitive Impairment | Phase 4 | Completed | University of Texas Southwestern Medical Center | 21 | 2015-07-01 | 2019-09-09 |
| Phase 1 Study of Daewon-ES(B) & Megace in Healthy Male Volunteers Under Fed Condition Megace 800mg/20ml, DW-ES(B) 625mg/5ml - Healthy | Phase 1 | Completed | Daewon Pharmaceutical Co., Ltd. | 28 | 2012-04-01 | 2013-01-23 |
| Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age Amitriptyline, Placebo, Megestrol - Chronic Oral Food Refusal | Phase 2 | Completed | Ann Davis, PhD, MPH, ABPP | 21 | 2010-08-01 | 2016-08-15 |
| Metronomic Chemotherapy by Cyclophosphamide Versus Megestrol in Palliative Cancer CYCLOPHOSPHAMIDE, MEGESTROL - Cancer | Phase 2 | Completed | Centre Oscar Lambret | 88 | 2009-09-25 | 2026-09-17 |
| Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting megestrol, Exercise - Acquired Immunodeficiency Syndrome, HIV Wasting Syndrome | Not applicable | Completed | National Center for Research Resources (NCRR) | 69 | 1995-06-01 | 2005-06-24 |
Neoplasms (3) · Acquired Immunodeficiency Syndrome (1) · Anorexia (1) · Cachexia (1) · Cognitive Dysfunction (1) · Communicable Diseases (1) · Endometrial Neoplasms (1) · Feeding Behavior (1) · HIV Infections (1) · HIV Wasting Syndrome (1) · Immune System Diseases (1) · Rare Diseases (1) · Virus Diseases (1) · Vomiting (1)
Ann Davis, PhD, MPH, ABPP (1) · Centre Oscar Lambret (1) · Daewon Pharmaceutical Co., Ltd. (1) · Henan Cancer Hospital (1) · National Center for Research Resources (NCRR) (1) · Sunnybrook Health Sciences Centre (1) · University of Kansas Medical Center (1) · University of Sao Paulo (1) · University of Texas Southwestern Medical Center (1)
United States (3) · Brazil (1) · Canada (1) · China (1) · France (1) · South Korea (1)
Ann Davis, Ph.D., MPH, ABPP (1) · Bojana Djordjevic, MD (1) · Danielle Vicus, MD, MSc (1) · E. Sherwood Brown, MD, PhD (1) · Jamie Hayden Von Roenn (1) · Nereida KC Lima, MD, PhD (1) · Ning Li (1) · Suxia Luo (1)
R21HD066629 (1)