12 completed, 3 unknown, 1 not yet recruiting, 1 suspended. 12 Not applicable, 3 Phase 4, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 8, Unknown 2, Suspended 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
Follow Filtered Air: new trials by email Literature Review of Filtered Air trials Research Report on Filtered Air
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Air Pollution and Inhaled Corticosteroids in COPD LABA+LAMA, LABA+LAMA+ICS, Filtered Air - COPD | Phase 4 | Not yet recruiting | University of British Columbia | 48 | 2025-04-01 | 2025-03-27 |
| Investigating Changes in Responses to Controlled Effective Doses of Ozone at Different Exercise Intensities Ozone, Heavy Intensity, Moderate Intensity - Ozone, Exercise Intensity | Not applicable | Withdrawn | Michael Koehle | 2024-09-01 | 2025-03-30 | |
| Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB) Salbutamol, Placebo medication, Ozone - Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution | Phase 4 | Completed | University of British Columbia | 18 | 2021-11-01 | 2025-03-14 |
| Cardiovascular Effects of Exposure to Wood Smoke in Healthy Human Adults Filtered Air, Wood Smoke - Healthy | Not applicable | Suspended | University of North Carolina, Chapel Hill | 80 | 2021-05-25 | 2025-06-12 |
| ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability Ozone, Filtered Air - Environmental and Genetic Factors on Lung Function | Early Phase 1 | Completed | Robert Tighe, MD | 14 | 2019-08-16 | 2026-06-15 |
| Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis Ozone, Filtered Air - Healthy | Phase 1 | Completed | Robert Tighe, MD | 35 | 2019-03-19 | 2026-06-15 |
| Effects on the Olfactory Epithelium and the Olfactory Nerve From Exposure to Diesel Exhaust Diesel Exhaust Particles, Filtered air - Alzheimer Disease (AD), Dementia Alzheimer Type | Not applicable | Completed | Umeå University | 40 | 2019-02-01 | 2025-11-20 |
| Diesel Exhaust Induces Glucocorticoid Resistance Placebo, Budesonide, Filtered Air - Exposure to Pollution, Glucocorticoid Resistance | Phase 4 | Unknown | University of British Columbia | 30 | 2018-12-01 | 2024-07-24 |
| The Role of Eicosanoids in the Cardiovascular Actions of Inhaled Nanoparticles diesel exhaust particulate, carbon nanoparticles, small graphene oxide - Blood Biomarkers, Vasodilation | Not applicable | Completed | University of Edinburgh | 26 | 2018-10-03 | 2024-05-21 |
| Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects Ozone, Fish Oil, Olive Oil - Healthy, Dietary Supplement | Phase 1 | Completed | University of North Carolina, Chapel Hill | 44 | 2017-12-18 | 2021-01-15 |
| Human Biological Responses to Low Level Ozone Ozone, Filtered Air, Health and Exposure Tracker (HET) - Environmental Exposure, Nasal Inflammation | Not applicable | Completed | University of North Carolina, Chapel Hill | 15 | 2017-04-22 | 2021-05-14 |
| The Phthalate-Allergen Immune Response Study Phthalate, Filtered Air, Allergen - Allergies | Not applicable | Unknown | University of British Columbia | 20 | 2017-02-02 | 2019-08-02 |
| Longitudinal Acute Air Pollution Systemic Effects Diesel Exhaust, Filtered air - Healthy | Not applicable | Completed | Umeå University | 30 | 2015-11-01 | 2016-05-13 |
| Exercise in Air Pollution and Lung Health in Asthmatics Rest (Sitting on chair), Cycling exercise, Salbutamol inhalation - Exercise-induced Bronchoconstriction, Air Pollution | Not applicable | Completed | University of British Columbia | 20 | 2015-05-01 | 2021-09-30 |
| Effect of Commute Traffic on Vascular Function Filtered Air - Cardiovascular Diseases | Not applicable | Completed | University of Washington | 16 | 2015-01-01 | 2022-07-12 |
| Diesel Exhaust and Vascular Function Diesel Exhaust, Filtered Air, Terazosin - Cardiovascular Effects | Not applicable | Unknown | University of Washington | 24 | 2012-01-01 | 2015-08-03 |
| Diesel Exhaust and Mechanism of Asthma N-acetylcysteine, Diesel exhaust, Filtered air - Asthma | Not applicable | Completed | University of British Columbia | 26 | 2007-09-01 | 2017-09-29 |
| Physiological Changes in Adults With Metabolic Syndrome Exposed to Ultrafine Air Particles Ultrafine Air Pollution Particulate Matter, Filtered Air - Metabolic Syndrome | Not applicable | Completed | David Diaz-Sanchez | 48 | 2004-12-01 | 2013-11-07 |
Asthma (3) · Alzheimer Disease (1) · Aneurysm (1) · Cardiovascular Diseases (1) · Dyspnea (1) · Glucocorticoid Receptor Deficiency (1) · Hypersensitivity (1) · Metabolic Syndrome (1) · Motor Activity (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Aspiration (1) · Thrombosis (1)
University of British Columbia (6) · University of North Carolina, Chapel Hill (3) · Robert Tighe, MD (2) · Umeå University (2) · University of Washington (2) · David Diaz-Sanchez (1) · Michael Koehle (1) · University of Edinburgh (1)
United States (8) · Canada (6) · Sweden (2) · United Kingdom (1)
Christopher Carlsten, MD, MPH (2) · Christopher F Rider, PhD (2) · James Samet, PhD (2) · Robert Tighe, MD (2) · Candice B Smith, PhD (1) · Chris Carlsten, MD (1) · Christopher Carlsten, MD MPH (1) · David B Peden, MD (1) · Janice Leung, MD, FRCPC (1) · Jenny Bosson, MD, PhD (1) · Joel D Kaufman, MD, MPH (1) · Joel Kaufman, MD (1) · Michael Koehle, MD, PhD (1) · Michael S Koehle, MD, PhD (1) · Neeloffer Mookherjee, PhD (1)
PMID 32320637, PMID 36114491, PMID 38011704, PMID 38366225
K24ES013195 (1), P50ES015915 (1)