6 completed, 1 not yet recruiting, 1 unknown. 3 Phase 3, 2 Not applicable, 2 Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow High-Frequency Ventilation: new trials by email Literature Review of High-Frequency Ventilation trials Research Report on High-Frequency Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Hemodynamic Impact of High-frequency Oscillatory Ventilation and Periodic Sighs in Preterm Infants Superimposed sigh breaths, High frequency ventilation - Preterm, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Alexandria University | 100 | 2026-11-15 | 2026-10-27 |
| Nondependent Lung Ventilation and Fluid Responsiveness High Frequency Positive Pressure Ventilation, Continuous Positive Airway Pressure - Lung Disease, Undergoing Thoracosocpic Surgery | Phase 3 | Unknown | Imam Abdulrahman Bin Faisal University | 62 | 2019-01-01 | 2018-05-24 |
| Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO High Frequency Oscillation - Acute Respiratory Distress Syndrome, Acute Cor Pulmonale | Phase 1 | Completed | University of Athens | 17 | 2014-01-01 | 2017-08-17 |
| High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG) Apnea, High frequency ventilation - Coronary Artery Bypass Graft | Phase 4 | Completed | Montreal Heart Institute | 80 | 2009-11-01 | 2016-03-16 |
| Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure High-frequency Oscillation and Tracheal Gas Insufflation - Respiratory Distress Syndrome | Phase 2 / Phase 3 | Completed | University of Athens | 124 | 2008-03-01 | 2016-11-21 |
| The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study High-frequency oscillation, Conventional lung-open mechanical ventilation - Acute Respiratory Distress Syndrome | Not applicable | Completed | Canadian Critical Care Trials Group | 94 | 2007-06-01 | 2009-01-30 |
| Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome High Frequency Oscillation and Tracheal Gas Insufflation - Respiratory Distress Syndrome, Adult | Phase 1 / Phase 2 | Completed | University of Athens | 54 | 2006-07-01 | 2014-06-24 |
| High Frequency Ventilation in Premature Infants (HIFI) high-frequency ventilation - Bronchopulmonary Dysplasia, Lung Diseases | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1984-08-01 | 2016-04-14 |
Respiratory Distress Syndrome (5) · Lung Diseases (2) · Respiratory Aspiration (2) · Bronchopulmonary Dysplasia (1) · Premature Birth (1) · Pulmonary Heart Disease (1) · Ventilator-Induced Lung Injury (1)
University of Athens (3) · Alexandria University (1) · Canadian Critical Care Trials Group (1) · Imam Abdulrahman Bin Faisal University (1) · Montreal Heart Institute (1) · National Heart, Lung, and Blood Institute (NHLBI) (1)
Greece (3) · Canada (2) · Saudi Arabia (2)
Spyros D Mentzelopoulos, MD, PhD (2) · Spyros G Zakynthinos, MD, PhD (2) · Abdulmohsen A Al Ghamdi, MD (1) · Alain Deschamps, MD FRCPC (1) · Charis Roussos, MD, PhD (1) · Charis Roussos, Professor (1) · Kenneth Poole (1) · Maureen O Meade, MD, MSc (1) · Mohamed R El Tahan, MD (1) · Niall D Ferguson, MD, MSc (1) · Sotiris M Malachias, Consultant (1) · Sotiris Malachias, MD (1) · Spyros D Mentzelopoulos, Lecturer (1) · Spyros G Zakynthinos, As Professor (1)