9 completed, 3 terminated, 2 unknown, 1 withdrawn. 4 Phase 4, 3 Phase 1, 3 Phase 3, 2 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Not applicable | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow Flucloxacillin: new trials by email Literature Review of Flucloxacillin trials Research Report on Flucloxacillin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Flucloxacillin as an Inducer of CYP-enzymes Flucloxacillin - Healthy Volunteers, Drug Drug Interaction | Phase 1 | Completed | University of Southern Denmark | 14 | 2021-03-25 | 2022-01-11 |
| Penicillin Against Flucloxacillin Treatment Evaluation Benzylpenicillin, Flucloxacillin - Staphylococcus Aureus | Phase 4 | Withdrawn | The University of Queensland | 2019-07-01 | 2022-11-16 | |
| Pharmacokinetics of Flucloxacillin Given by Continuous or Intermittent Infusion to ICU Patients Flucloxacillin - Bacterial Infections | Completed | Radboud University Medical Center | 30 | 2017-06-01 | 2018-10-23 | |
| Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA Dalbavancin, Vancomycin, Oxacillin - Methicillin-Resistant Staphylococcus Aureus, Bacterial Infections | Phase 3 | Completed | AbbVie | 199 | 2017-03-30 | 2024-09-19 |
| Penicillin for the Emergency Department Outpatient Treatment of CELLulitis Flucloxacillin, Phenoxymethylpenicillin, Placebo (for phenoxymethylpenicillin) - Cellulitis, Wound Infection | Phase 4 | Unknown | Royal College of Surgeons, Ireland | 414 | 2016-12-01 | 2016-10-04 |
| Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients (TAPAS) amoxicillin-clavulanic acid - Surgery | Unknown | Universitaire Ziekenhuizen KU Leuven | 120 | 2016-11-30 | 2017-04-20 | |
| Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection Beta-Lactam - Methicillin-Resistant Staphylococcus Aureus | Phase 3 | Terminated | Menzies School of Health Research | 358 | 2015-08-26 | 2018-12-19 |
| Comparing the Intravenous Treatment of Skin Infections in Children, Home Versus Hospital Home, Ward, ceftriaxone - Cellulitis | Not applicable | Completed | Murdoch Childrens Research Institute | 190 | 2015-01-01 | 2022-11-08 |
| Duration of ANtibiotic Therapy for CEllulitis Flucloxacillin, Placebo (for flucloxacillin) - Cellulitis, Erysipelas | Phase 4 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 151 | 2014-08-26 | 2017-10-10 |
| Staphylococcus Aureus Bacteremia Antibiotic Treatment Options Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid - Staphylococcus Aureus Infection | Phase 3 | Completed | Heinrich-Heine University, Duesseldorf | 215 | 2013-12-01 | 2020-05-27 |
| Adjunctive Clindamycin for Cellulitis: C4C Trial. Flucloxacillin, Clindamycin, Placebo oral capsule - Cellulitis | Phase 4 | Completed | University Hospitals Bristol and Weston NHS Foundation Trust | 410 | 2013-10-01 | 2022-08-17 |
| Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci daptomycin, vancomycin, teicoplanin - Osteomyelitis | Phase 2 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 75 | 2007-06-26 | 2018-01-31 |
| The Effect of Antimicrobial Therapy on the Serum Level of P-cresol in Peritoneal Dialysis Patients Flucloxacillin - Chronic Kidney Disease | Phase 1 | Terminated | Universitaire Ziekenhuizen KU Leuven | 9 | 2006-03-01 | 2020-04-27 |
| Bioavailability Of Flucloxacillin Capsules (250 mg and 500 mg) flucloxacillin 250 mg, flucloxacillin 500 mg - Infections, Bacterial | Phase 1 | Completed | GlaxoSmithKline | 24 | 2005-01-06 | 2017-09-29 |
| Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding Acupuncture treatment, Administration of oxytocin nasal spray, Improved breast milk removal - Mastitis | Not applicable | Completed | Karlstad University | 210 | 2002-01-01 | 2006-12-04 |
Cellulitis (4) · Bacterial Infections (3) · Staphylococcal Infections (3) · Abscess (1) · Breast Feeding (1) · Erysipelas (1) · Mastitis (1) · Osteomyelitis (1) · Renal Insufficiency, Chronic (1) · Sepsis (1) · Staphylococcal Skin Infections (1) · Wound Infection (1)
Universitaire Ziekenhuizen KU Leuven (2) · AbbVie (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · GlaxoSmithKline (1) · Heinrich-Heine University, Duesseldorf (1) · Karlstad University (1) · Menzies School of Health Research (1) · Murdoch Childrens Research Institute (1) · Radboud University Medical Center (1) · Royal College of Surgeons, Ireland (1) · The University of Queensland (1) · University Hospitals Bristol and Weston NHS Foundation Trust (1) · University of Southern Denmark (1)
Australia (3) · Netherlands (3) · United Kingdom (3) · Belgium (2) · Germany (2) · Russia (2) · Spain (2) · United States (2) · Argentina (1) · Belarus (1) · Brazil (1) · Bulgaria (1) · Chile (1) · Colombia (1) · Denmark (1)
Abel Wakai, MD FRCEM (1) · Achim J Kaasch, MD (1) · Adrian Moughty (1) · Alistair Wheeler, MD (1) · Bodil Wilde Larsson, PhD (1) · Chris Luke (1) · Conor Deasy (1) · David Paterson (1) · Jan M. Prins, MD, PhD (1) · Joseph McKeever (1) · Joshua Davis, MBBS, FRACP (1) · Laila F Ibrahim, MBBChBAO (1)
PMID 22908174, PMID 24885384, PMID 26452342, PMID 26754176, PMID 27029920, PMID 28314743, PMID 28836993, PMID 30321312, PMID 30853250, PMID 31420292, PMID 32044943, PMID 32051007, PMID 38244557
2014 (1)