12 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 7 Not applicable, 4 Phase 4, 2 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 4 | Completed 4 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow esomeprazole 40 mg: new trials by email Literature Review of esomeprazole 40 mg trials Research Report on esomeprazole 40 mg
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metronidazole- Versus Tinidazole-Based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication Metronidazole, Tinidazole 500mg, tetracyline - Helicobacter Pylori Infection | Not applicable | Not yet recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 600 | 2026-07-27 | 2026-08-05 |
| Esomeprazole and Radiation Induced Esophagitis Esomeprazole 40 mg - Radiation Esophagitis, Locally Advanced Lung Carcinoma | Phase 2 | Recruiting | Rush University Medical Center | 48 | 2024-03-01 | 2026-08-14 |
| Study to Evaluate Effects of Food or Proton Pump Inhibitor on the Pharmacokinetics of Itraconazole in Healthy Volunteers Itraconazole 200 mg, Esomeprazole 40 mg - Achlorhydria | Phase 1 | Completed | Seoul National University Hospital | 13 | 2021-07-13 | 2021-09-29 |
| Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers Atovaquone / Proguanil 250/100 mg, Tegoprazan 50 mg, Esomeprazole 40 mg - Gastroesophageal Reflux Disease | Phase 1 | Completed | Seoul National University Hospital | 19 | 2020-11-25 | 2021-09-27 |
| Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori Infection 10d TL quadruple therapy, 10d AL quadruple therapy - Helicobacter Pylori Infection | Not applicable | Completed | Ping-I (William) Hsu, M.D. | 112 | 2018-07-11 | 2023-10-26 |
| Esomeprazole or Pantoprazole in Renal Transplantation Esomeprazole 40 mg, Pantoprazole 40mg - Kidney Transplant; Complications | Not applicable | Completed | Future University in Egypt | 47 | 2016-01-05 | 2019-01-24 |
| Levofloxacin Triple and Bismuth Quadruple Therapies for Rescue Treatment of H Pylori Infection esomeprazole+amox+levo, esomeprazole+bismuth+tetra+levo - Helicobacter Pylori Infection | Not applicable | Completed | Kaohsiung Veterans General Hospital. | 102 | 2015-02-01 | 2019-03-14 |
| Comparison of Two Rescue Therapies for Helicobacter Pylori Infection esomeprazole+amox+levo+tetra, esomeprazole+amox+levo - Helicobacter Pylori Infection | Not applicable | Completed | Kaohsiung Veterans General Hospital. | 51 | 2013-11-01 | 2019-03-14 |
| To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole esomeprazole 40 mg - Heartburn | Phase 4 | Completed | AstraZeneca | 101 | 2010-11-01 | 2012-10-31 |
| Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy Esomeprazole 40 mg - Erosive Esophagitis | Phase 4 | Completed | Chang Gung Memorial Hospital | 408 | 2010-06-01 | 2018-09-04 |
| Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance esomeprazole 40 mg - GERD | Not applicable | Completed | David A. Johnson, MD | 18 | 2008-07-01 | 2012-02-22 |
| vMII for Measurement of Oesophageal Bolus Transport and Reflux Heller's Myotomy, Nissen Fundoplication, domperidone or esomeprazole (Conservative management) - Achalasia, GORD | Not applicable | Terminated | Guy's and St Thomas' NHS Foundation Trust | 140 | 2007-11-01 | 2009-08-03 |
| A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI) Esomeprazole 40 mg, Physical Exam, Quality of Life Questionnaires - Gastroesophageal Reflux Disease | Phase 4 | Completed | AstraZeneca | 314 | 2007-11-01 | 2012-10-10 |
| Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit esomeprazole 40 mg, famotidine 20 mg - Ulcer | Phase 4 | Completed | Far Eastern Memorial Hospital | 60 | 2007-09-01 | 2013-10-16 |
| Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) Esomeprazole 40 mg, Esomeprazole 20 mg, Placebo - Gastric Ulcer, Duodenal Ulcer | Phase 3 | Completed | AstraZeneca | 2426 | 2007-02-01 | 2012-07-16 |
Gastroesophageal Reflux (3) · Heartburn (2) · Achlorhydria (1) · Deglutition Disorders (1) · Duodenal Ulcer (1) · Esophageal Achalasia (1) · Peptic Ulcer (1) · Stomach Ulcer (1) · Ulcer (1)
AstraZeneca (3) · Kaohsiung Veterans General Hospital. (2) · Seoul National University Hospital (2) · Chang Gung Memorial Hospital (1) · David A. Johnson, MD (1) · Far Eastern Memorial Hospital (1) · Future University in Egypt (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Ping-I (William) Hsu, M.D. (1) · Rush University Medical Center (1) · University of Medicine and Pharmacy at Ho Chi Minh City (1)
Taiwan (5) · South Korea (3) · United States (3) · Argentina (2) · Australia (1) · Bulgaria (1) · Canada (1) · Chile (1) · China (1) · Colombia (1) · Czechia (1) · Finland (1) · Germany (1) · Indonesia (1) · Mexico (1)
Ping-I Hsu, Bachelor (2) · SeungHwan Lee, MD, PhD (2) · Doaa MS ElBohy, M.Sc (1) · James Scheiman, MD (1) · Mark Fox, MD (1) · Masataka Date, MD, PhD (1) · Ping-I Hsu (1) · Seng-Kee Chuah, M.D (1) · Soumyajit M Roy, PhD (1) · Tore Lind, MD, PhD (1) · Tzong-Hsi Lee, M.D. (1)