9 completed, 6 unknown, 1 terminated, 1 withdrawn. 11 Phase 2, 5 Phase 1, 1 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 5, Unknown 4, Terminated 1, Withdrawn 1 |
| Phase 1 | 5 | Completed 3, Unknown 2 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow genexol-PM: new trials by email Literature Review of genexol-PM trials Research Report on genexol-PM
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6 Paclitaxel, mFOLFOX6 regimen - Gastric Cancer Stage IV, Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Completed | Seoul National University Bundang Hospital | 35 | 2018-12-24 | 2023-12-05 |
| Paclitaxel-Avelumab for Angiosarcoma Avelumab, Paclitaxel - Angiosarcoma Metastatic | Phase 2 | Unknown | Sung Yong Oh | 32 | 2018-06-01 | 2018-07-11 |
| A Phase II Study of Weekly Genexol-PM in Patients With Hepatocelluar Carcinoma After Failure of Sorafenib Genexol-PM - Carcinoma, Hepatocellular | Phase 2 | Terminated | Gachon University Gil Medical Center | 5 | 2016-10-01 | 2021-02-04 |
| Study of Weekly Genexol®-PM Plus Gemcitabine in Subjects With Recurrent and Metastatic Adenocarcinoma of the Pancreas Genexol-PM, Gemcitabine - Recurrent Adenocarcinoma of the Pancreas, Metastatic Adenocarcinoma of the Pancreas | Phase 2 | Unknown | Samyang Biopharmaceuticals Corporation | 47 | 2016-04-01 | 2018-04-18 |
| Study to Evaluate the Efficacy and Safety of Genexol-PM Once a Week for Gynecologic Cancer Genexol-PM - Gynecologic Cancer | Phase 1 | Unknown | Samyang Biopharmaceuticals Corporation | 18 | 2016-04-01 | 2017-05-01 |
| Eribulin Plus Gemcitabine (EG) vs Paclitaxel Plus Gemcitabine (PG) in HER2-Negative Metastatic Breast Cancer Paclitaxel, Eribulin, Gemcitabine - Metastatic Breast Cancer | Phase 2 | Completed | Asan Medical Center | 118 | 2014-12-19 | 2020-07-14 |
| Bioequivalence Study of IG-001 Versus Nab-paclitaxel in Metastatic or Locally Recurrent Breast Cancer Nab-paclitaxel, IG-001 - Metastatic Breast Cancer, Locally Recurrent Breast Cancer | Not applicable | Completed | Sorrento Therapeutics, Inc. | 111 | 2014-03-01 | 2016-03-25 |
| A Phase II Trial of Doxorubicin and Genexol-PM in Patients With Advanced Breast Cancer Doxorubicin/Genexol-PM - Metastatic Breast Cancer | Phase 2 | Unknown | Gachon University Gil Medical Center | 48 | 2011-01-01 | 2016-02-10 |
| A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer Paclitaxel loaded Polymeric micelle - Recurrent Breast Cancer | Phase 4 | Unknown | Korean Breast Cancer Study Group | 90 | 2009-05-01 | 2009-06-16 |
| Evaluate the Efficacy and Safety of Genexol®-PM Compared to Genexol® in Recurrent or Metastatic Breast Cancer Genexol-PM®, Genexol® - Breast Cancer | Phase 3 | Completed | Samyang Biopharmaceuticals Corporation | 213 | 2008-12-01 | 2017-05-01 |
| Trial to Determine the Maximum Tolerated Dose of Genexol-PM Plus Gemcitabine and Evaluate Efficacy and Safety of Genexol-PM Regimens in Subjects With Advanced Pancreatic Cancer Genexol-PM - Pancreatic Cancer | Phase 1 | Completed | Samyang Biopharmaceuticals Corporation | 18 | 2008-09-01 | 2017-05-05 |
| A Trial of Paclitaxel (Genexol®) and Cisplatin Versus Paclitaxel Loaded Polymeric Micelle (Genexol-PM®) and Cisplatin in Advanced Non Small Cell Lung Cancer Paclitaxel (Genexol®), Paclitaxel loaded polymeric micelle (Genexol-PM®) - Non Small Cell Lung Cancer | Phase 2 | Completed | Samyang Biopharmaceuticals Corporation | 276 | 2008-06-01 | 2017-05-09 |
| Paclitaxel-Loaded Polymeric Micelle and Carboplatin as First-Line Therapy in Treating Patients With Advanced Ovarian Cancer carboplatin, paclitaxel-loaded polymeric micelle - Ovarian Cancer | Phase 1 / Phase 2 | Unknown | Asan Medical Center | 74 | 2008-05-01 | 2013-08-02 |
| Determine MTD, Evaluate Efficacy and Safety of Genexol®-PM Plus Carboplatin With Advanced Ovarian Cancer Genexol-PM 220mg/㎡, Carboplatin 5AUC, Genexol-PM 260mg/㎡, Carboplatin 5AUC, Genexol-PM 300mg/㎡, Carboplatin 5AUC - Ovarian Cancer | Phase 1 | Completed | Samyang Biopharmaceuticals Corporation | 18 | 2008-05-01 | 2012-06-12 |
| Study of Genexol-PM in Patients With Advanced Urothelial Cancer Previously Treated With Gemcitabine and Platinum Genexol PM - Bladder Cancer, Ureter Cancer | Phase 2 | Completed | Asan Medical Center | 37 | 2007-12-01 | 2011-12-07 |
| Genexol-PM Versus Paclitaxel in Anthracycline-pretreated Metastatic Breast Cancer Patients Genexol-PM, Paclitaxel - Breast Cancer | Phase 2 | Withdrawn | National Cancer Center, Korea | 2007-07-01 | 2012-01-04 | |
| Paclitaxel in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer paclitaxel-loaded polymeric micelle - Pancreatic Cancer | Phase 2 | Completed | Theradex | 43 | 2005-05-01 | 2011-12-14 |
Breast Neoplasms (6) · Ovarian Neoplasms (2) · Pancreatic Neoplasms (2) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Transitional Cell (1) · Digestive System Neoplasms (1) · Hemangiosarcoma (1) · Liver Diseases (1) · Liver Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms by Site (1) · Peritoneal Neoplasms (1) · Recurrence (1)
Samyang Biopharmaceuticals Corporation (6) · Asan Medical Center (3) · Gachon University Gil Medical Center (2) · Korean Breast Cancer Study Group (1) · National Cancer Center, Korea (1) · Seoul National University Bundang Hospital (1) · Sorrento Therapeutics, Inc. (1) · Sung Yong Oh (1) · Theradex (1)
South Korea (12) · United States (2) · Georgia (1) · Moldova (1) · Romania (1) · Serbia (1) · Singapore (1) · Ukraine (1)
Yong Man Kim, MD, PhD (2) · Byoung Gie Kim, MD, PhD (1) · Byung-Joo Song, MD.PhD. (1) · Dong Bok Shin, Professor (1) · Hyun Woo Lee, M.D. (1) · Hyung-Ho Kim, M.D., PhD. (1) · Jae-Lyun Lee, M.D., Ph.D. (1) · John S. MacDonald, MD (1) · Jungsil Ro, Ph,D (1) · Kyung Hae Jung, Dr (1) · Soon Beom Kang, MD, PhD (1) · Sun Young Kim, Ph.D. (1) · Yong Man Kim (1) · Young Tae Kim, MD, PhD (1)