26 completed, 10 unknown, 7 terminated, 6 recruiting. 27 Phase 2, 20 Phase 3, 6 Not applicable, 5 Phase 4, 4 Phase 1.
Follow Intravenous immunoglobulin: new trials by email Literature Review of Intravenous immunoglobulin trials Research Report on Intravenous immunoglobulin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis Therapeutic Plasma Exchange, Rituximab, Intravenous immunoglobulin - Idiopathic Pulmonary Fibrosis | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 52 | 2026-12-01 | 2026-10-20 |
| Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haploidentical Hematopoietic Stem Cell Transplantation Intravenous Immunoglobulin, Dexamethasone, Mononuclear Cells - Leukemia, Lymphoma | Phase 2 | Not yet recruiting | Hematology department of the 920th hospital | 60 | 2026-07-03 | 2026-07-14 |
| Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below intravenous immunoglobulin - Bronchopulmonary Dysplasia | Phase 2 | Recruiting | International Peace Maternity and Child Health Hospital | 29 | 2026-04-23 | 2026-07-23 |
| Comparison of the Efficacy and Safety of Immunoadsorption and Intravenous Immunoglobulin for Guillain-Barre Syndrome immunosorbent column, intravenous immunoglobulin - Guillain-Barre Syndrome | Not applicable | Not yet recruiting | The First Affiliated Hospital of Zhengzhou University | 204 | 2026-01-01 | 2025-03-12 |
| Telitacicept for Refractory Chronic Inflammatory Demyelinating Polyneuropathy Conventional Therapy, Telitacicept - Refractory Chronic Inflammatory Demyelinating Polyneuropathy | Not applicable | Active not recruiting | Sichuan Academy of Medical Sciences | 76 | 2025-09-26 | 2026-05-19 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) Intravenous immunoglobulin, Trimethoprim / Sulfamethoxazole, Amoxicillin clavulanic acid - Myeloma, Non-Hodgkin's Lymphoma | Phase 2 / Phase 3 | Recruiting | Monash University | 900 | 2025-05-06 | 2025-10-07 |
| IVIG Trial for the Treatment of Bronchopulmonary Dysplasia intravenous immunoglobulin - Bronchopulmonary Dysplasia | Phase 2 | Recruiting | International Peace Maternity and Child Health Hospital | 20 | 2025-04-12 | 2026-05-27 |
| IVIG in Painful Sensory Neuropathy Intravenous immunoglobulin, Placebo - Sensory Neuropathy, Small Fiber Neuropathy | Phase 4 | Not yet recruiting | Sorlandet Hospital HF | 20 | 2024-02-01 | 2023-12-27 |
| A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG Treatment ANAKINRA, Intravenous immunoglobulin - Kawasaki Disease | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 84 | 2023-10-20 | 2024-02-28 |
| Prednisone Plus IVIg vs. Prednisone for ITP During Pregnancy Prednisone, IVIg - Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 100 | 2023-10-19 | 2024-08-29 |
| IVIg Plus Low Dose rhTPO for ITP in Pregnancy intravenous immunoglobulin plus low dose recombinant human thrombopoietin (rhTPO), intravenous immunoglobulin - Immune Thrombocytopenia, Pregnancy Related | Phase 2 | Unknown | Peking University People's Hospital | 50 | 2023-01-01 | 2022-12-02 |
| Two Regimens of IVIG in the Treatment of Newly Diagnosed ITP in Children intravenous immunoglobulin - Newly Diagnosed Immune Thrombocytopenia in Children, First Line Treatment | Phase 4 | Unknown | Fujian Medical University Union Hospital | 580 | 2022-10-06 | 2024-05-16 |
| Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS) Methylprednisolone, intravenous immunoglobulin, Tocilizumab - Severe Fever With Thrombocytopenia Syndrome | Phase 4 | Unknown | Qin Ning | 350 | 2022-08-19 | 2023-07-21 |
| Phase III Clinical Study of NPB-01 in Patients With Autoimmune Encephalitis NPB-01, NPB-01-ME - Autoimmune Encephalitis | Phase 3 | Unknown | Nihon Pharmaceutical Co., Ltd | 40 | 2022-03-03 | 2022-12-01 |
| Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx Imlifidase, PLEX, IVIg - Kidney Transplantation in Highly Sensitized Patients | Phase 3 | Completed | Hansa Biopharma AB | 64 | 2021-10-14 | 2026-04-30 |
| Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients intravenous immunoglobulin - Burn Shock | Phase 2 / Phase 3 | Completed | Cairo University | 30 | 2021-10-10 | 2022-11-15 |
| IVIG Versus Plasmapheresis in the Treatment of Guillian Barrie Syndrome Patients plasmapheresis device, Intravenous immunoglobulin - Guillain-Barre Syndrome | Phase 2 / Phase 3 | Completed | Assiut University | 81 | 2021-09-01 | 2023-04-06 |
| Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis Infliximab, Intravenous Immunoglobulin Therapy, Prednisone - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Phase 2 | Terminated | ECOG-ACRIN Cancer Research Group | 1 | 2021-01-07 | 2026-09-29 |
| The Efficacy of Intravenous Immunoglobulin Therapy for Severe 2019-nCoV Infected Pneumonia Intravenous Immunoglobulin, Standard care - 2019-nCoV | Phase 2 / Phase 3 | Unknown | Peking Union Medical College Hospital | 80 | 2020-02-10 | 2020-02-07 |
| A Clinical Study of ANX005 and IVIG in Subjects With Guillain Barré Syndrome (GBS) ANX005, Intravenous immunoglobulin - Guillain-Barré Syndrome | Phase 1 | Completed | Annexon, Inc. | 14 | 2020-01-29 | 2021-08-11 |
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Purpura, Thrombocytopenic, Idiopathic (5) · Autoimmune Diseases of the Nervous System (3) · Guillain-Barre Syndrome (3) · Polyradiculoneuropathy, Chronic Inflammatory Demyelinating (3) · Small Fiber Neuropathy (3) · Autoimmune Diseases (2) · Bronchopulmonary Dysplasia (2) · Infections (2) · Kidney Failure, Chronic (2) · Leukemia (2) · Lymphoma (2) · Mucocutaneous Lymph Node Syndrome (2) · Neuromyelitis Optica (2) · Psychotic Disorders (2) · Schizophrenia (2)
Nihon Pharmaceutical Co., Ltd (4) · Assiut University (2) · International Peace Maternity and Child Health Hospital (2) · Peking University People's Hospital (2) · University of Cambridge (2) · Academisch Ziekenhuis Maastricht (1) · Ain Shams University (1) · Annexon, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Azienda Socio Sanitaria Territoriale di Mantova (1) · Beth Israel Deaconess Medical Center (1) · Cairo University (1) · Cedars-Sinai Medical Center (1) · Columbia University (1) · Copenhagen University Hospital, Rigshospitalet (1)
United States (20) · China (8) · Japan (5) · Canada (4) · United Kingdom (4) · Denmark (3) · Egypt (3) · Netherlands (2) · Australia (1) · Bangladesh (1) · Brazil (1) · France (1) · Hong Kong (1) · India (1) · Puerto Rico (1)
Fu Xuemei (2) · Alasdair Coles, 01223 762016 (1) · Alasdair Coles, PhD FRCP (1) · Alexander J Clark, MD, FRCPC (1) · Ali Khojasteh, MD (1) · Ann Traynor, MD (1) · Benyan Luo, Ph.D (1) · Betty Diamond, MD (1) · Bevra Hahn, MD (1) · Carlos Rodriguez-Galindo, MD (1) · Catharina G Faber, MD, PhD (1) · Christopher Gibbons, MD (1) · David Simpson, MD (1)
PMID 17091076, PMID 19236457, PMID 21868369, PMID 22882285, PMID 23450336, PMID 24235922, PMID 25090414, PMID 25412569, PMID 25987537, PMID 26009577, PMID 26083430, PMID 27439408, PMID 27591241, PMID 28639937, PMID 28768822, PMID 30116551, PMID 30499734, PMID 30685874, PMID 31174586, PMID 31257724, PMID 32853584, PMID 33568350, PMID 33593867, PMID 33766992, PMID 34715057, PMID 34887657, PMID 35183451, PMID 36626193, PMID 38509495, PMID 41307525, PMID 42309868, PMID 5496482
2014 (1), 2015 (1), 2017 (1), 2018 (1), UG1CA189828 (1)