29 completed, 13 unknown, 4 recruiting, 2 not yet recruiting. 31 Not applicable, 6 Phase 4, 5 Phase 3, 3 Early Phase 1, 1 Phase 1.
Follow Local Anesthesia: new trials by email Literature Review of Local Anesthesia trials Research Report on Local Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG) - Total Knee Arthroplasty (TKA) | Phase 1 / Phase 2 | Recruiting | University of Chicago | 150 | 2026-03-11 | 2026-06-26 |
| Silencing Neuroma Pain-Botulinum Toxin Versus Local Anesthetic Injection Botulinium toxin type A injection, Local Anesthesia - Pain Management, Pain | Not applicable | Not yet recruiting | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 100 | 2026-02-15 | 2026-02-25 |
| Hysteroscopy Anesthesia for Relief of Pain Local paracervical Anesthesia, Placebo - Pain Management, Outpatient Hysteroscopy | Not applicable | Not yet recruiting | Maimónides Biomedical Research Institute of Córdoba | 70 | 2025-09-06 | 2025-09-17 |
| Photobiomodulation and Tooth Analgesia Photobiomodulation, Topical Benzocaine, Local Anesthesia - Dental Anaesthesia, Dental Pain | Not applicable | Recruiting | University of Maryland, Baltimore | 200 | 2025-07-07 | 2026-08-12 |
| A Study of Changes to Prostate Procedures Prostate Biopsy, Local anesthesia - Prostate Cancer | Phase 3 | Recruiting | Memorial Sloan Kettering Cancer Center | 800 | 2025-05-19 | 2026-09-15 |
| Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia. Pectoral Nerve Block, Local Anesthesia - Pain, Pain Management | Not applicable | Completed | Faculdade de Ciências Médicas de Minas Gerais | 124 | 2025-04-15 | 2026-06-09 |
| Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery Local Anesthesia, Laparoscopic Transversus Abdominis Plane block - Oncologic Surgery, Cancer | Not applicable | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 48 | 2025-02-05 | 2025-09-18 |
| General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients General Anesthesia, Local anesthesia - General Anesthesia, Dexmedetomidine | Not applicable | Completed | Tanta University | 60 | 2024-05-01 | 2026-02-17 |
| The Ideal Local Anesthetic for Intraperitoneal Gallbladder Bed Infiltration Following Laparoscopic Cholecystectomy Local Anesthesia - Cholecystectomy, Laparoscopic, Pain Management | Not applicable | Completed | Pakistan Air Force (PAF) Hospital Islamabad | 90 | 2024-01-01 | 2024-09-20 |
| Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures TICK-B, TKTX-Cream, TICK-B and TKTX-C - Pain | Not applicable | Unknown | Uppsala University | 160 | 2023-12-15 | 2024-03-28 |
| TENS for Pain Relief During Fusion-Guided Prostate Biopsy Transcutaneous Electrical Nerve Stimulation (TENS), Sham Transcutaneous Electrical Nerve Stimulation (Sham TENS), Local Anesthesia - Prostate Cancer, Prostate Biopsy | Not applicable | Completed | Medical University of Gdansk | 84 | 2023-12-01 | 2026-01-09 |
| Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia Local anesthesia, General anesthesia - Wisdom Teeth Extraction or Jaw Implant | Unknown | Zoya Haitov Ben Zikri | 46 | 2023-09-01 | 2024-04-24 | |
| Effect of Erector Spinae Plane Block in Patients Scheduled for Kyphoplasty Erector spinae plane block, Local anesthesia - Erector Spinae Plane Block | Completed | Bozyaka Training and Research Hospital | 61 | 2023-07-25 | 2025-05-06 | |
| Oocyte Retrieval and Virtual Reality (REVPO) Hypnotic relaxation induced by virtual reality (device), local anesthesia - Oocyte Retrieval, Pain | Not applicable | Completed | University Hospital, Clermont-Ferrand | 150 | 2021-06-09 | 2024-09-19 |
| Postoperative Pain Difference for 'IV Paracetamol' and TAP Block' in Acute Cholecystitis Intravenous Infusion, Local anesthesia - Transversus Abdominis Plane (TAP) Block | Phase 3 | Unknown | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | 42 | 2021-03-15 | 2021-03-03 |
| Axillary Block or Wide-awake Local Anesthesia for Complex Regional Pain Syndrome (CRPS) Following Common Hand Surgeries Surgery for Dupuytren contracture (DC), DeQuervain tenosynovitis (DQS), carpal tunnel syndrome (CTS), or trigger finger (TF), Regional Anesthesia, Local Anesthesia - CRPS, Walant | Completed | Ankara University | 98 | 2021-01-01 | 2025-03-10 | |
| Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis local anesthesia - Root Canal Infection | Not applicable | Completed | Ain Shams University | 160 | 2021-01-01 | 2021-10-07 |
| Effects of Anesthetic Methods on Hepatic Cancer Cell Function in Vitro general anesthesia, local anesthesia - Hepatocellular Carcinoma | Not applicable | Completed | RenJi Hospital | 35 | 2020-08-20 | 2021-01-08 |
| Use of Perioperative Pain Blocks In Urological Surgery Bupivacain, Ultrasound-guided transversus abdominus plane block, Laparoscopic-guided transversus abdominus plane block - Pain, Postoperative, Nerve Block | Phase 3 | Completed | Icahn School of Medicine at Mount Sinai | 148 | 2019-11-11 | 2024-03-12 |
| Should Maxillary Buccal Infiltration Anesthesia be Given in a Closed Mouth Technique? Local anesthesia - Anesthesia, Local, Pain Control | Not applicable | Completed | University of Jordan | 120 | 2019-04-29 | 2021-01-27 |
Showing 20 of 49. Sign in to see all of them.
Agnosia (11) · Pain (9) · Pain, Postoperative (5) · Breast Neoplasms (3) · Prostatic Neoplasms (3) · Anxiety Disorders (2) · Chronic Pain (2) · Neoplasms (2) · Stroke (2) · Alveolar Bone Loss (1) · Arteriovenous Fistula (1) · Biliary Tract Neoplasms (1) · Bites and Stings (1) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1)
Bakirkoy Dr. Sadi Konuk Research and Training Hospital (2) · Mayo Clinic (2) · RenJi Hospital (2) · Ain Shams University (1) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Ankara University (1) · Armed Forces Institute of Urology, Rawalpindi (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Tiantan Hospital (1) · Bozyaka Training and Research Hospital (1) · Cairo University (1) · Campus Bio-Medico University (1) · Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Copenhagen University Hospital, Rigshospitalet (1)
United States (11) · China (3) · Turkey (Türkiye) (3) · Brazil (2) · Canada (2) · Egypt (2) · France (2) · Pakistan (2) · Belgium (1) · Denmark (1) · Iraq (1) · Israel (1) · Italy (1) · Jordan (1) · Netherlands (1)
Ahmad El-Ma'aita, PhD (1) · Ahmed Abdel Rahman Hashem (1) · Andre Chen, Msc (1) · Andrew Elimian, MD (1) · Camille Valdeyron (1) · Casey Allen, MD (1) · Christine Watremez, MD, PhD (1) · Christophe Poncelet, MD PhD (1) · Clark C Otley, MD (1) · Elena Cervino, Msc (1) · Fabio Costa (1) · Hassan M Ali, Lecturer (1) · Helena Francisco, Msc (1)
PMID 35857365, PMID 40772525, PMID 17368248, PMID 17571915, PMID 17724727, PMID 20332307, PMID 21238825, PMID 24165901, PMID 25509976, PMID 26885872, PMID 28079776, PMID 28436307, PMID 28562733, PMID 29340574, PMID 29739917, PMID 29793595, PMID 30926686, PMID 32570188, PMID 32712962, PMID 35122442, PMID 35289396, PMID 35611933, PMID 35699807, PMID 37386519, PMID 37888047, PMID 39251366, PMID 39420491, PMID 39685488, PMID 39971386, PMID 7646610