4 unknown, 3 completed, 2 recruiting, 1 enrolling by invitation. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Unknown 4, Completed 3, Recruiting 2, Enrolling by invitation 1, Not yet recruiting 1 |
Follow doravirine: new trials by email Literature Review of doravirine trials Research Report on doravirine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sleep Outcomes and Multidimensional Sleep Assessment - a Randomized Trial of Dolutegravir- vs Doravirine-based Antiretroviral Therapy in People Living With HIV Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Doravirine 100mg, Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Dolutegravir 50mg - HIV (Human Immunodeficiency Virus), Sleep | Phase 4 | Not yet recruiting | University of Witwatersrand, South Africa | 40 | 2026-10-05 | 2026-10-06 |
| Efficacy and Safety of Doravirine in the Rapid Initiation Doravirine / lamivudine/ Tenofovir Disoproxil Oral Tablet - HIV-1-infection | Phase 4 | Recruiting | Fundación Huésped | 100 | 2026-09-16 | 2026-09-23 |
| Change in Body Weight and BMI in PWH with DOR/3TC/TDF Compared with INSTI Integrase inhibitor, Doravirine + tenofovir DF + lamivudine - HIV, HIV Associate Weight Loss | Phase 4 | Unknown | Instituto Mexicano del Seguro Social | 108 | 2024-08-14 | 2024-09-19 |
| B-free Multistage Trial DOR/DTG/3TC - HIV, Drug Resistance | Phase 4 | Enrolling by invitation | Insel Gruppe AG, University Hospital Bern | 210 | 2023-11-13 | 2024-12-04 |
| Doravirine Dose Optimisation in Pregnancy Doravirine, Dolutegravir - HIV | Phase 4 | Recruiting | University of Liverpool | 76 | 2023-10-10 | 2026-02-19 |
| Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers Doravirine 100Mg Tab, Biktarvy 50/200/25 Tab - Hiv | Phase 4 | Completed | Radboud University Medical Center | 20 | 2023-03-01 | 2026-04-16 |
| Switch Strategy From Etravirine (ETR) to Doravirine (DOR) in Virologically-Suppressed HIV-1 Infected Adults With ETR-Resistance Doravirine 100Mg Tab - HIV-1-infection | Phase 4 | Unknown | Fundacion Clinic per a la Recerca Biomédica | 12 | 2022-12-12 | 2023-09-21 |
| Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide Doravirine 100 Mg, Integrase strand transfer inhibitors, Tenofovir alafenamide/emtricitabine - HIV Infections | Phase 4 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 147 | 2021-07-27 | 2025-07-02 |
| Removal of Doravirine by Hemodialysis in HIV-Infected Patients With End-stage Renal Disease (ESRD) Doravirine - HIV-infected Participants With ESRD Undergoing Routine Hemodialysis | Phase 4 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 8 | 2021-03-20 | 2024-08-27 |
| Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil Dolutegravir/Lamivudine 50 MG-300 MG Oral Tablet [DOVATO], Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO] - Hiv, HIV Infections | Phase 4 | Unknown | Thomas Benfield | 126 | 2021-02-02 | 2021-05-27 |
| HIV Switch Trial in Experienced Patients With Multiple Class Resistance Including NNRTI Resistance Doravirine - HIV Infections | Phase 4 | Unknown | Clinique du Quartier Latin | 40 | 2020-06-23 | 2021-01-29 |
Acquired Immunodeficiency Syndrome (3) · HIV Infections (3) · Body Weight Changes (1) · Kidney Failure, Chronic (1) · Obesity (1) · Osteoporosis (1) · Renal Insufficiency (1) · Weight Gain (1) · Weight Loss (1)
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Clinique du Quartier Latin (1) · Fundacion Clinic per a la Recerca Biomédica (1) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (1) · Fundación Huésped (1) · Insel Gruppe AG, University Hospital Bern (1) · Instituto Mexicano del Seguro Social (1) · Radboud University Medical Center (1) · Thomas Benfield (1) · University of Liverpool (1) · University of Witwatersrand, South Africa (1)
Spain (2) · Argentina (1) · Canada (1) · Denmark (1) · Martinique (1) · Mexico (1) · Netherlands (1) · South Africa (1) · Switzerland (1) · United States (1)
Angela Colbers, PhD (1) · Francois WD Venter, PhD (1) · Gilles Wandeler, Prof (1) · John Koethe (1) · Saye Khoo (1) · Thomas Benfield, MD (1)
PMID 35425985, PMID 39578038, PMID 41847923
UM1AI068636 (1)