19 completed, 11 not yet recruiting, 3 recruiting, 2 active not recruiting. 34 Not applicable, 4 Phase 2, 2 Phase 3, 2 Phase 4, 1 Early Phase 1.
Follow Intervention 1: new trials by email Literature Review of Intervention 1 trials Research Report on Intervention 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years Intervention 1, Intervention 2 - Idiopathic Generalized Epilepsy | Not applicable | Not yet recruiting | Oregon Health and Science University | 10 | 2027-02-01 | 2026-10-28 |
| RESCUE: PCSK9 Inhibitors for Carotid Vulnerable Plaque Remodeling Intervention 1, Intervention 3, Intervention 2 - Atherosclerosis Cerebral, Carotid Plaque | Phase 4 | Not yet recruiting | Keqiang Zhao | 120 | 2027-01-01 | 2026-09-15 |
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| Human-AI Uncertainty Callibration for Improved Skin Lesion Segmentation Base Model, FDM - Skin Lesions | Not applicable | Not yet recruiting | Copenhagen Academy for Medical Education and Simulation | 50 | 2026-12-01 | 2026-10-30 |
| Comparative Effects of Virtual Reality and Proprioceptive Neuromuscular Facilitation in Patients With Parkinson's Disease Intervention 1, artificial intelligence - Parkinson Disease | Not applicable | Not yet recruiting | Lahore University of Biological and Applied Sciences | 28 | 2026-11-15 | 2026-11-05 |
| Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Chronic HD Patients? Low-Sodium Dialysate (133 mmol/L), Standard-Sodium Dialysate (139 mmol/L) - Dialysis Dependent Chronic Kidney Disease, Dialysis Patients | Not applicable | Not yet recruiting | Gødstrup Hospital | 25 | 2026-11-01 | 2026-09-15 |
| Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial) Percutaneous transpapillary internal-external biliary drainage, Percutaneous suprapapillary biliary drainage with self-expanding metal stent - Cholangiocarcinoma, Bile Duct Neoplasms | Not applicable | Recruiting | Hospital de Clinicas de Porto Alegre | 84 | 2026-06-24 | 2026-10-01 |
| The Effect of Aromatherapy Massage-Based Sensory Stımulatıon Program on Cognıtıve and Sensory Functıon ın Intensıve Care Patıents Intervention 1, Intervention 2, plasebo group - Cognitive Sensory Perception Level, in Unconscious Patients | Not applicable | Not yet recruiting | Nigde Omer Halisdemir University | 60 | 2026-06-01 | 2026-05-18 |
| School-Based Sensory Processing and Daily Living Skills-Focused Occupational Therapy Program Individual School-Based Occupational Therapy Sessions, Sensory Preparation Using Proprioceptive, Vestibular, and Tactile Input, Task-Oriented Activities of Daily Living Training - Intellectual Disability, Variable, Autism Spectrum Disorder (ASD) | Not applicable | Not yet recruiting | Çankırı Karatekin University | 40 | 2026-05-04 | 2026-04-09 |
| Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing. Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication - Pain Management | Early Phase 1 | Active not recruiting | Future University in Egypt | 24 | 2026-04-05 | 2026-09-16 |
| Artificial Intelligence Education and Climate Awareness in Pregnancy Intervention 1, Control - Climate Change, Maternal Health | Not applicable | Not yet recruiting | Derya Kaya Senol | 82 | 2026-04-01 | 2026-04-21 |
| Effects of Vestibular Rehabilitation and Routine Physical Therapy in Athletes With Post Concussion Syndrome Intervention 1, Control Arm (Conventional Therapy) - Post Concussion Syndrome | Not applicable | Not yet recruiting | Lahore University of Biological and Applied Sciences | 34 | 2026-03-22 | 2026-02-10 |
| EARLY Study: Evaluating the Specificity and Feasibility of the EARLY Biomarker Panel for Ovarian Cancer Detection Intervention 1, Intervention 2 - Ovarian Cancer | Not applicable | Recruiting | Queensland Centre for Gynaecological Cancer | 1500 | 2026-02-01 | 2026-03-24 |
| Comparative Accuracy of Conventional Scan Bodies, Intra-oral Photogrammetry, and Calibrated Scan Flags in Full-Arch Implant Scanning Intervention 1, Intervention 2, Intervention 3 - Accuracy of Different Scanning Techniques | Not applicable | Not yet recruiting | Cairo University | 24 | 2025-12-20 | 2025-10-01 |
| Chair Exercise and Intergenerational Activities in Older Adults With Physio-Cognitive Decline Syndrome Intervention 1 - Cognitive Frailty | Not applicable | Completed | Atma Jaya Catholic University of Indonesia | 100 | 2025-09-24 | 2026-05-04 |
| The Effectiveness of the Polyvagal Theory in Chronic Neck Pain Control, Intervention 1, Intervention 2 - Chronic Neck Pain | Not applicable | Enrolling by invitation | Medipol University | 33 | 2025-07-19 | 2026-03-17 |
| The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients Intervention 1, Intervention 2, Control - Delirium | Phase 2 / Phase 3 | Recruiting | Sultan Qaboos University | 240 | 2024-09-30 | 2025-01-14 |
| The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care Acute high altitude exposure, Acute high altitude exposure, with supplementary oxygen, Subacute high altitude exposure, after having spent a night at high altitude - High Altitude, Hypobaric Hypoxia | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 20 | 2024-08-02 | 2026-04-29 |
| Using the Visualization for Lifestyle Change in Patients At Risk of Cardiovascular Diseases CGM, Visualization - Cardiovascular Diseases, Coronary Artery Disease | Not applicable | Completed | University Maribor | 120 | 2024-05-06 | 2025-01-24 |
| Optimizing the Patient Experience Through Provider Coaching or Communication Intervention Intervention 1 - Patient Satisfaction, Communication | Not applicable | Active not recruiting | Mayo Clinic | 45 | 2024-03-08 | 2026-10-14 |
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Breast Neoplasms (2) · Colorectal Neoplasms (2) · Dry Eye Syndromes (2) · Obesity (2) · Acquired Immunodeficiency Syndrome (1) · Agnosia (1) · Altitude Sickness (1) · Autism Spectrum Disorder (1) · Bile Duct Neoplasms (1) · COVID-19 (1) · Cardiovascular Diseases (1) · Carotid Stenosis (1) · Cholangiocarcinoma (1) · Chronic Pain (1) · Communication (1)
Hospital Universitari Vall d'Hebron Research Institute (2) · Lahore University of Biological and Applied Sciences (2) · Medical University of Vienna (2) · Alessandro Pasqualotto (1) · Atma Jaya Catholic University of Indonesia (1) · Betül Taş Özyurtseven (1) · Biolux Research Holdings, Inc. (1) · British Columbia Cancer Agency (1) · Cairo University (1) · Copenhagen Academy for Medical Education and Simulation (1) · Derya Kaya Senol (1) · Devicare S.L. (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Future University in Egypt (1) · Gødstrup Hospital (1)
United States (6) · Spain (5) · Turkey (Türkiye) (4) · Austria (2) · Brazil (2) · Australia (1) · Canada (1) · Denmark (1) · Egypt (1) · Germany (1) · Guinea-Bissau (1) · Indonesia (1) · Oman (1) · Pakistan (1) · Poland (1)
Ahmed Raslan, MD (1) · Alpesh Amin, MD (1) · Annette E Maxwell, Dr.P.H. (1) · Ayesha Naeem Khan, DPT (1) · Carmina Castellano-Tejedor, PhD (1) · Christine Dawczynski, PhD (1) · Cleber R. P. Kruel, Professor (1) · Conchitta D'Ambrosio, MSc, PhD (1) · Daiane Dalla Lana, PhD (1) · David R Walega, MD (1)
PMID 18708385, PMID 20864724, PMID 21111754, PMID 24278919, PMID 28566263, PMID 30155282, PMID 30732583, PMID 31345971, PMID 33608403, PMID 33632282, PMID 34893053, PMID 36763614, PMID 36819683, PMID 37608473, PMID 38375882, PMID 39083331, PMID 39208325, PMID 39742454, PMID 40000080, PMID 41569629, PMID 41592826