6 completed, 3 recruiting, 1 terminated, 1 unknown. 11 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 6, Recruiting 3, Terminated 1, Unknown 1 |
Follow Fosfomycin: new trials by email Literature Review of Fosfomycin trials Research Report on Fosfomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Combination Therapy With Ceftazidime and Fosfomycin Will be Compared to Ceftazidime Alone in Hospitalized Adult Patients With Suspected Severe Gram-negative Bacterial Infections Ceftazidime± avibactam with fosfomycin, Ceftazidime± avibactam with placebo - Gram Negative Infections, Sepsis and Septic Shock | Phase 3 | Recruiting | Angela HUTTNER | 100 | 2025-08-25 | 2025-09-26 |
| Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections Fosfomycin, Standard of care antibiotics - Urinary Tract Infections | Phase 3 | Recruiting | University of Sydney | 300 | 2023-08-02 | 2024-06-06 |
| Prevention of Iron Deficiency Anemia Post-delivery Ferric carboxymaltose (FCM) and folic acid tablets, Oral iron tablets and folic acid tablets - Postpartum Anemia | Phase 3 | Completed | NICHD Global Network for Women's and Children's Health | 4857 | 2023-05-30 | 2026-07-01 |
| Clinical Trial of Pivmecillinam Hydrochloride Tablets in the Treatment of Uncomplicated Urinary Tract Infection Pivmecillinam hydrochloride tablets, Fosfomycin Tromethamine Granules - Uncomplicated Urinary Tract Infection | Phase 3 | Completed | Benova (Tianjin) Innovative medicine Research Co., Ltd. | 299 | 2022-09-29 | 2024-04-17 |
| Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC) Ferinject, Conservative management - Advanced Gastric Carcinoma | Phase 3 | Recruiting | Asan Medical Center | 330 | 2022-04-29 | 2026-04-03 |
| A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia (FOVOCIP) Fosfomycin, ciprofloxacin - Haematopoietic Stem Cell Transplantation, Acute Leukemia | Phase 3 | Completed | Fundación para la Investigación Biosanitaria del Principado de Asturias | 177 | 2022-03-14 | 2026-06-01 |
| EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care Fosfomycin, Nitrofurantoin - Urinary Tract Infections | Phase 3 | Terminated | MJM Bonten | 13 | 2021-09-06 | 2022-03-15 |
| New AntiBiotic Treatment Options for Uncomplicated Anogenital GOnorrhoea Ertapenem 1000 MG, Fosfomycin Oral Suspension, Gentamicin Sulfate, Injectable - Gonorrhea | Phase 3 | Completed | Public Health Service of Amsterdam | 346 | 2017-09-18 | 2021-08-06 |
| Efficacy of CLR Compared to Fosfomycin Trometamol in Acute Lower uUTIs Canephron® N, Fosfomycin trometamol, Canephron® N-placebo - Urinary Tract Infection | Phase 3 | Completed | Bionorica SE | 659 | 2015-12-01 | 2017-07-28 |
| Colistin Versus Colistin Plus Fosfomycin for Infections Caused by MDR Acinetobacter Baumannii colistin, colistin plus fosfomycin - Drug Safety | Phase 3 | Unknown | Mahidol University | 92 | 2010-06-01 | 2011-12-29 |
| Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) FCM (Ferric carboxymaltose) high ferritin target, FCM (Ferric carboxymaltose) low ferritin target, Oral Iron (Ferrous sulphate) - Iron Deficiency Anaemia, Chronic Kidney Disease | Phase 3 | Completed | Vifor Pharma | 626 | 2009-12-01 | 2014-05-20 |
Urinary Tract Infections (3) · Anemia (1) · Anemia, Iron-Deficiency (1) · Gonorrhea (1) · Renal Insufficiency, Chronic (1) · Sepsis (1) · Shock, Septic (1)
Angela HUTTNER (1) · Asan Medical Center (1) · Benova (Tianjin) Innovative medicine Research Co., Ltd. (1) · Bionorica SE (1) · Fundación para la Investigación Biosanitaria del Principado de Asturias (1) · MJM Bonten (1) · Mahidol University (1) · NICHD Global Network for Women's and Children's Health (1) · Public Health Service of Amsterdam (1) · University of Sydney (1) · Vifor Pharma (1)
Netherlands (3) · Australia (2) · Germany (2) · Spain (2) · Austria (1) · Bangladesh (1) · Belgium (1) · China (1) · Czechia (1) · Democratic Republic of the Congo (1) · Denmark (1) · France (1) · Greece (1) · Guatemala (1) · India (1)
Florian Wagenlehner, Prof. (1) · Henry JC de Vries, PhD, MD (1) · Iain Macdougall (1) · Marc Bonten, Prof. (1) · Phoebe Williams (1) · Richard J Derman, MD, MPH (1) · Teresa Bernal, MD OHD (1) · Visanu Thamlikitkul, MD (1) · Xiangdong Yang, PhD (1)
PMID 24891437, PMID 24982065, PMID 28095881, PMID 28339831, PMID 30231252, PMID 35065063, PMID 35820778, PMID 41545057