20 completed. 20 Phase 2, 5 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 20 |
| Phase 3 | 5 | Completed 5 |
| Phase 1 | 2 | Completed 2 |
Follow Dutasteride: new trials by email Literature Review of Dutasteride trials Research Report on Dutasteride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial of Safety and Efficacy of Daily Application of Topical Dutasteride in Men With Androgenic Alopecia. Dutasteride, Placebo - Male Androgenetic Alopecia | Phase 2 | Completed | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 45 | 2022-09-29 | 2024-09-19 |
| EAT-DUTA AndroCoV Trial Dutasteride 0.5 mg, Azithromycin, Nitazoxanide - Covid19 | Phase 2 / Phase 3 | Completed | Corpometria Institute | 138 | 2020-06-30 | 2021-01-28 |
| Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy Dutasteride Capsules, Placebo Capsules - Alcohol Use Disorder | Phase 2 / Phase 3 | Completed | UConn Health | 180 | 2019-10-15 | 2025-05-09 |
| Role of Dutasteride in Treatment of Chronic Prostatitis Dutasteride 0.5 mg, Placebo - Dutasteride, Category IIIB Chronic Prostatitis | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2019-01-01 | 2021-02-16 |
| Enzalutamide & Dutasteride/Finasteride as 1st Line Treatment for Patients =/> 65 Years Old With Prostate Cancer. Enzalutamide and Dutasteride or finasteride - Prostate Cancer | Phase 2 | Completed | University of Rochester | 43 | 2014-09-01 | 2024-11-13 |
| Study of Enzalutamide (Formerly MDV3100) as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer Enzalutamide, Leuprolide, Dutasteride - Prostate Cancer | Phase 2 | Completed | Pfizer | 52 | 2012-03-31 | 2018-10-23 |
| Abiraterone Acetate Combined With Dutasteride for Metastatic Castrate Resistant Prostate Cancer Abiraterone acetate, Dutasteride, Prednisone - Prostate Cancer | Phase 2 | Completed | Mary-Ellen Taplin, MD | 40 | 2011-09-01 | 2018-03-15 |
| ITT4 Intratesticular Hormonal Milieu in Man (ITT4) Acyline, Testosterone gel, ketoconazole 400 - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 46 | 2011-01-01 | 2014-03-31 |
| Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for Brachytherapy administration of a LHRH agonist and Bicalutamide, administration of Bicalutamide, Dutasteride and Tamoxifen - Prostate Cancer, Erectile Dysfunction | Phase 2 | Completed | CHU de Quebec-Universite Laval | 60 | 2009-03-01 | 2023-06-02 |
| PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue Testosterone gel, Dutasteride, Depo-Medroxyprogesterone (DMPA) - Healthy | Phase 2 / Phase 3 | Completed | University of Washington | 32 | 2009-01-01 | 2013-11-15 |
| ARTS - AVODART After Radical Therapy For Prostate Cancer Study Avodart, placebo - Neoplasms, Prostate, Prostate Cancer After a Radical Treatment | Phase 2 | Completed | GlaxoSmithKline | 294 | 2007-11-01 | 2012-03-21 |
| Effect of Dutasteride on Androgen-Response Gene Expression in Patients With Advanced Prostate Cancer Dutasteride, Placebo - Prostate Cancer | Phase 2 | Completed | Endeavor Health | 20 | 2007-03-01 | 2023-08-22 |
| Comparing 0.5 mg Dutasteride vs Placebo Daily in Men Receiving Androgen Ablation Therapy for Prostate Cancer Dutasteride - Prostate Cancer | Phase 2 / Phase 3 | Completed | Canadian Urology Research Consortium | 100 | 2007-03-01 | 2016-10-14 |
| Oral Androgens in Man-4: (Short Title: Oral T-4) Testosterone Enanthate, Dutasteride, placebo sesame oil - Contraception | Phase 1 / Phase 2 | Completed | University of Washington | 20 | 2006-11-01 | 2008-09-22 |
| Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer goserelin with dutasteride, goserelin with bicalutamide and dutasteride, goserelin with bicalutamide and dutasteride and ketoconazole - Cancer, Prostate Neoplasms | Phase 2 | Completed | University of Washington | 35 | 2006-07-01 | 2018-08-09 |
| Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA) Dutasteride, Placebo - Kennedy's Disease, Spinal and Bulbar Muscular Atrophy | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 57 | 2006-03-01 | 2011-01-27 |
| Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone Oral Testosterone, Leuprolide (Lupron), Dutasteride - Contraception, Hypogonadism | Phase 2 | Completed | University of Washington | 18 | 2005-03-01 | 2008-09-19 |
| Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate Cancer Ketoconazole, Hydrocortisone and Dutasteride - Prostate Cancer | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 57 | 2005-02-01 | 2015-04-22 |
| Dutasteride in Treating Patients With Recurrent Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy dutasteride - Prostate Cancer | Phase 2 | Completed | Roswell Park Cancer Institute | 27 | 2004-12-01 | 2013-05-01 |
| Extension Study of GI198745 to Treat Benign Prostatic Hyperplasia GI198745 0.05mg, GI198745 0.5mg, GI198745 2.5mg - Benign Prostatic Hyperplasia, Prostatic Hyperplasia | Phase 2 | Completed | GlaxoSmithKline | 121 | 2003-08-01 | 2010-09-13 |
Prostatic Neoplasms (10) · Alcoholism (1) · Bulbo-Spinal Atrophy, X-Linked (1) · COVID-19 (1) · Erectile Dysfunction (1) · Hypogonadism (1) · Lower Urinary Tract Symptoms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Prostatic Hyperplasia (1)
University of Washington (5) · GlaxoSmithKline (2) · Ain Shams University (1) · Beth Israel Deaconess Medical Center (1) · CHU de Quebec-Universite Laval (1) · Canadian Urology Research Consortium (1) · Corpometria Institute (1) · Endeavor Health (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (1) · Mary-Ellen Taplin, MD (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Pfizer (1) · Roswell Park Cancer Institute (1) · UConn Health (1) · University of Rochester (1)
United States (13) · Canada (4) · Spain (2) · Brazil (1) · Egypt (1) · Estonia (1) · Finland (1) · France (1) · Germany (1) · Netherlands (1) · Russia (1) · Sweden (1) · United Kingdom (1)
Andre-Guy Martin, MD (1) · Andy Goren, MD (1) · Carlos G. Wambier, MD, Ph.D. (1) · Chunkit Fung, M.D. (1) · Daniel H Shevrin, MD (1) · Flavio A. Cadegiani, MD, MSc, Ph.D. (1) · James L. Mohler, MD (1) · John K Amory, MD, MPH (1) · Jonathan Covault, MD, PhD (1) · Kenneth Fischbeck, M.D. (1) · Larry S Goldeng (1) · Laurence Klotz, MD (1) · Mara Y Roth, MD (1) · Mary-Ellen Taplin, M.D. (1)
PMID 18046048, PMID 18077826, PMID 19091347, PMID 19846582, PMID 21216197, PMID 23176897, PMID 23348398, PMID 23533230, PMID 23851165, PMID 24323034, PMID 24876969, PMID 25091040, PMID 25320358, PMID 27683182, PMID 32134978, PMID 36570649
K23HD045386 (2), P50AA027055 (1), U54HD012629 (1), U54HD042454 (1)