10 completed, 3 unknown, 2 terminated, 2 withdrawn. 17 Phase 2, 4 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 10, Unknown 3, Terminated 2, Withdrawn 2 |
| Phase 1 | 4 | Withdrawn 2, Completed 1, Unknown 1 |
| Phase 3 | 2 | Terminated 1, Unknown 1 |
Follow Interferons: new trials by email Literature Review of Interferons trials Research Report on Interferons
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis Interferon, Sodium Hyaluronate, Sodium Chloride Injection - Interstitial Cystitis | Phase 2 / Phase 3 | Unknown | West China Hospital | 129 | 2023-10-15 | 2023-09-15 |
| Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer CG0070 Adenovirus Vector, Control Arm: Quadruple Choice - Transitional Cell Carcinoma, Bladder Cancer | Phase 2 / Phase 3 | Terminated | CG Oncology, Inc. | 22 | 2014-03-01 | 2021-04-14 |
| A Phase II Study of Imatinib Versus Interferon as Adjuvant Therapy in KIT-mutated Melanoma imatinib, Interferon - Melanoma | Phase 2 | Unknown | Peking University Cancer Hospital & Institute | 40 | 2012-08-01 | 2013-02-04 |
| 5-Fluorouracil Followed by Interferon-alfa-2b in Previously-treated Metastatic Gastrointestinal, Kidney, or Lung Cancer 5-Fluorouracil and Interferon - Gastrointestinal Cancer Metastatic, Renal Cell Cancer Metastatic | Phase 2 | Completed | Western Regional Medical Center | 18 | 2012-07-01 | 2018-03-21 |
| IPI-Biotherapy for Patients Previously Treated With Cytotoxic Drugs With Metastatic Melanoma Ipilimumab, Interferon, Interleukin-2 (Aldesleukin) - Melanoma | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2011-10-01 | 2012-01-26 | |
| Safety Study of Recombinant Interferon Variant(PEG-IFN-SA) to Treat HCV Disease interferon - Hepatitis C Virus | Phase 1 / Phase 2 | Completed | The First Hospital of Jilin University | 80 | 2011-06-01 | 2016-01-26 |
| Reactogenicity, Immunogenicity of Trivalent Influenza Vaccine With Recombinant Interferon Alpha Among Chronic Lymphocytic Leukemia Influenza Vaccine Trivalent Inactivated (TIV), Pegylated interferon (PEGrIFN-α, Pegasys), Interferon (IFNα, Roferon-A) - Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2011-04-01 | 2012-08-03 | |
| Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis conventional therapy plus MenSC transplantation, Conventional therapy plus placebo treatment - Liver Cirrhosis, Fibrosis | Phase 1 / Phase 2 | Unknown | S-Evans Biosciences Co., Ltd. | 50 | 2010-10-01 | 2012-06-07 |
| Interferon-alpha Lozenges for Prevention of Relapse in Hepatitis C interferon-alpha lozenges, placebo lozenges - Hepatitis C, Chronic | Phase 2 | Completed | Ainos, Inc. (f/k/a Amarillo Biosciences Inc. | 169 | 2009-06-01 | 2024-02-21 |
| A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following Unsuccessful Treatment With Sunitinib in Patients With Advanced Renal Cell Cancer. Sorafenib (Nexavar, BAY43-9006), Sorafenib (Nexavar, BAY43-9006) + Interferon - Carcinoma, Renal Cell | Phase 2 | Terminated | Bayer | 16 | 2008-04-01 | 2014-12-11 |
| Advanced Cervical Cancer Trial in India Interferon, Retinoic Acid and radiation, Cisplatin and radiation - Cervical Cancer | Phase 2 | Completed | University of Louisville | 209 | 2007-10-01 | 2017-12-29 |
| Rituximab and CVP Plus Interferon for Follicular Non Hodgkins Lymphoma (NHL) R+CVP+IFN - Non-Hodgkin's Lymphoma | Phase 2 | Completed | Fundación Leucemia y Linfoma, Spain | 50 | 2006-02-01 | 2016-04-04 |
| BAY43-9006 (Sorafenib) Versus Interferon Alpha-2a in Patients With Unresectable and/or Metastatic Renal Cell Carcinoma Sorafenib (Nexavar, BAY43-9006), Interferon - Carcinoma, Renal Cell | Phase 2 | Completed | Bayer | 189 | 2005-06-01 | 2014-10-31 |
| Imatinib Mesylate With Vincristine and Dexamethasone in Acute Lymphoblastic Leukemias With BCR-ABL Positive Imatinib mesylate, Interferon, Vincristine - Leukemia, Lymphocytic, Acute, Philadelphia Chromosome | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 55 | 2004-12-01 | 2011-10-05 |
| Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma Thalidomide, alpha interferon, Thalidomide, interferon, Octreotide - Liver, Cancer | Phase 2 | Completed | University of New Mexico | 12 | 2000-09-01 | 2010-01-07 |
| Treatment and Natural History Study of Lymphomatoid Granulomatosis Interferon, Rituxan and EPOCH, Tumor biopsy - Lymphomatoid Granulomatosis, Granulomatosis, Lymphomatoid | Phase 2 | Completed | National Cancer Institute (NCI) | 94 | 1995-05-05 | 2025-06-19 |
| Interferon and Octreotide to Treat Zollinger-Ellison Syndrome and Advanced Non-B Islet Cell Cancer Interferon - Islet Cell Adenoma, Zollinger Ellison Syndrome | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 50 | 1988-10-25 | 2017-07-02 |
Neoplasms (3) · Carcinoma, Renal Cell (2) · Lymphoma, Non-Hodgkin (2) · Melanoma (2) · Adenoma, Islet Cell (1) · Adenoviridae Infections (1) · Blast Crisis (1) · Carcinoma in Situ (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Transitional Cell (1) · Cystitis, Interstitial (1) · Digestive System Diseases (1) · Epstein-Barr Virus Infections (1) · Fibrosis (1) · Hepatitis C (1)
Bayer (2) · M.D. Anderson Cancer Center (2) · Ainos, Inc. (f/k/a Amarillo Biosciences Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · CG Oncology, Inc. (1) · Fundación Leucemia y Linfoma, Spain (1) · National Cancer Institute (NCI) (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Peking University Cancer Hospital & Institute (1) · S-Evans Biosciences Co., Ltd. (1) · The First Hospital of Jilin University (1) · University of Louisville (1) · University of New Mexico (1) · West China Hospital (1) · Western Regional Medical Center (1)
United States (6) · China (3) · France (3) · Poland (2) · Spain (2) · United Kingdom (2) · Austria (1) · Germany (1) · India (1) · Ireland (1) · Italy (1) · Russia (1) · Taiwan (1) · Ukraine (1)
Agop Y. Bedikian, MD,BS (1) · Alex W Yeung, MBBS (1) · Amar Safdar, MD (1) · Charlie Xiang, Professor (1) · Christopher J Melani, M.D. (1) · Ian Rabinowitz, MD (1) · Jun Guo, M.D. (1) · Partha S Basu, MD (1) · Reyes Arranz-Saez, MD (1) · Walter Quan, MD (1) · Wei-min Li (1)
PMID 19171708, PMID 24237300, PMID 26700705, PMID 37011643, PMID 37146227, PMID 38587846
2005 (1)